CRCGN016_MCF10A.WT.HP_24H:P04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benz(a)anthracene 100.17 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

70 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.65909
AMDHD2 amidohydrolase domain containing 2 4.35082
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.80864
CNPY3 canopy FGF signaling regulator 3 3.76078
ADRB2 adrenoceptor beta 2, surface 3.7525
KIF5C kinesin family member 5C 3.65678
ACAA1 acetyl-CoA acyltransferase 1 3.1669
MSRA methionine sulfoxide reductase A 3.09809
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.85612
TPD52L2 tumor protein D52-like 2 2.77757
SPRED2 sprouty-related, EVH1 domain containing 2 2.75773
NVL nuclear VCP-like 2.58439
EMX2 empty spiracles homeobox 2 2.58159
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.51648
PHF13 PHD finger protein 13 2.48152
SSTR5 somatostatin receptor 5 2.47068
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.43158
APOA4 apolipoprotein A-IV 2.36212
TBL3 transducin (beta)-like 3 2.36192
MDM4 MDM4, p53 regulator 2.36174
VRTN vertebrae development associated 2.35047
MOB3B MOB kinase activator 3B 2.34091
ARMC1 armadillo repeat containing 1 2.29988
APOA1 apolipoprotein A-I 2.2917
NMUR1 neuromedin U receptor 1 2.2704
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 2.26491
GAGE8 G antigen 8 2.26071
CTSA cathepsin A 2.24053
SCT secretin 2.22822
GAGE1 G antigen 1 2.20485
MELK maternal embryonic leucine zipper kinase 2.17487
CDHR2 cadherin-related family member 2 2.16521
TREH trehalase (brush-border membrane glycoprotein) 2.14895
SGF29 SAGA complex associated factor 29 2.14624
MARK1 MAP/microtubule affinity-regulating kinase 1 2.14283
TLE6 transducin-like enhancer of split 6 2.14193
CBARP CACN subunit beta associated regulatory protein 2.13983
CLEC10A C-type lectin domain family 10, member A 2.12991
EDN1 endothelin 1 2.12982
GAMT guanidinoacetate N-methyltransferase 2.12964
IL1R2 interleukin 1 receptor, type II 2.12005
OBP2B odorant binding protein 2B 2.08494
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.08143
ANK2 ankyrin 2, neuronal 2.07821
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.05771
CD2AP CD2-associated protein 2.05436
COPS5 COP9 signalosome subunit 5 2.04893
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.04287
ADORA1 adenosine A1 receptor 2.03054
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.0296
CDHR5 cadherin-related family member 5 2.02088
RAB32 RAB32, member RAS oncogene family 2.01658
EDN2 endothelin 2 2.0148
TUBA3E tubulin, alpha 3e 2.00939
CD19 CD19 molecule 2.00808
UBIAD1 UbiA prenyltransferase domain containing 1 2.00293
YEATS4 YEATS domain containing 4 2.00038

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -6.89763
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.59735
BAG3 BCL2-associated athanogene 3 -4.98303
NT5DC2 5'-nucleotidase domain containing 2 -4.95852
HAT1 histone acetyltransferase 1 -4.47246
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.2879
REEP5 receptor accessory protein 5 -2.29425
CETN3 centrin, EF-hand protein, 3 -2.23323
S100A11 S100 calcium binding protein A11 -2.17668
USP1 ubiquitin specific peptidase 1 -2.13221
ZCCHC8 zinc finger, CCHC domain containing 8 -2.04059
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.0106
LTA4H leukotriene A4 hydrolase -2.00233