CRCGN016_MCF10A.WT.HP_24H:P05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benz(a)anthracene 33.39 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 3.85221
FKBP14 FK506 binding protein 14, 22 kDa 3.55443
SYNE2 spectrin repeat containing, nuclear envelope 2 3.38643
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.19534
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.91516
KDM5A lysine (K)-specific demethylase 5A 2.86381
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.78728
TIAM1 T-cell lymphoma invasion and metastasis 1 2.54216
SQOR sulfide quinone oxidoreductase 2.49577
SV2B synaptic vesicle glycoprotein 2B 2.20458
LGI1 leucine-rich, glioma inactivated 1 2.20125
GSK3B glycogen synthase kinase 3 beta 2.04053

decreased expression

Symbol Name Standardized Value
ARID4B AT rich interactive domain 4B (RBP1-like) -3.41969
GDF15 growth differentiation factor 15 -3.30171
SGK1 serum/glucocorticoid regulated kinase 1 -3.15284
DNM1L dynamin 1-like -3.08801
S100A8 S100 calcium binding protein A8 -3.03948
RPIA ribose 5-phosphate isomerase A -3.03196
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.01304
KIF20A kinesin family member 20A -2.84856
PSIP1 PC4 and SFRS1 interacting protein 1 -2.20133
FPGS folylpolyglutamate synthase -2.01885