CRCGN016_MCF10A.WT.HP_24H:O14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description progesterone 32.21 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

528 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.70532
LRP10 low density lipoprotein receptor-related protein 10 6.00005
FHL2 four and a half LIM domains 2 5.92438
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5.75055
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 5.08762
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.97443
SYNGAP1 synaptic Ras GTPase activating protein 1 4.96622
NCK2 NCK adaptor protein 2 4.51357
SQOR sulfide quinone oxidoreductase 4.50734
C2CD2 C2 calcium-dependent domain containing 2 4.5047
CHIC2 cysteine-rich hydrophobic domain 2 4.46361
GLRX glutaredoxin (thioltransferase) 4.45448
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.38723
DUSP4 dual specificity phosphatase 4 4.18462
EPN2 epsin 2 4.10904
IL1B interleukin 1, beta 4.08929
S100A4 S100 calcium binding protein A4 3.92254
MAMLD1 mastermind-like domain containing 1 3.7936
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.76319
NUCB2 nucleobindin 2 3.6901
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.67519
ADAM10 ADAM metallopeptidase domain 10 3.65923
MMP1 matrix metallopeptidase 1 3.65258
NPAS2 neuronal PAS domain protein 2 3.53074
ITGB5 integrin, beta 5 3.51546
IL4R interleukin 4 receptor 3.48221
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.41168
LAGE3 L antigen family, member 3 3.35979
DUSP6 dual specificity phosphatase 6 3.35046
STX1A syntaxin 1A (brain) 3.32088
IER3 immediate early response 3 3.30273
MINDY1 MINDY lysine 48 deubiquitinase 1 3.20604
STX4 syntaxin 4 3.18851
SFXN3 sideroflexin 3 3.17883
IL1A interleukin 1, alpha 3.1487
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 3.13181
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 3.1233
AGR2 anterior gradient 2 3.12173
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3.07331
MBOAT2 membrane bound O-acyltransferase domain containing 2 3.04341
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.02062
TRIB1 tribbles pseudokinase 1 3.01405
NT5E 5'-nucleotidase, ecto (CD73) 3.00991
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.98079
RAP1GAP RAP1 GTPase activating protein 2.97942
LGMN legumain 2.97869
HMGA2 high mobility group AT-hook 2 2.95735
TICAM1 toll-like receptor adaptor molecule 1 2.92914
VAT1 vesicle amine transport 1 2.90369
STAMBP STAM binding protein 2.89268
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.84191
FAM50A family with sequence similarity 50, member A 2.75521
FAM114A1 family with sequence similarity 114, member A1 2.75067
STXBP2 syntaxin binding protein 2 2.74533
ITGB6 integrin, beta 6 2.73897
USO1 USO1 vesicle transport factor 2.72813
TMEM40 transmembrane protein 40 2.70579
ITGAV integrin, alpha V 2.69343
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.69159
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.69102
WNT7A wingless-type MMTV integration site family, member 7A 2.68818
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.67412
ZNF185 zinc finger protein 185 (LIM domain) 2.67358
SLC67A1 solute carrier family 67 member 1 2.67117
MTMR11 myotubularin related protein 11 2.63029
PYGB phosphorylase, glycogen; brain 2.62713
DAAM1 dishevelled associated activator of morphogenesis 1 2.62154
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.59661
MBNL2 muscleblind-like splicing regulator 2 2.58339
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.57624
ITPRID2 ITPR interacting domain containing 2 2.57151
G0S2 G0/G1 switch 2 2.57112
S100A12 S100 calcium binding protein A12 2.56938
LAMC2 laminin, gamma 2 2.54909
QPCT glutaminyl-peptide cyclotransferase 2.54875
ADGRG6 adhesion G protein-coupled receptor G6 2.54572
CCDC92 coiled-coil domain containing 92 2.54393
CCS copper chaperone for superoxide dismutase 2.53824
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.51914
GATA3 GATA binding protein 3 2.51857
DYNLT3 dynein, light chain, Tctex-type 3 2.51518
NRIP1 nuclear receptor interacting protein 1 2.5124
VEGFC vascular endothelial growth factor C 2.50935
NIT1 nitrilase 1 2.5073
MVP major vault protein 2.50489
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.49644
DNASE1L1 deoxyribonuclease I-like 1 2.49405
