| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cyanazine 98.4 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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66 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HBA1 | hemoglobin, alpha 1 | 6.06472 |
| RGS2 | regulator of G-protein signaling 2 | 5.16312 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 4.08003 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 4.01282 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 3.90284 |
| FOSL1 | FOS-like antigen 1 | 3.6378 |
| HBB | hemoglobin, beta | 3.62185 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 3.07266 |
| SPAG4 | sperm associated antigen 4 | 3.01923 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.94764 |
| STX1A | syntaxin 1A (brain) | 2.90054 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 2.81335 |
| MICALL1 | MICAL-like 1 | 2.779 |
| CDK7 | cyclin-dependent kinase 7 | 2.68653 |
| DUSP4 | dual specificity phosphatase 4 | 2.65882 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 2.64016 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.62074 |
| CAB39 | calcium binding protein 39 | 2.58655 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.45548 |
| RAB21 | RAB21, member RAS oncogene family | 2.43979 |
| SQOR | sulfide quinone oxidoreductase | 2.37074 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.32568 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.23836 |
| FHL2 | four and a half LIM domains 2 | 2.21722 |
| NGLY1 | N-glycanase 1 | 2.21327 |
| SYTL2 | synaptotagmin-like 2 | 2.12642 |
| MAPK9 | mitogen-activated protein kinase 9 | 2.11977 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.11975 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.1065 |
| HOXA5 | homeobox A5 | 2.07051 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.06722 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 2.04758 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 2.03769 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.01533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -5.17648 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -4.8553 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -4.05468 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -3.84026 |
| GDF15 | growth differentiation factor 15 | -3.78591 |
| NLRP4 | NLR family, pyrin domain containing 4 | -3.40867 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -3.29293 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.97338 |
| KIF14 | kinesin family member 14 | -2.90219 |
| KEAP1 | kelch-like ECH-associated protein 1 | -2.88911 |
| ATF5 | activating transcription factor 5 | -2.87402 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.80758 |
| JADE2 | jade family PHD finger 2 | -2.67029 |
| HTRA1 | HtrA serine peptidase 1 | -2.54353 |
| COG4 | component of oligomeric golgi complex 4 | -2.52175 |
| TSC22D3 | TSC22 domain family, member 3 | -2.50972 |
| TSPAN4 | tetraspanin 4 | -2.34642 |
| INTS3 | integrator complex subunit 3 | -2.30558 |
| PHGDH | phosphoglycerate dehydrogenase | -2.30391 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | -2.26861 |
| DCAF11 | DDB1 and CUL4 associated factor 11 | -2.24996 |
| GALE | UDP-galactose-4-epimerase | -2.19998 |
| SH3D19 | SH3 domain containing 19 | -2.19917 |
| NOTCH1 | notch 1 | -2.14544 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.14056 |
| KRT14 | keratin 14, type I | -2.13374 |
| CIRBP | cold inducible RNA binding protein | -2.12563 |
| INSIG1 | insulin induced gene 1 | -2.10457 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -2.09772 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -2.09743 |
| TLCD3A | TLC domain containing 3A | -2.05269 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -2.01159 |