CRCGN016_MCF10A.WT.HP_24H:O21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tegafur 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

523 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TLR4 toll-like receptor 4 7.10733
CDPF1 cysteine-rich, DPF motif domain containing 1 5.54446
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.57313
HBA1 hemoglobin, alpha 1 4.31642
GHR growth hormone receptor 3.95381
CHMP6 charged multivesicular body protein 6 3.89996
TBC1D10C TBC1 domain family, member 10C 3.84623
FCHO1 FCH domain only 1 3.75856
TLR8 toll-like receptor 8 3.5459
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.5027
CAPN1 calpain 1, (mu/I) large subunit 3.40395
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.37671
CD300C CD300c molecule 3.35907
TBX2 T-box 2 3.34338
PAX2 paired box 2 3.14276
FPR2 formyl peptide receptor 2 3.08673
PRR7 proline rich 7 (synaptic) 3.05973
APOBR apolipoprotein B receptor 3.04462
E2F2 E2F transcription factor 2 3.00117
HBB hemoglobin, beta 3.00014
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 2.97432
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.92891
OSTF1 osteoclast stimulating factor 1 2.88498
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.85568
TRIM66 tripartite motif containing 66 2.83469
SMAD9 SMAD family member 9 2.82556
FAM76A family with sequence similarity 76, member A 2.81469
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 2.81047
AOAH acyloxyacyl hydrolase (neutrophil) 2.8003
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.79378
PTPRC protein tyrosine phosphatase, receptor type, C 2.78626
IGSF6 immunoglobulin superfamily, member 6 2.77735
TRABD TraB domain containing 2.76634
BICDL1 BICD family like cargo adaptor 1 2.76022
ARL4C ADP-ribosylation factor-like 4C 2.75969
BAX BCL2-associated X protein 2.75902
FN3K fructosamine 3 kinase 2.73757
SOX2 SRY (sex determining region Y)-box 2 2.72603
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.71812
LYZL6 lysozyme-like 6 2.71295
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.69907
MZB1 marginal zone B and B1 cell-specific protein 2.69497
AMOT angiomotin 2.69001
MARCHF1 membrane associated ring-CH-type finger 1 2.6739
CYBB cytochrome b-245, beta polypeptide 2.67079
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.66948
TP73 tumor protein p73 2.65812
ICAM1 intercellular adhesion molecule 1 2.63877
GPR132 G protein-coupled receptor 132 2.63791
KRT32 keratin 32, type I 2.63755
HIGD1B HIG1 hypoxia inducible domain family, member 1B 2.63006
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.62624
SLC22A17 solute carrier family 22, member 17 2.62049
ANGPT4 angiopoietin 4 2.61197
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.60129
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.60061
APOL3 apolipoprotein L, 3 2.59668
AMT aminomethyltransferase 2.59622
MYO3A myosin IIIA 2.57885
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.57115
CDC25A cell division cycle 25A 2.56976
MUC1 mucin 1, cell surface associated 2.56526
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene) 2.56407
MOB3B MOB kinase activator 3B 2.56021
RGS4 regulator of G-protein signaling 4 2.55809
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.54923
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.54651
SIGLEC9 sialic acid binding Ig-like lectin 9 2.54623
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 2.54469
BEX4 brain expressed, X-linked 4 2.54435
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.53973
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.53368
MTA2 metastasis associated 1 family, member 2 2.5235
RLN2 relaxin 2 2.51991
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.50859
ZFPM2 zinc finger protein, FOG family member 2 2.50787
FAM131B family with sequence similarity 131, member B 2.5054
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.50453
PARM1 prostate androgen-regulated mucin-like protein 1 2.50361
CLEC7A C-type lectin domain family 7, member A 2.49398
KRT85 keratin 85, type II 2.48376
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.4777
ABHD8 abhydrolase domain containing 8 2.47232