RHOC ras homolog family member C 2.4893
PPARG peroxisome proliferator-activated receptor gamma 2.4883
ATOSB atos homolog B 2.48825
CSNK1E casein kinase 1, epsilon 2.45705
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.42717
EGR3 early growth response 3 2.42078
SLC16A4 solute carrier family 16, member 4 2.41816
KIF13B kinesin family member 13B 2.41247
PLAU plasminogen activator, urokinase 2.4092
CDCP1 CUB domain containing protein 1 2.4071
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.40025
TGFBI transforming growth factor, beta-induced, 68kDa 2.39747
KIFC3 kinesin family member C3 2.38451
EPHA2 EPH receptor A2 2.38248
PORCN porcupine homolog (Drosophila) 2.37883
SKIC2 SKI2 subunit of superkiller complex 2.37569
YPEL5 yippee-like 5 (Drosophila) 2.37418
GCC2 GRIP and coiled-coil domain containing 2 2.35739
SIL1 SIL1 nucleotide exchange factor 2.35311
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.3473
IGF1R insulin-like growth factor 1 receptor 2.34712
PLS1 plastin 1 2.3374
NLRX1 NLR family member X1 2.33704
LTBP1 latent transforming growth factor beta binding protein 1 2.33624
AHNAK2 AHNAK nucleoprotein 2 2.33348
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.3282
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.32744
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 2.32345
PTHLH parathyroid hormone-like hormone 2.31849
TSG101 tumor susceptibility 101 2.31715
PDZK1IP1 PDZK1 interacting protein 1 2.3089
PLCD1 phospholipase C, delta 1 2.30786
TRIOBP TRIO and F-actin binding protein 2.30621
HBEGF heparin-binding EGF-like growth factor 2.30465
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.3037
TAOK3 TAO kinase 3 2.29302
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.29084
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.28717
MSRA methionine sulfoxide reductase A 2.28032
FNDC4 fibronectin type III domain containing 4 2.27818
ILK integrin-linked kinase 2.27616
SLK STE20-like kinase 2.25896
MACF1 microtubule-actin crosslinking factor 1 2.25598
NAGK N-acetylglucosamine kinase 2.25007
CAMTA2 calmodulin binding transcription activator 2 2.24321
MYO18A myosin XVIIIA 2.2352
ALAS1 5'-aminolevulinate synthase 1 2.23459
USP9X ubiquitin specific peptidase 9, X-linked 2.23388
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.23131
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.21831
LAMB3 laminin, beta 3 2.21796
KLHDC2 kelch domain containing 2 2.21507
UPK1B uroplakin 1B 2.21179
RALB v-ral simian leukemia viral oncogene homolog B 2.19844
CDSN corneodesmosin 2.19574
STXBP1 syntaxin binding protein 1 2.19546
SMAD3 SMAD family member 3 2.19193
PDGFA platelet-derived growth factor alpha polypeptide 2.19051
TFPI2 tissue factor pathway inhibitor 2 2.18448
BDKRB2 bradykinin receptor B2 2.17431
LIF leukemia inhibitory factor 2.17134
PROS1 protein S (alpha) 2.1691
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.16397
RASAL1 RAS protein activator like 1 (GAP1 like) 2.16068
STAP2 signal transducing adaptor family member 2 2.15292
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.14495
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.14449
FN1 fibronectin 1 2.13525
ERCC1 excision repair cross-complementation group 1 2.12841
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 2.12318
CSRP1 cysteine and glycine-rich protein 1 2.11945
POF1B premature ovarian failure, 1B 2.11601
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 2.11588
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.10792
FGD6 FYVE, RhoGEF and PH domain containing 6 2.10622
TUBG2 tubulin, gamma 2 2.10249
PRAF2 PRA1 domain family, member 2 2.10176
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.1002
RRAS related RAS viral (r-ras) oncogene homolog 2.09293
MINDY2 MINDY lysine 48 deubiquitinase 2 2.09061
PLAUR plasminogen activator, urokinase receptor 2.08929
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.08729
AVPI1 arginine vasopressin-induced 1 2.08345
GPR153 G protein-coupled receptor 153 2.08208
LARP6 La ribonucleoprotein domain family, member 6 2.08029
CDK7 cyclin-dependent kinase 7 2.07715
ZNF365 zinc finger protein 365 2.06101
CBR3 carbonyl reductase 3 2.05753
INF2 inverted formin, FH2 and WH2 domain containing 2.05718
FAM131A family with sequence similarity 131, member A 2.05702
