| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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58 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | 5.46152 |
| CCP110 | centriolar coiled coil protein 110kDa | 3.91414 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.85145 |
| LAGE3 | L antigen family, member 3 | 3.83692 |
| AGR2 | anterior gradient 2 | 3.79735 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.60263 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 2.96435 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.93536 |
| NOSIP | nitric oxide synthase interacting protein | 2.82284 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.69013 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.51952 |
| CALML4 | calmodulin-like 4 | 2.51629 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.50584 |
| CHSY1 | chondroitin sulfate synthase 1 | 2.40261 |
| PARN | poly(A)-specific ribonuclease | 2.39518 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 2.37461 |
| OLFM1 | olfactomedin 1 | 2.29952 |
| LYSET | lysosomal enzyme trafficking factor | 2.27455 |
| SYT1 | synaptotagmin I | 2.26013 |
| TBPL1 | TBP-like 1 | 2.25001 |
| COMMD10 | COMM domain containing 10 | 2.23426 |
| BEX2 | brain expressed X-linked 2 | 2.22754 |
| IFI44L | interferon-induced protein 44-like | 2.21879 |
| MGST3 | microsomal glutathione S-transferase 3 | 2.20449 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 2.19149 |
| SLC25A40 | solute carrier family 25, member 40 | 2.16311 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.15323 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa | 2.08692 |
| STMN2 | stathmin 2 | 2.06564 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 2.04614 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TES | testin LIM domain protein | -5.51968 |
| HSPA8 | heat shock 70kDa protein 8 | -4.60309 |
| S100A8 | S100 calcium binding protein A8 | -4.02356 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -3.69979 |
| SORBS3 | sorbin and SH3 domain containing 3 | -3.34111 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.2879 |
| APEH | acylaminoacyl-peptide hydrolase | -3.14322 |
| IFRD2 | interferon-related developmental regulator 2 | -2.71211 |
| TMEM115 | transmembrane protein 115 | -2.58764 |
| TGM4 | transglutaminase 4 | -2.51825 |
| STK25 | serine/threonine kinase 25 | -2.47301 |
| CBR3 | carbonyl reductase 3 | -2.37075 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | -2.32576 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.31084 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -2.31004 |
| LMF2 | lipase maturation factor 2 | -2.26793 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | -2.21939 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -2.13857 |
| PSKH1 | protein serine kinase H1 | -2.12316 |
| RNF123 | ring finger protein 123 | -2.09681 |
| LYPD3 | LY6/PLAUR domain containing 3 | -2.0765 |
| MATK | megakaryocyte-associated tyrosine kinase | -2.06251 |
| DIPK1A | divergent protein kinase domain 1A | -2.06187 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | -2.05828 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) | -2.04882 |
| KRT14 | keratin 14, type I | -2.0205 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -2.01448 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -2.01235 |