CRCGN016_MCF10A.WT.HP_24H:P15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-nitro-o-anisidine 11.01 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.70205
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.15779
HBA1 hemoglobin, alpha 1 3.84151
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.55814
AGR2 anterior gradient 2 3.37539
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.17221
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 3.16456
LYRM1 LYR motif containing 1 2.97293
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.92052
CDCA4 cell division cycle associated 4 2.80151
COMP cartilage oligomeric matrix protein 2.58688
NUTF2 nuclear transport factor 2 2.41248
KDM5A lysine (K)-specific demethylase 5A 2.31901
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.22293
TBX2 T-box 2 2.13062
TUBA3E tubulin, alpha 3e 2.08534
SATB1 SATB homeobox 1 2.06568
GLOD4 glyoxalase domain containing 4 2.02009

decreased expression

Symbol Name Standardized Value
MRPS2 mitochondrial ribosomal protein S2 -4.37278
COG2 component of oligomeric golgi complex 2 -4.27558
ISOC1 isochorismatase domain containing 1 -3.37618
LAP3 leucine aminopeptidase 3 -3.03398
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.95736
BPHL biphenyl hydrolase-like (serine hydrolase) -2.45183
TMEM115 transmembrane protein 115 -2.41532
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.41277
IFRD2 interferon-related developmental regulator 2 -2.29882
PAEP progestagen-associated endometrial protein -2.20159
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -2.08544
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.08046
SEC16A SEC16 homolog A (S. cerevisiae) -2.03827
CCL4 chemokine (C-C motif) ligand 4 -2.00769