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.46887
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.46534
CCNE2 cyclin E2 2.46128
NCS1 neuronal calcium sensor 1 2.45924
TEDC2 tubulin epsilon and delta complex 2 2.45908
DCN decorin 2.45821
TMEM143 transmembrane protein 143 2.44906
SEC31B SEC31 homolog B (S. cerevisiae) 2.44885
ACVR2B activin A receptor, type IIB 2.44809
DRC4 dynein regulatory complex subunit 4 2.44605
ZNF132 zinc finger protein 132 2.43948
TAS2R3 taste receptor, type 2, member 3 2.43926
CCP110 centriolar coiled coil protein 110kDa 2.43894
KLRG1 killer cell lectin-like receptor subfamily G, member 1 2.43073
RASAL1 RAS protein activator like 1 (GAP1 like) 2.42244
STIMATE STIM activating enhancer 2.41749
PCDHGA9 protocadherin gamma subfamily A, 9 2.4146
SYN3 synapsin III 2.41449
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.40887
MYOZ3 myozenin 3 2.40495
ASPN asporin 2.40351
NACAD NAC alpha domain containing 2.40331
GHRHR growth hormone releasing hormone receptor 2.4015
LHX1 LIM homeobox 1 2.40099
CD300A CD300a molecule 2.39835
TLR7 toll-like receptor 7 2.39559
C8G complement component 8, gamma polypeptide 2.39268
MARCHF2 membrane associated ring-CH-type finger 2 2.39038
TRIM46 tripartite motif containing 46 2.39003
FSD1 fibronectin type III and SPRY domain containing 1 2.37665
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 2.37567
SLCO1B1 solute carrier organic anion transporter family, member 1B1 2.37531
MAPK10 mitogen-activated protein kinase 10 2.37477
ARC activity-regulated cytoskeleton-associated protein 2.37411
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.37225
DIPK2B divergent protein kinase domain 2B 2.36874
CEPT1 choline/ethanolamine phosphotransferase 1 2.36747
ADAM20 ADAM metallopeptidase domain 20 2.36648
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.36547
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.36212
GPR27 G protein-coupled receptor 27 2.35806
ZNF671 zinc finger protein 671 2.3576
ZNF124 zinc finger protein 124 2.35682
THBS2 thrombospondin 2 2.35327
NPY4R2 neuropeptide Y receptor Y4-2 2.35308
LDAF1 lipid droplet assembly factor 1 2.34953
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 2.3482
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.3482
COL4A4 collagen, type IV, alpha 4 2.34748
FGF21 fibroblast growth factor 21 2.34413
FGL2 fibrinogen-like 2 2.34363
ELAC1 elaC ribonuclease Z 1 2.34323
SLC22A14 solute carrier family 22, member 14 2.34256
CLDN11 claudin 11 2.34058
G6PC2 glucose-6-phosphatase, catalytic, 2 2.33866
TM6SF1 transmembrane 6 superfamily member 1 2.33626
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.33162
PRR14L proline rich 14-like 2.32531
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2.32495
FBXL8 F-box and leucine-rich repeat protein 8 2.31876
CHAF1A chromatin assembly factor 1, subunit A (p150) 2.31761
SNN stannin 2.31116
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 2.30963
MMP27 matrix metallopeptidase 27 2.30456
GSTCD glutathione S-transferase, C-terminal domain containing 2.29883
CTSD cathepsin D 2.29797
FMO1 flavin containing monooxygenase 1 2.29511
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.29382
PILRA paired immunoglobin-like type 2 receptor alpha 2.29362
HOOK3 hook microtubule-tethering protein 3 2.2929
CABP5 calcium binding protein 5 2.29252
SYP synaptophysin 2.29001
DGKQ diacylglycerol kinase, theta 110kDa 2.28656
IL20RA interleukin 20 receptor, alpha 2.286
BAK1 BCL2-antagonist/killer 1 2.2835
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.28182
DRP2 dystrophin related protein 2 2.28027
HYI hydroxypyruvate isomerase (putative) 2.27755
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.27567
SYN1 synapsin I 2.27361
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.27167
SCIN scinderin 2.27152
PSKH1 protein serine kinase H1 2.27039
SEPTIN4 septin 4 2.26996
CSH2 chorionic somatomammotropin hormone 2 2.26971
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.26903
MOCS1 molybdenum cofactor synthesis 1 2.26817
WDR76 WD repeat domain 76 2.26806
MTMR10 myotubularin related protein 10 2.26505
