CRCGN016_MCF10A.WT.HP_24H:P09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-toluidine.hcl 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

24 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 4.92823
ANO10 anoctamin 10 4.01942
ADRB2 adrenoceptor beta 2, surface 3.27687
ACAA1 acetyl-CoA acyltransferase 1 2.71346
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.69369
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.55996
LGMN legumain 2.55764
AXIN1 axin 1 2.35556
IGFBP3 insulin-like growth factor binding protein 3 2.31724
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 2.15142
CGRRF1 cell growth regulator with ring finger domain 1 2.13517
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.10912
CDC73 cell division cycle 73 2.08407
ACAD8 acyl-CoA dehydrogenase family, member 8 2.05278
MORC3 MORC family CW-type zinc finger 3 2.00251

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -4.51721
KRT14 keratin 14, type I -3.93658
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.79112
RBM34 RNA binding motif protein 34 -2.59803
RBM15B RNA binding motif protein 15B -2.3919
TRAP1 TNF receptor-associated protein 1 -2.31788
TNIP1 TNFAIP3 interacting protein 1 -2.20722
TLK2 tousled-like kinase 2 -2.17645
TOMM34 translocase of outer mitochondrial membrane 34 -2.11037