CRCGN016_MCF10A.WT.HP_24H:P08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-toluidine.hcl 33.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 6.34812
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 3.50547
ARID5B AT rich interactive domain 5B (MRF1-like) 3.42546
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.99724
PPARG peroxisome proliferator-activated receptor gamma 2.86316
RPP38 ribonuclease P/MRP 38kDa subunit 2.46437
MARCO macrophage receptor with collagenous structure 2.11236
FRS2 fibroblast growth factor receptor substrate 2 2.09423
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.06542

decreased expression

Symbol Name Standardized Value
TRAPPC3 trafficking protein particle complex 3 -4.72061
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.06839
TLCD3A TLC domain containing 3A -3.80121
CCNB1 cyclin B1 -3.16783
BASP1 brain abundant, membrane attached signal protein 1 -3.1505
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.10518
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.33906
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.32891
MT1X metallothionein 1X -2.30609
FBXO7 F-box protein 7 -2.11521