ANO1 anoctamin 1, calcium activated chloride channel 2.05197
PDLIM4 PDZ and LIM domain 4 2.05117
ANO10 anoctamin 10 2.04877
MAGED1 melanoma antigen family D1 2.03964
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.03834
PLEK2 pleckstrin 2 2.03634
MAGED2 melanoma antigen family D2 2.03468
FSTL1 follistatin-like 1 2.03342
CHMP7 charged multivesicular body protein 7 2.03061
TPCN1 two pore segment channel 1 2.02973
KYNU kynureninase 2.02428
GPR137B G protein-coupled receptor 137B 2.01756
FURIN furin (paired basic amino acid cleaving enzyme) 2.01643
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.01486
TECPR2 tectonin beta-propeller repeat containing 2 2.01466
PYCARD PYD and CARD domain containing 2.00872
WDR44 WD repeat domain 44 2.0036
IL36RN interleukin 36 receptor antagonist 2.00183
SYT17 synaptotagmin XVII 2.00092

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -7.08017
CDK4 cyclin-dependent kinase 4 -5.80081
GADD45B growth arrest and DNA-damage-inducible, beta -5.2632
TSC22D3 TSC22 domain family, member 3 -5.15422
ADRB2 adrenoceptor beta 2, surface -5.14314
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.03436
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.9138
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.85353
LBR lamin B receptor -4.79653
UBE2C ubiquitin-conjugating enzyme E2C -4.66112
MCM3 minichromosome maintenance complex component 3 -4.63871
THAP11 THAP domain containing 11 -4.6262
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.52517
CDC45 cell division cycle 45 -4.35043
PCNA proliferating cell nuclear antigen -4.33119
KIF14 kinesin family member 14 -4.21065
C1QBP complement component 1, q subcomponent binding protein -4.16684
WDR77 WD repeat domain 77 -3.9993
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.94258
CCDC86 coiled-coil domain containing 86 -3.91496
FAIM Fas apoptotic inhibitory molecule -3.79658
UFM1 ubiquitin-fold modifier 1 -3.76495
PRR15L proline rich 15-like -3.75133
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.66514
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.6442
MCM7 minichromosome maintenance complex component 7 -3.63865
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.56578
CYCS cytochrome c, somatic -3.48959
DSCC1 DNA replication and sister chromatid cohesion 1 -3.43236
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -3.4239
NLRP2B NLR family pyrin domain containing 2B -3.40607
DCK deoxycytidine kinase -3.40438
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.39874
RPUSD2 RNA pseudouridylate synthase domain containing 2 -3.39808
OIP5 Opa interacting protein 5 -3.39132
BIRC5 baculoviral IAP repeat containing 5 -3.37549
CENPM centromere protein M -3.35067
LDHD lactate dehydrogenase D -3.32124
TLK2 tousled-like kinase 2 -3.31161
FEN1 flap structure-specific endonuclease 1 -3.30709
CDC6 cell division cycle 6 -3.30305
PUS7 pseudouridylate synthase 7 (putative) -3.30259
TMEM109 transmembrane protein 109 -3.30017
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.28292
NAT10 N-acetyltransferase 10 (GCN5-related) -3.27277
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.26531
GMNN geminin, DNA replication inhibitor -3.227
PSRC1 proline/serine-rich coiled-coil 1 -3.21189
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.18795
IPO4 importin 4 -3.18607
LMNB1 lamin B1 -3.17745
TLCD3A TLC domain containing 3A -3.17139
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.16509
PUS1 pseudouridylate synthase 1 -3.11434
MTERF3 mitochondrial transcription termination factor 3 -3.09905
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.08712
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -3.08332
RFC3 replication factor C (activator 1) 3, 38kDa -3.07147
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.06288
ILF2 interleukin enhancer binding factor 2 -3.04981
FOXM1 forkhead box M1 -3.0476
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.04455
NCAPD2 non-SMC condensin I complex, subunit D2 -3.03996
MCM10 minichromosome maintenance complex component 10 -3.0348
PLK1 polo-like kinase 1 -3.02734
CDCA8 cell division cycle associated 8 -3.01331
GLOD4 glyoxalase domain containing 4 -2.99801
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.98712
NUP133 nucleoporin 133kDa -2.98478
