CRCGN016_MCF10A.WT.HP_24H:O18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyanazine 10.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
OXSR1 oxidative stress responsive 1 3.8389
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.74849
TBPL1 TBP-like 1 3.19962
HBA1 hemoglobin, alpha 1 3.02201
KLHL9 kelch-like family member 9 2.81566
CCL2 chemokine (C-C motif) ligand 2 2.42663
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.41594
CGRRF1 cell growth regulator with ring finger domain 1 2.25481
AGR2 anterior gradient 2 2.20856
GARRE1 granule associated Rac and RHOG effector 1 2.07464
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.06014
TXNL4B thioredoxin-like 4B 2.01459

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -4.34183
HMG20B high mobility group 20B -4.12544
HSPA8 heat shock 70kDa protein 8 -4.08153
ATF5 activating transcription factor 5 -2.82766
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.70888
BASP1 brain abundant, membrane attached signal protein 1 -2.6082
NPDC1 neural proliferation, differentiation and control, 1 -2.05738
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.024