CRCGN016_MCF10A.WT.HP_24H:O06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 5.12282
CNPY3 canopy FGF signaling regulator 3 3.85897
SNAP25 synaptosomal-associated protein, 25kDa 3.46475
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 3.11225
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.9407
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.68678
ZNF395 zinc finger protein 395 2.5621
STK10 serine/threonine kinase 10 2.33415
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.26169
FRS2 fibroblast growth factor receptor substrate 2 2.23866
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.10181
GTPBP3 GTP binding protein 3 (mitochondrial) 2.09871
RUVBL1 RuvB-like AAA ATPase 1 2.00489

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -4.55306
GDF15 growth differentiation factor 15 -4.29194
BASP1 brain abundant, membrane attached signal protein 1 -3.54146
TUBB6 tubulin, beta 6 class V -3.16163
MSMO1 methylsterol monooxygenase 1 -2.91698
ACAA1 acetyl-CoA acyltransferase 1 -2.90463
STXBP2 syntaxin binding protein 2 -2.54184
SQSTM1 sequestosome 1 -2.38075
CXCL6 chemokine (C-X-C motif) ligand 6 -2.22717
UNC50 unc-50 homolog (C. elegans) -2.20164
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.16618
PFN1 profilin 1 -2.1577
ALDOC aldolase C, fructose-bisphosphate -2.08197