NFIL3 nuclear factor, interleukin 3 regulated -2.98263
MRPS2 mitochondrial ribosomal protein S2 -2.97942
RAD51AP1 RAD51 associated protein 1 -2.95945
EXOSC8 exosome component 8 -2.95875
DCAF17 DDB1 and CUL4 associated factor 17 -2.94892
DNA2 DNA replication helicase/nuclease 2 -2.91874
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.90408
FKBP5 FK506 binding protein 5 -2.90236
UNG uracil-DNA glycosylase -2.89507
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.88094
CDT1 chromatin licensing and DNA replication factor 1 -2.87934
NUP85 nucleoporin 85kDa -2.87509
PARPBP PARP1 binding protein -2.86737
DBF4 DBF4 zinc finger -2.85924
TRAP1 TNF receptor-associated protein 1 -2.82433
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.80197
PGC progastricsin (pepsinogen C) -2.79991
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.79735
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -2.77425
ORC6 origin recognition complex, subunit 6 -2.77092
NUP160 nucleoporin 160kDa -2.76122
STMN1 stathmin 1 -2.7583
DPH2 DPH2 homolog (S. cerevisiae) -2.7558
FPGS folylpolyglutamate synthase -2.74097
BORA bora, aurora kinase A activator -2.71949
CDK1 cyclin-dependent kinase 1 -2.71091
CCNF cyclin F -2.70744
EMC8 ER membrane protein complex subunit 8 -2.7051
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.70012
CHKA choline kinase alpha -2.69577
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.69253
LSM12 LSM12 homolog (S. cerevisiae) -2.6883
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.68672
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.68359
ERCC6L excision repair cross-complementation group 6-like -2.67482
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.67184
METTL16 methyltransferase like 16 -2.66516
RFC2 replication factor C (activator 1) 2, 40kDa -2.637
YEATS4 YEATS domain containing 4 -2.62164
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.61427
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.60631
TRAIP TRAF interacting protein -2.59745
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.59711
RAN RAN, member RAS oncogene family -2.58995
PRPF4 pre-mRNA processing factor 4 -2.58824
PRPF31 pre-mRNA processing factor 31 -2.57919
TATDN2 TatD DNase domain containing 2 -2.5789
FXN frataxin -2.57532
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.57488
SNRPE small nuclear ribonucleoprotein polypeptide E -2.5725
RPIA ribose 5-phosphate isomerase A -2.56976
DSN1 DSN1, MIS12 kinetochore complex component -2.56782
PRMT1 protein arginine methyltransferase 1 -2.56492
MYNN myoneurin -2.56418
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.56157
CENPN centromere protein N -2.56154
TEDC2 tubulin epsilon and delta complex 2 -2.55615
ZNF551 zinc finger protein 551 -2.55379
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.54317
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.53793
SRSF3 serine/arginine-rich splicing factor 3 -2.53736
BZW2 basic leucine zipper and W2 domains 2 -2.53298
THAP12 THAP domain containing 12 -2.5245
PRCC papillary renal cell carcinoma (translocation-associated) -2.52193
TIMELESS timeless circadian clock -2.49757
CISD1 CDGSH iron sulfur domain 1 -2.49714
MRPL11 mitochondrial ribosomal protein L11 -2.49647
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.49096
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.49077
TOE1 target of EGR1, member 1 (nuclear) -2.4886
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.47226
NCLN nicalin -2.4713
ZNF669 zinc finger protein 669 -2.46248
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.45436
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.45219
PRPF19 pre-mRNA processing factor 19 -2.4477
SYBU syntabulin (syntaxin-interacting) -2.44468
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.44333
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.44149
TRIP13 thyroid hormone receptor interactor 13 -2.43807
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.43319
MEPCE methylphosphate capping enzyme -2.4327
ACOD1 aconitate decarboxylase 1 -2.42885
HADH hydroxyacyl-CoA dehydrogenase -2.42565
SLC35B1 solute carrier family 35, member B1 -2.42093
TRAPPC2L trafficking protein particle complex 2-like -2.41694
CCNB2 cyclin B2 -2.41566
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.41518
