| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | progesterone 10.74 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FHL2 | four and a half LIM domains 2 | 5.56174 |
| SQOR | sulfide quinone oxidoreductase | 4.19344 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.95365 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.81101 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.70366 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 3.67487 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 3.60303 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 3.38964 |
| DUSP4 | dual specificity phosphatase 4 | 3.1661 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 3.11663 |
| IL1B | interleukin 1, beta | 3.03297 |
| DUSP6 | dual specificity phosphatase 6 | 2.80721 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.67326 |
| IER3 | immediate early response 3 | 2.5593 |
| IL4R | interleukin 4 receptor | 2.54915 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.51858 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.50254 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 2.45537 |
| AGR2 | anterior gradient 2 | 2.44031 |
| SMAD3 | SMAD family member 3 | 2.41248 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.40578 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 2.3203 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.26581 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 2.21502 |
| STAP2 | signal transducing adaptor family member 2 | 2.15215 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 2.14005 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.13394 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 2.05629 |
| NDE1 | nudE neurodevelopment protein 1 | 2.04571 |
| NUCB2 | nucleobindin 2 | 2.02848 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 2.02078 |
| STX1A | syntaxin 1A (brain) | 2.00049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF167 | ring finger protein 167 | -4.22917 |
| TSC22D3 | TSC22 domain family, member 3 | -4.17268 |
| CCNB1 | cyclin B1 | -3.76496 |
| ADRB2 | adrenoceptor beta 2, surface | -3.75435 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.67929 |
| RPA3 | replication protein A3, 14kDa | -3.24858 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -3.01599 |
| HAT1 | histone acetyltransferase 1 | -2.82771 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -2.73059 |
| ATF5 | activating transcription factor 5 | -2.64528 |
| PRR15L | proline rich 15-like | -2.58604 |
| JADE2 | jade family PHD finger 2 | -2.44243 |
| PRR5 | proline rich 5 (renal) | -2.305 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog | -2.25956 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.23179 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -2.20175 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 | -2.19589 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -2.19056 |
| RGS2 | regulator of G-protein signaling 2 | -2.18558 |
| BAD | BCL2-associated agonist of cell death | -2.17463 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.15908 |
| DCAF17 | DDB1 and CUL4 associated factor 17 | -2.14316 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -2.12878 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | -2.0835 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -2.08191 |
| ZBTB11 | zinc finger and BTB domain containing 11 | -2.06368 |
| TRIM68 | tripartite motif containing 68 | -2.05127 |
| OSR2 | odd-skipped related transciption factor 2 | -2.01825 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -2.0106 |
| TMEM109 | transmembrane protein 109 | -2.00655 |
