CRCGN016_MCF10A.WT.HP_24H:P18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrososarcosine 10.88 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.27722
ACAA1 acetyl-CoA acyltransferase 1 2.9661
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.91315
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.5821
TBPL1 TBP-like 1 2.24228
ZMIZ1 zinc finger, MIZ-type containing 1 2.24204
MELK maternal embryonic leucine zipper kinase 2.2359

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.22171
YME1L1 YME1-like 1 ATPase -4.82624
UBE3C ubiquitin protein ligase E3C -3.53644
MLEC malectin -3.50533
PARD3 par-3 family cell polarity regulator -2.56451
WAC WW domain containing adaptor with coiled-coil -2.46062
COG7 component of oligomeric golgi complex 7 -2.36789
ABI1 abl-interactor 1 -2.23282
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.15571
WDR37 WD repeat domain 37 -2.11229
UNC13D unc-13 homolog D (C. elegans) -2.04168
ZNF629 zinc finger protein 629 -2.0393
PPT2 palmitoyl-protein thioesterase 2 -2.03654
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -2.0256