CRCGN016_MCF10A.WT.HP_24H:P13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-nitro-o-anisidine 99.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

42 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 5.51312
BZW2 basic leucine zipper and W2 domains 2 5.17242
UBQLN2 ubiquilin 2 5.09697
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.99071
AGR2 anterior gradient 2 3.90131
BMP4 bone morphogenetic protein 4 3.81382
STK10 serine/threonine kinase 10 3.6658
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.01636
PRR7 proline rich 7 (synaptic) 2.6174
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.56113
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.29339
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.19041
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.0452
DENND2D DENN/MADD domain containing 2D 2.00607
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.00334

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -5.12139
TRAPPC3 trafficking protein particle complex 3 -4.81897
CD44 CD44 molecule (Indian blood group) -4.3109
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.83134
TIMP1 TIMP metallopeptidase inhibitor 1 -3.5089
NUP85 nucleoporin 85kDa -3.33684
KCTD2 potassium channel tetramerization domain containing 2 -3.31897
CANT1 calcium activated nucleotidase 1 -3.22746
TOMM34 translocase of outer mitochondrial membrane 34 -3.13256
SCAND1 SCAN domain containing 1 -3.13151
BASP1 brain abundant, membrane attached signal protein 1 -3.05233
ANXA2 annexin A2 -2.86282
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.54892
FCHSD2 FCH and double SH3 domains 2 -2.49981
FPGS folylpolyglutamate synthase -2.49913
MRPS15 mitochondrial ribosomal protein S15 -2.47198
SLC35F2 solute carrier family 35, member F2 -2.37826
FBXO7 F-box protein 7 -2.29716
MRPS7 mitochondrial ribosomal protein S7 -2.27353
MEAF6 MYST/Esa1-associated factor 6 -2.26542
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.23455
TMEM94 transmembrane protein 94 -2.18933
ACOX1 acyl-CoA oxidase 1, palmitoyl -2.09459
AGO1 argonaute RISC catalytic component 1 -2.08587
FOS FBJ murine osteosarcoma viral oncogene homolog -2.0732
MRPL58 mitochondrial ribosomal protein L58 -2.04801
GRB2 growth factor receptor-bound protein 2 -2.03331