ENTR1 endosome associated trafficking regulator 1 -2.40032
FBXO5 F-box protein 5 -2.39918
ZNF263 zinc finger protein 263 -2.39643
SAE1 SUMO1 activating enzyme subunit 1 -2.39452
SRSF7 serine/arginine-rich splicing factor 7 -2.39416
WDCP WD repeat and coiled coil containing -2.3916
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.39133
RABL6 RAB, member RAS oncogene family-like 6 -2.38955
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.38902
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.38603
SINHCAF SIN3-HDAC complex associated factor -2.38537
HOXA5 homeobox A5 -2.38517
POLR1D polymerase (RNA) I polypeptide D, 16kDa -2.3816
CCNA2 cyclin A2 -2.37627
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.37494
TRA2B transformer 2 beta homolog (Drosophila) -2.37234
TEX10 testis expressed 10 -2.37035
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.36979
ZNF227 zinc finger protein 227 -2.36765
PFAS phosphoribosylformylglycinamidine synthase -2.36478
KIF15 kinesin family member 15 -2.3631
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.3613
SIVA1 SIVA1, apoptosis-inducing factor -2.3589
NOL11 nucleolar protein 11 -2.34599
ASF1B anti-silencing function 1B histone chaperone -2.33723
TSPAN4 tetraspanin 4 -2.33549
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.33404
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.33267
TRIM28 tripartite motif containing 28 -2.33129
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.32704
ANKRD49 ankyrin repeat domain 49 -2.32486
AURKB aurora kinase B -2.32271
ABT1 activator of basal transcription 1 -2.31887
MTA2 metastasis associated 1 family, member 2 -2.31884
SFMBT1 Scm-like with four mbt domains 1 -2.31857
NOP14 NOP14 nucleolar protein -2.31824
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.31776
U2AF2 U2 small nuclear RNA auxiliary factor 2 -2.31655
EXO1 exonuclease 1 -2.31421
TP53 tumor protein p53 -2.3128
FANCI Fanconi anemia, complementation group I -2.31262
ZNF473 zinc finger protein 473 -2.312
HSPE1 heat shock 10kDa protein 1 -2.3086
GLUL glutamate-ammonia ligase -2.30109
NOP16 NOP16 nucleolar protein -2.29935
TMPO thymopoietin -2.29693
HMGB2 high mobility group box 2 -2.29322
RNASE7 ribonuclease, RNase A family, 7 -2.28947
SNRPF small nuclear ribonucleoprotein polypeptide F -2.28771
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.28339
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.28208
ZNF134 zinc finger protein 134 -2.27894
CPAP centrosome assembly and centriole elongation protein -2.2738
CHEK1 checkpoint kinase 1 -2.26605
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.25613
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -2.25538
SRRT serrate, RNA effector molecule -2.25104
SESN1 sestrin 1 -2.25028
THUMPD2 THUMP domain containing 2 -2.2461
WDR12 WD repeat domain 12 -2.24601
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.23724
THOP1 thimet oligopeptidase 1 -2.2361
WDR74 WD repeat domain 74 -2.23409
AEN apoptosis enhancing nuclease -2.23352
GTPBP8 GTP-binding protein 8 (putative) -2.23315
TFDP1 transcription factor Dp-1 -2.23241
TTK TTK protein kinase -2.2297
TIPIN TIMELESS interacting protein -2.22667
ZBTB32 zinc finger and BTB domain containing 32 -2.22514
RBM15B RNA binding motif protein 15B -2.22279
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.22193
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.22106
HAUS6 HAUS augmin-like complex, subunit 6 -2.22091
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.2155
COG2 component of oligomeric golgi complex 2 -2.21248
ACTL6A actin-like 6A -2.21199
NCAPH non-SMC condensin I complex, subunit H -2.20695
HEATR3 HEAT repeat containing 3 -2.20094
HINFP histone H4 transcription factor -2.19677
DOLPP1 dolichyldiphosphatase 1 -2.19341
ANAPC1 anaphase promoting complex subunit 1 -2.19234
ZNF8 zinc finger protein 8 -2.18954
PARP2 poly (ADP-ribose) polymerase 2 -2.18261
CGRRF1 cell growth regulator with ring finger domain 1 -2.18163
LSG1 large 60S subunit nuclear export GTPase 1 -2.18081
SKA1 spindle and kinetochore associated complex subunit 1 -2.18026
SF3B4 splicing factor 3b, subunit 4, 49kDa -2.17816
PAK1IP1 PAK1 interacting protein 1 -2.17746
DDIT4 DNA-damage-inducible transcript 4 -2.17032
POLR1F RNA polymerase I subunit F -2.16616
RAD54L RAD54-like (S. cerevisiae) -2.16615