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.26202
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.26189
DUOX2 dual oxidase 2 2.26146
EPHA3 EPH receptor A3 2.2598
GHRH growth hormone releasing hormone 2.25963
B3GAT1 beta-1,3-glucuronyltransferase 1 2.2591
CD84 CD84 molecule 2.2553
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.25508
EMILIN2 elastin microfibril interfacer 2 2.25462
RFPL2 ret finger protein-like 2 2.2531
PTPRS protein tyrosine phosphatase, receptor type, S 2.25245
DPYSL4 dihydropyrimidinase-like 4 2.25236
PACS1 phosphofurin acidic cluster sorting protein 1 2.25177
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.25143
ISYNA1 inositol-3-phosphate synthase 1 2.24873
CNTN2 contactin 2 (axonal) 2.24871
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.24757
TBR1 T-box, brain, 1 2.24605
TEX14 testis expressed 14 2.24522
ZNF835 zinc finger protein 835 2.24134
EMC10 ER membrane protein complex subunit 10 2.2386
FGD2 FYVE, RhoGEF and PH domain containing 2 2.23733
PRDM12 PR domain containing 12 2.23644
LIN7B lin-7 homolog B (C. elegans) 2.2342
LY96 lymphocyte antigen 96 2.23205
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.22376
EPHA1 EPH receptor A1 2.22357
ERLIN2 ER lipid raft associated 2 2.22316
DOC2B double C2-like domains, beta 2.22235
CNTFR ciliary neurotrophic factor receptor 2.22109
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 2.22077
KLK15 kallikrein-related peptidase 15 2.22041
SYNDIG1 synapse differentiation inducing 1 2.22017
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 2.2151
DDR1 discoidin domain receptor tyrosine kinase 1 2.21469
RASL10A RAS-like, family 10, member A 2.21329
VENTX VENT homeobox 2.21196
MEGF6 multiple EGF-like-domains 6 2.21158
ADGRG1 adhesion G protein-coupled receptor G1 2.21091
HTN3 histatin 3 2.20724
GPR176 G protein-coupled receptor 176 2.2071
VNN2 vanin 2 2.20637
OR1A2 olfactory receptor, family 1, subfamily A, member 2 2.1986
FSHR follicle stimulating hormone receptor 2.19824
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.19725
FDXR ferredoxin reductase 2.19534
CLEC4A C-type lectin domain family 4, member A 2.19381
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.1938
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.1926
CDADC1 cytidine and dCMP deaminase domain containing 1 2.19245
CD101 CD101 molecule 2.18996
EPN3 epsin 3 2.18804
MXRA5 matrix-remodelling associated 5 2.18743
GALR3 galanin receptor 3 2.1871
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.18686
SWAP70 SWAP switching B-cell complex 70kDa subunit 2.1865
DOK3 docking protein 3 2.18636
FBP1 fructose-1,6-bisphosphatase 1 2.18397
FGR FGR proto-oncogene, Src family tyrosine kinase 2.18227
NXPH3 neurexophilin 3 2.18226
EDA2R ectodysplasin A2 receptor 2.18174
EFHD1 EF-hand domain family, member D1 2.1814
C5 complement component 5 2.18062
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.17944
AIG1 androgen-induced 1 2.17933
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.17719
STK38 serine/threonine kinase 38 2.177
TMEM160 transmembrane protein 160 2.17673
IFNGR1 interferon gamma receptor 1 2.17584
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.1754
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.17257
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.17173
ADAM11 ADAM metallopeptidase domain 11 2.16962
PCDHA10 protocadherin alpha 10 2.1694
ADIRF adipogenesis regulatory factor 2.16791
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.16612
FES FES proto-oncogene, tyrosine kinase 2.16429
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.16426
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.16421
OR12D3 olfactory receptor, family 12, subfamily D, member 3 2.16414
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.16098
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.15941
LOC107987479 cytochrome P450 2D6 2.15872
CDX4 caudal type homeobox 4 2.15774
MDM4 MDM4, p53 regulator 2.15643
PMFBP1 polyamine modulated factor 1 binding protein 1 2.15615
TLR1 toll-like receptor 1 2.1556
SIX6 SIX homeobox 6 2.15441
CD1E CD1e molecule 2.15408
