CRCGN016_MCF10A.WT.HP_24H:P19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-dimethyl s-[2-(methylamino)-2-oxoethyl] dithiophosphate 101.04 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNRIP1 cannabinoid receptor interacting protein 1 4.40834
TBPL1 TBP-like 1 3.38584
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.96764
ZMIZ1 zinc finger, MIZ-type containing 1 2.85714
OLFML2B olfactomedin-like 2B 2.83677
ZNF586 zinc finger protein 586 2.6154
FGFR4 fibroblast growth factor receptor 4 2.60363
ZNF587B zinc finger protein 587B 2.40744
LGMN legumain 2.37729
TPD52L2 tumor protein D52-like 2 2.32597
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.28686
CGRRF1 cell growth regulator with ring finger domain 1 2.24898
PRELID3B PRELI domain containing 3B 2.23187
GATA2 GATA binding protein 2 2.18405
TUBA3E tubulin, alpha 3e 2.07222

decreased expression

Symbol Name Standardized Value
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.21754
MLEC malectin -3.15744
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -3.13205
TAC4 tachykinin 4 (hemokinin) -3.03231
CCDC86 coiled-coil domain containing 86 -2.87545
GDF15 growth differentiation factor 15 -2.86035
CD320 CD320 molecule -2.73702
IFRD2 interferon-related developmental regulator 2 -2.71227
TRAP1 TNF receptor-associated protein 1 -2.60613
STXBP2 syntaxin binding protein 2 -2.47973
HAT1 histone acetyltransferase 1 -2.4306
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.2655
TMEM115 transmembrane protein 115 -2.15795
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.14474
FBXO7 F-box protein 7 -2.139
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.07111