PYDC1 PYD (pyrin domain) containing 1 -2.16595
PIMREG PICALM interacting mitotic regulator -2.16346
AUNIP aurora kinase A and ninein interacting protein -2.16324
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.16229
NELFCD negative elongation factor complex member C/D -2.16158
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -2.16067
RAD51C RAD51 paralog C -2.1591
PARP1 poly (ADP-ribose) polymerase 1 -2.15698
THOC6 THO complex 6 -2.15695
ZNF180 zinc finger protein 180 -2.1562
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.15444
ZNF318 zinc finger protein 318 -2.15334
TMEM38B transmembrane protein 38B -2.15198
ACSL5 acyl-CoA synthetase long-chain family member 5 -2.14862
GEMIN2 gem (nuclear organelle) associated protein 2 -2.14792
EBNA1BP2 EBNA1 binding protein 2 -2.14417
TBC1D10C TBC1 domain family, member 10C -2.14076
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.13442
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.13273
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.13225
RANBP10 RAN binding protein 10 -2.12608
GTF2A2 general transcription factor IIA, 2, 12kDa -2.12208
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -2.11608
EIF5 eukaryotic translation initiation factor 5 -2.11437
KAT5 K(lysine) acetyltransferase 5 -2.11305
SRSF2 serine/arginine-rich splicing factor 2 -2.1095
SAP30 Sin3A-associated protein, 30kDa -2.10802
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.10712
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.10677
UTP25 UTP25 small subunit processome component -2.10617
MCM9 minichromosome maintenance complex component 9 -2.10149
ZDHHC6 zinc finger, DHHC-type containing 6 -2.10143
TMCO1 transmembrane and coiled-coil domains 1 -2.10134
RPS5 ribosomal protein S5 -2.10036
CDCA3 cell division cycle associated 3 -2.09884
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.09868
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.09594
PROSER1 proline and serine rich 1 -2.09131
PRDM4 PR domain containing 4 -2.09034
ATF5 activating transcription factor 5 -2.08882
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.08666
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.0851
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.0818
POLR1G RNA polymerase I subunit G -2.08129
TFAM transcription factor A, mitochondrial -2.08084
ZSCAN5A zinc finger and SCAN domain containing 5A -2.08006
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.07512
SPC25 SPC25, NDC80 kinetochore complex component -2.0746
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -2.07366
OTUD3 OTU deubiquitinase 3 -2.0722
MRPL12 mitochondrial ribosomal protein L12 -2.07062
DEK DEK proto-oncogene -2.0706
PTCD1 pentatricopeptide repeat domain 1 -2.06897
ARMC6 armadillo repeat containing 6 -2.06305
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.06292
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.05622
RBM14-RBM4 RBM14-RBM4 readthrough -2.05483
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.0534
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.04909
KAT8 K(lysine) acetyltransferase 8 -2.04858
NEK2 NIMA-related kinase 2 -2.04844
ZNF761 zinc finger protein 761 -2.04505
RMI1 RecQ mediated genome instability 1 -2.04353
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.04092
KIF18A kinesin family member 18A -2.03793
ZNF16 zinc finger protein 16 -2.03782
CIRBP cold inducible RNA binding protein -2.03378
REPIN1 replication initiator 1 -2.03234
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.02915
BRIX1 BRX1, biogenesis of ribosomes -2.02892
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.02778
DNAAF2 dynein, axonemal, assembly factor 2 -2.02562
TRMO tRNA methyltransferase O -2.02523
CDC7 cell division cycle 7 -2.02403
ALPL alkaline phosphatase, liver/bone/kidney -2.02064
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.01668
SPOUT1 SPOUT domain containing methyltransferase 1 -2.01451
RFXAP regulatory factor X-associated protein -2.00851
ELAC2 elaC ribonuclease Z 2 -2.00688
HIRIP3 HIRA interacting protein 3 -2.00533
NFYB nuclear transcription factor Y, beta -2.00488
MCM5 minichromosome maintenance complex component 5 -2.00418
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.00233
TROAP trophinin associated protein -2.00083