GJA5 gap junction protein, alpha 5, 40kDa 2.1537
APCS amyloid P component, serum 2.1535
LRRC40 leucine rich repeat containing 40 2.15333
CALCRL calcitonin receptor-like 2.15198
TRIM22 tripartite motif containing 22 2.15112
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.15013
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.1484
IL12RB1 interleukin 12 receptor, beta 1 2.13893
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.1388
ALOX5 arachidonate 5-lipoxygenase 2.13782
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.13767
SFXN1 sideroflexin 1 2.13724
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.13679
ERBB4 erb-b2 receptor tyrosine kinase 4 2.13348
ZNF804A zinc finger protein 804A 2.13324
LOC124900193 uncharacterized LOC124900193 2.13308
FECH ferrochelatase 2.13246
LYN LYN proto-oncogene, Src family tyrosine kinase 2.13055
OXT oxytocin/neurophysin I prepropeptide 2.12771
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.1277
KLHL35 kelch-like family member 35 2.12766
CLDN14 claudin 14 2.12642
NPAP1 nuclear pore associated protein 1 2.12531
PTPRU protein tyrosine phosphatase, receptor type, U 2.12507
E2F1 E2F transcription factor 1 2.12332
EMCN endomucin 2.12247
OLFML1 olfactomedin-like 1 2.12123
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 2.11889
JCHAIN joining chain of multimeric IgA and IgM 2.11888
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.11853
CXCR1 chemokine (C-X-C motif) receptor 1 2.11777
ZNF415 zinc finger protein 415 2.11752
DNAAF8 dynein axonemal assembly factor 8 2.11683
ZNF221 zinc finger protein 221 2.11603
GUCY2F guanylate cyclase 2F, retinal 2.11537
LOC102724023 ES1 protein homolog, mitochondrial 2.11505
S1PR5 sphingosine-1-phosphate receptor 5 2.11437
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 2.11347
NGB neuroglobin 2.11126
INSRR insulin receptor-related receptor 2.10964
CDC45 cell division cycle 45 2.10827
ACVRL1 activin A receptor type II-like 1 2.10734
FGF7 fibroblast growth factor 7 2.10679
BMP7 bone morphogenetic protein 7 2.10611
POLM polymerase (DNA directed), mu 2.10564
CHRM4 cholinergic receptor, muscarinic 4 2.10562
ZNF219 zinc finger protein 219 2.10537
MYCT1 myc target 1 2.10463
ARL15 ADP-ribosylation factor-like 15 2.10415
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.1034
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.10227
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.10213
GCGR glucagon receptor 2.10195
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.10114
HELLS helicase, lymphoid-specific 2.10063
FANCF Fanconi anemia, complementation group F 2.10034
AVPR1B arginine vasopressin receptor 1B 2.09982
NT5DC2 5'-nucleotidase domain containing 2 2.09958
MYO15A myosin XVA 2.09949
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 2.09612
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2.09513
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 2.09425
KIF26B kinesin family member 26B 2.09258
KRT83 keratin 83, type II 2.09118
FOXE3 forkhead box E3 2.09045
TMEM223 transmembrane protein 223 2.0901
DCAF1 DDB1 and CUL4 associated factor 1 2.08969
HOXA6 homeobox A6 2.08912
PARD6A par-6 family cell polarity regulator alpha 2.08809
RIC3 RIC3 acetylcholine receptor chaperone 2.0875
CAPN5 calpain 5 2.08669
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 2.08604
PRDM11 PR domain containing 11 2.08523
MUC2 mucin 2, oligomeric mucus/gel-forming 2.08521
NEUROD2 neuronal differentiation 2 2.08506
PYHIN1 pyrin and HIN domain family, member 1 2.08387
FMO3 flavin containing monooxygenase 3 2.08353
MNDA myeloid cell nuclear differentiation antigen 2.08335
PAX1 paired box 1 2.08283
RGS16 regulator of G-protein signaling 16 2.08102
INTS1 integrator complex subunit 1 2.07842
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 2.07629
SH2B2 SH2B adaptor protein 2 2.07589
ADM2 adrenomedullin 2 2.07423
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.07421
OVOL1 ovo-like zinc finger 1 2.07352
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 2.07225
LOC124906280 uncharacterized LOC124906280 2.07188
GGT5 gamma-glutamyltransferase 5 2.07183
