CRCGN016_MCF10A.WT.HP_24H:P17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrososarcosine 32.64 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 4.45421
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.57201
STIMATE STIM activating enhancer 3.16562
TLR4 toll-like receptor 4 3.16433
MDM4 MDM4, p53 regulator 2.73182
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.40448
MAP7 microtubule-associated protein 7 2.36304
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.26116
GIMAP4 GTPase, IMAP family member 4 2.21638
SAR1B secretion associated, Ras related GTPase 1B 2.21429
TBPL1 TBP-like 1 2.08329
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.07426
ANKRD40 ankyrin repeat domain 40 2.00039

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -4.8705
TEX10 testis expressed 10 -3.86187
NPDC1 neural proliferation, differentiation and control, 1 -3.75642
HSPA8 heat shock 70kDa protein 8 -3.47685
TUBB6 tubulin, beta 6 class V -3.43976
RXYLT1 ribitol xylosyltransferase 1 -2.97728
TIMP1 TIMP metallopeptidase inhibitor 1 -2.63243
EIF3D eukaryotic translation initiation factor 3, subunit D -2.42741
GDF15 growth differentiation factor 15 -2.36199
CBR3 carbonyl reductase 3 -2.30358
KDM3A lysine (K)-specific demethylase 3A -2.14969
EIF3L eukaryotic translation initiation factor 3, subunit L -2.00472