CRCGN016_MCF10A.WT.HP_24H:N18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinylidene chloride 11.7 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.67453
KDM5D lysine (K)-specific demethylase 5D 3.2515
SPAG4 sperm associated antigen 4 3.1642
BMP4 bone morphogenetic protein 4 2.9088
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.75385
IGFBP3 insulin-like growth factor binding protein 3 2.42662
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.2993
USP9Y ubiquitin specific peptidase 9, Y-linked 2.29778

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -4.65463
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.5608
HMG20B high mobility group 20B -3.51208
TSPAN4 tetraspanin 4 -3.27987
COG2 component of oligomeric golgi complex 2 -3.08887
MSN moesin -2.20297
ARID4B AT rich interactive domain 4B (RBP1-like) -2.16653
EXOSC4 exosome component 4 -2.08333
RXYLT1 ribitol xylosyltransferase 1 -2.02462