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.07032
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 2.06915
PITPNM3 PITPNM family member 3 2.06834
NOTCH4 notch 4 2.06662
GPR31 G protein-coupled receptor 31 2.06652
CCR2 chemokine (C-C motif) receptor 2 2.06644
PAX8 paired box 8 2.06633
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 2.06591
IMPG2 interphotoreceptor matrix proteoglycan 2 2.06577
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.06244
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.06217
IL25 interleukin 25 2.06209
MSR1 macrophage scavenger receptor 1 2.06197
WNT2 wingless-type MMTV integration site family member 2 2.06046
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.05805
STX12 syntaxin 12 2.05738
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 2.05709
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 2.05575
FFAR3 free fatty acid receptor 3 2.05559
ZNF154 zinc finger protein 154 2.05493
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.05477
CEL carboxyl ester lipase 2.05401
SH2D3C SH2 domain containing 3C 2.05275
H2AP H2A.P histone 2.04934
CCDC33 coiled-coil domain containing 33 2.04881
NCR2 natural cytotoxicity triggering receptor 2 2.04496
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.04431
NLRP3 NLR family, pyrin domain containing 3 2.04411
SALL2 spalt-like transcription factor 2 2.04333
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.03961
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 2.0396
PRODH proline dehydrogenase (oxidase) 1 2.03939
ROGDI rogdi homolog (Drosophila) 2.03888
CARD14 caspase recruitment domain family, member 14 2.03861
OVOL3 ovo-like zinc finger 3 2.03855
MTNR1A melatonin receptor 1A 2.03832
RRH retinal pigment epithelium-derived rhodopsin homolog 2.038
NCAPH2 non-SMC condensin II complex, subunit H2 2.03558
FILIP1L filamin A interacting protein 1-like 2.03542
CHRM5 cholinergic receptor, muscarinic 5 2.03533
RFPL3 ret finger protein-like 3 2.0352
SGSM3 small G protein signaling modulator 3 2.03351
INCENP inner centromere protein antigens 135/155kDa 2.03343
CNTNAP3B contactin associated protein-like 3B 2.03291
KRT35 keratin 35, type I 2.03268
RFX2 regulatory factor X, 2 (influences HLA class II expression) 2.03166
CDT1 chromatin licensing and DNA replication factor 1 2.03155
MGAM2 maltase-glucoamylase 2 (putative) 2.02954
MRLN myoregulin 2.02945
TULP2 tubby like protein 2 2.02797
CRYBB1 crystallin, beta B1 2.02765
NPDC1 neural proliferation, differentiation and control, 1 2.02738
ELL3 elongation factor RNA polymerase II-like 3 2.02598
TLR6 toll-like receptor 6 2.02456
KANK3 KN motif and ankyrin repeat domains 3 2.02175
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.02173
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.02052
PELI1 pellino E3 ubiquitin protein ligase 1 2.01993
OCM2 oncomodulin 2 2.01933
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.01835
LOC100652777 group 10 secretory phospholipase A2-like 2.01716
GRIA4 glutamate receptor, ionotropic, AMPA 4 2.0171
ZNF528 zinc finger protein 528 2.01702
HHLA1 HERV-H LTR-associating 1 2.01519
PTK2B protein tyrosine kinase 2 beta 2.01441
CTSO cathepsin O 2.01425
HPX hemopexin 2.01407
RNF115 ring finger protein 115 2.01402
RADX RPA1 related single stranded DNA binding protein, X-linked 2.01389
KIAA0319L KIAA0319-like 2.01313
MCPH1 microcephalin 1 2.01311
HRK harakiri, BCL2 interacting protein 2.01225
POM121 POM121 transmembrane nucleoporin 2.01111
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.01095
CD1B CD1b molecule 2.0109
CENPO centromere protein O 2.01026
HOXB2 homeobox B2 2.00971
CPLX3 complexin 3 2.00949
NMBR neuromedin B receptor 2.00629
MYL2 myosin, light chain 2, regulatory, cardiac, slow 2.00628
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 2.00605
OPRL1 opiate receptor-like 1 2.00602
GCAT glycine C-acetyltransferase 2.00563
STMN3 stathmin-like 3 2.00542
CDIP1 cell death-inducing p53 target 1 2.00537
WNT3 wingless-type MMTV integration site family, member 3 2.00349
RAP1GAP RAP1 GTPase activating protein 2.00311
FRMPD4 FERM and PDZ domain containing 4 2.00271
TCEA2 transcription elongation factor A (SII), 2 2.00225
