| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benz(a)anthracene 11.13 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 5.4178 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.95302 |
| AGR2 | anterior gradient 2 | 4.17485 |
| LGMN | legumain | 3.76683 |
| MICALL1 | MICAL-like 1 | 3.58733 |
| NSG2 | neuronal vesicle trafficking associated 2 | 3.0057 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.98984 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.94364 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.86693 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 2.72387 |
| STMN2 | stathmin 2 | 2.63345 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 2.51272 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.49737 |
| PLSCR3 | phospholipid scramblase 3 | 2.36289 |
| VPREB3 | pre-B lymphocyte 3 | 2.33747 |
| RAB23 | RAB23, member RAS oncogene family | 2.33359 |
| SYT1 | synaptotagmin I | 2.28856 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 2.20071 |
| PRELID3B | PRELI domain containing 3B | 2.19001 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 2.18687 |
| CDK17 | cyclin-dependent kinase 17 | 2.11835 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | 2.11679 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 2.10941 |
| MIURF | mitochondrial elongation factor 1 upstream open reading frame | 2.0978 |
| RBBP8 | retinoblastoma binding protein 8 | 2.06948 |
| WASF3 | WAS protein family, member 3 | 2.05796 |
| RYR3 | ryanodine receptor 3 | 2.05696 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 2.04948 |
| SPDEF | SAM pointed domain containing ETS transcription factor | 2.01948 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | 2.00943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DSG2 | desmoglein 2 | -5.16396 |
| PUF60 | poly-U binding splicing factor 60KDa | -5.10551 |
| CCNB1 | cyclin B1 | -5.01443 |
| NUP85 | nucleoporin 85kDa | -4.79525 |
| VAT1 | vesicle amine transport 1 | -4.70621 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -3.46702 |
| TMEM94 | transmembrane protein 94 | -3.41714 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.17566 |
| SAP30BP | SAP30 binding protein | -3.15802 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -3.11224 |
| MRPL58 | mitochondrial ribosomal protein L58 | -3.07217 |
| SUMO4 | small ubiquitin-like modifier 4 | -3.00936 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.95599 |
| ADI1 | acireductone dioxygenase 1 | -2.941 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.83111 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.78189 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.52333 |
| HMG20B | high mobility group 20B | -2.48098 |
| CD44 | CD44 molecule (Indian blood group) | -2.46328 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.39526 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -2.39434 |
| MRPS27 | mitochondrial ribosomal protein S27 | -2.28786 |
| PCNA | proliferating cell nuclear antigen | -2.28093 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 | -2.25032 |
| GRB2 | growth factor receptor-bound protein 2 | -2.23725 |
| LOC124907090 | ankyrin repeat domain-containing protein SOWAHC-like | -2.21191 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.21072 |
| SYT17 | synaptotagmin XVII | -2.20571 |
| RETN | resistin | -2.18285 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase | -2.16819 |
| GDF15 | growth differentiation factor 15 | -2.16175 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -2.14914 |
| HSPA8 | heat shock 70kDa protein 8 | -2.14903 |
| NVL | nuclear VCP-like | -2.11889 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -2.11398 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.11048 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -2.03336 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.02983 |
