CRCGN016_MCF10A.WT.HP_24H:O03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

31 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 5.04091
EAPP E2F-associated phosphoprotein 4.79257
ADAM10 ADAM metallopeptidase domain 10 4.45536
TBX2 T-box 2 3.95942
HBA1 hemoglobin, alpha 1 3.80211
GATA2 GATA binding protein 2 3.69837
LYRM1 LYR motif containing 1 3.64781
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.2584
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.07166
BACE2 beta-site APP-cleaving enzyme 2 2.9309
AGR2 anterior gradient 2 2.92431
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.78592
ACAA1 acetyl-CoA acyltransferase 1 2.70886
RTN2 reticulon 2 2.39687
ARF6 ADP-ribosylation factor 6 2.34282
ZBTB35 zinc finger and BTB domain containing 35 2.16188
PDIA5 protein disulfide isomerase family A, member 5 2.03226
SPTSSA serine palmitoyltransferase, small subunit A 2.00788

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -2.90305
RXYLT1 ribitol xylosyltransferase 1 -2.88868
TIMP1 TIMP metallopeptidase inhibitor 1 -2.76813
RPS5 ribosomal protein S5 -2.63826
BASP1 brain abundant, membrane attached signal protein 1 -2.47694
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.46672
MTERF3 mitochondrial transcription termination factor 3 -2.1717
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.17103
ZNF750 zinc finger protein 750 -2.15014
PRCP prolylcarboxypeptidase (angiotensinase C) -2.0747
CREG1 cellular repressor of E1A-stimulated genes 1 -2.06941
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.05875
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.04385