| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | BRD-K61463582 32.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STK10 | serine/threonine kinase 10 | 4.48482 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.46 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.74026 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.69596 |
| STIMATE | STIM activating enhancer | 3.53428 |
| ZW10 | zw10 kinetochore protein | 3.2608 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.22501 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.14108 |
| BAX | BCL2-associated X protein | 3.10017 |
| GLOD4 | glyoxalase domain containing 4 | 2.8843 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 2.77609 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 2.48394 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.47691 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 2.39705 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.36355 |
| MUC1 | mucin 1, cell surface associated | 2.36299 |
| SH3GL1 | SH3-domain GRB2-like 1 | 2.29465 |
| THBS2 | thrombospondin 2 | 2.23573 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.2172 |
| ACSM2A | acyl-CoA synthetase medium-chain family member 2A | 2.18765 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 2.143 |
| HTRA1 | HtrA serine peptidase 1 | 2.12413 |
| CD53 | CD53 molecule | 2.11493 |
| IER5 | immediate early response 5 | 2.10885 |
| MYL9 | myosin, light chain 9, regulatory | 2.10126 |
| TP53I3 | tumor protein p53 inducible protein 3 | 2.0976 |
| ANKRD6 | ankyrin repeat domain 6 | 2.08417 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | 2.08278 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 | 2.0374 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 2.03373 |
| FTCD | formimidoyltransferase cyclodeaminase | 2.03288 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.03132 |
| SMIM5 | small integral membrane protein 5 | 2.02853 |
| RIN3 | Ras and Rab interactor 3 | 2.02746 |
| UPB1 | ureidopropionase, beta | 2.02157 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.02148 |
| CAPN15 | calpain 15 | 2.01627 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.00757 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BASP1 | brain abundant, membrane attached signal protein 1 | -4.89321 |
| THAP11 | THAP domain containing 11 | -4.30714 |
| TXNDC9 | thioredoxin domain containing 9 | -4.26382 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.20068 |
| HSPA8 | heat shock 70kDa protein 8 | -4.1207 |
| ANXA2 | annexin A2 | -3.5235 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -3.19759 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.96519 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.95355 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.8745 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.8439 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -2.8144 |
| CLTC | clathrin, heavy chain (Hc) | -2.59061 |
| MELK | maternal embryonic leucine zipper kinase | -2.5606 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.35308 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.32989 |
| CCNB2 | cyclin B2 | -2.29645 |
| F8 | coagulation factor VIII, procoagulant component | -2.22796 |
| VDAC1 | voltage-dependent anion channel 1 | -2.2199 |
| ASF1A | anti-silencing function 1A histone chaperone | -2.20914 |
| RPS5 | ribosomal protein S5 | -2.1939 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.15874 |
| TSC22D1 | TSC22 domain family, member 1 | -2.11053 |
| CRTAP | cartilage associated protein | -2.09535 |
| REPIN1 | replication initiator 1 | -2.08739 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -2.0699 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.06186 |
| MUC7 | mucin 7, secreted | -2.02949 |
| LAGE3 | L antigen family, member 3 | -2.02243 |
| RPL21 | ribosomal protein L21 | -2.02184 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) | -2.01545 |
| KIF20A | kinesin family member 20A | -2.0104 |
