| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG4 | sperm associated antigen 4 | 5.36472 |
| PDLIM1 | PDZ and LIM domain 1 | 5.34261 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 4.78124 |
| KDM5D | lysine (K)-specific demethylase 5D | 4.77056 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 4.49139 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.2343 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 3.58395 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.5056 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 3.046 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.80708 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.77815 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 2.66479 |
| ZFY | zinc finger protein, Y-linked | 2.60963 |
| NLGN4Y | neuroligin 4, Y-linked | 2.52266 |
| WIF1 | WNT inhibitory factor 1 | 2.46734 |
| MYL9 | myosin, light chain 9, regulatory | 2.43544 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.40711 |
| TERT | telomerase reverse transcriptase | 2.4012 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.29877 |
| ZNF250 | zinc finger protein 250 | 2.23309 |
| NVL | nuclear VCP-like | 2.22822 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | 2.18198 |
| METTL4 | methyltransferase like 4 | 2.16073 |
| LRRC61 | leucine rich repeat containing 61 | 2.13706 |
| CD96 | CD96 molecule | 2.13557 |
| MEST | mesoderm specific transcript | 2.10168 |
| GDF7 | growth differentiation factor 7 | 2.08729 |
| TMEM39B | transmembrane protein 39B | 2.06977 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.05114 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 2.02278 |
| ZNF239 | zinc finger protein 239 | 2.0193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GDF15 | growth differentiation factor 15 | -6.72013 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -5.05946 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.97653 |
| CDC25B | cell division cycle 25B | -4.96217 |
| MSMO1 | methylsterol monooxygenase 1 | -4.54591 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.98309 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.87129 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -3.24977 |
| SMC1A | structural maintenance of chromosomes 1A | -3.12895 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.06792 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.93159 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.60788 |
| TMEM267 | transmembrane protein 267 | -2.57336 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -2.51011 |
| NRDC | nardilysin convertase | -2.50005 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.45945 |
| ITPKC | inositol-trisphosphate 3-kinase C | -2.44142 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.43215 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -2.3966 |
| PUDP | pseudouridine 5'-phosphatase | -2.30361 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -2.29555 |
| TRIM9 | tripartite motif containing 9 | -2.26832 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.26626 |
| PITPNA | phosphatidylinositol transfer protein, alpha | -2.24245 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -2.19846 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -2.16466 |
| CAPNS1 | calpain, small subunit 1 | -2.11976 |
| UBE4A | ubiquitination factor E4A | -2.10232 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -2.09939 |
| LGALS7B | lectin, galactoside-binding, soluble, 7B | -2.07101 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -2.0525 |
| ZFHX4 | zinc finger homeobox 4 | -2.0072 |