SIGLEC7 sialic acid binding Ig-like lectin 7 2.00187
H4C7 H4 clustered histone 7 2.00004

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -8.01705
BASP1 brain abundant, membrane attached signal protein 1 -7.39613
KIF20A kinesin family member 20A -6.64178
KIF14 kinesin family member 14 -5.69183
CDC20 cell division cycle 20 -5.5886
NCAPD2 non-SMC condensin I complex, subunit D2 -5.4037
PSRC1 proline/serine-rich coiled-coil 1 -5.35163
TOP2A topoisomerase (DNA) II alpha 170kDa -4.92491
AURKA aurora kinase A -4.59443
KDM3A lysine (K)-specific demethylase 3A -4.54337
PLK1 polo-like kinase 1 -4.43861
CAB39 calcium binding protein 39 -4.1311
VAT1 vesicle amine transport 1 -4.0198
CRTAP cartilage associated protein -3.99127
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.56922
CCNB2 cyclin B2 -3.54519
TMEM147 transmembrane protein 147 -3.54073
KIF4A kinesin family member 4A -3.4113
THAP11 THAP domain containing 11 -3.29085
HJURP Holliday junction recognition protein -3.27824
CDKN3 cyclin-dependent kinase inhibitor 3 -3.23795
LBR lamin B receptor -3.22706
CDCA3 cell division cycle associated 3 -3.20643
CCNA2 cyclin A2 -3.20388
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -3.15689
PCCB propionyl CoA carboxylase, beta polypeptide -3.13715
TPX2 TPX2, microtubule-associated -3.13029
TBCB tubulin folding cofactor B -3.08587
SYNGAP1 synaptic Ras GTPase activating protein 1 -2.97002
CENPA centromere protein A -2.89254
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.85539
CDC25B cell division cycle 25B -2.79687
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.69183
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.56527
CLTC clathrin, heavy chain (Hc) -2.55274
LOC112694756 uncharaterized LOC112694756 -2.55244
CKAP5 cytoskeleton associated protein 5 -2.5435
ANAPC1 anaphase promoting complex subunit 1 -2.54081
PDCD5 programmed cell death 5 -2.48441
TMEM185B transmembrane protein 185B -2.48214
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.46274
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.44259
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.43895
TRIP12 thyroid hormone receptor interactor 12 -2.43432
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.40714
TSC22D1 TSC22 domain family, member 1 -2.4071
AURKB aurora kinase B -2.37416
WDR12 WD repeat domain 12 -2.36475
RBM42 RNA binding motif protein 42 -2.36409
RACGAP1 Rac GTPase activating protein 1 -2.3616
NCBP2 nuclear cap binding protein subunit 2, 20kDa -2.35759
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.34196
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.33776
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.33178
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.31817
KCTD5 potassium channel tetramerization domain containing 5 -2.28738
CAPN7 calpain 7 -2.25932
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.23935
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.23371
TSKU tsukushi, small leucine rich proteoglycan -2.23262
RRAGA Ras-related GTP binding A -2.22942
STAMBP STAM binding protein -2.21427
RPN2 ribophorin II -2.19727
MIDEAS mitotic deacetylase associated SANT domain protein -2.19192
GRWD1 glutamate-rich WD repeat containing 1 -2.19024
SKIC2 SKI2 subunit of superkiller complex -2.15902
ZNF146 zinc finger protein 146 -2.15467
TOMM34 translocase of outer mitochondrial membrane 34 -2.12966
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.11184
TACC3 transforming, acidic coiled-coil containing protein 3 -2.11117
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.10113
DYNLL1 dynein, light chain, LC8-type 1 -2.08419
TCERG1 transcription elongation regulator 1 -2.06128
NGRN neugrin, neurite outgrowth associated -2.04131
DYNLRB1 dynein, light chain, roadblock-type 1 -2.0327
TTK TTK protein kinase -2.02902
SEC13 SEC13 homolog (S. cerevisiae) -2.02176
UBE3C ubiquitin protein ligase E3C -2.02086
TGFBI transforming growth factor, beta-induced, 68kDa -2.01917
NNT nicotinamide nucleotide transhydrogenase -2.01694
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.01517
GPATCH1 G patch domain containing 1 -2.0066