CRCGN016_MCF10A.WT.HP_24H:P07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-toluidine.hcl 99.26 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.9245
FCHO1 FCH domain only 1 4.6402
WASF3 WAS protein family, member 3 4.49346
FGFR4 fibroblast growth factor receptor 4 4.34108
STK10 serine/threonine kinase 10 4.09114
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.93431
CARMIL1 capping protein regulator and myosin 1 linker 1 3.81109
COMP cartilage oligomeric matrix protein 3.62977
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.0229
TBPL1 TBP-like 1 2.85251
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.36267
TPD52L2 tumor protein D52-like 2 2.36147
BHMT2 betaine--homocysteine S-methyltransferase 2 2.10095
KDM5D lysine (K)-specific demethylase 5D 2.07464

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -5.81842
KIF20A kinesin family member 20A -4.95676
NGRN neugrin, neurite outgrowth associated -4.74711
HSPA8 heat shock 70kDa protein 8 -4.64129
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.09676
SCYL3 SCY1-like 3 (S. cerevisiae) -2.7876
SMC1A structural maintenance of chromosomes 1A -2.69168
KDM5C lysine (K)-specific demethylase 5C -2.15894
MLEC malectin -2.07151