CRCGN017_MCF10A.TP53.M_24H:A04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 5.00258
COMP cartilage oligomeric matrix protein 4.41225
CCDC92 coiled-coil domain containing 92 3.45995
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.25964
MAST2 microtubule associated serine/threonine kinase 2 2.6193
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.36576
DENND2D DENN/MADD domain containing 2D 2.28078
HBB hemoglobin, beta 2.23817
DPH2 DPH2 homolog (S. cerevisiae) 2.23135
TRAPPC4 trafficking protein particle complex 4 2.18486
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.12889
TEX2 testis expressed 2 2.10991
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.09937
CHN1 chimerin 1 2.05612
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.00597

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -5.24539
HMG20B high mobility group 20B -5.00418
COG7 component of oligomeric golgi complex 7 -4.07483
GDF15 growth differentiation factor 15 -3.68913
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.18237
UFM1 ubiquitin-fold modifier 1 -2.48056
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.48023
TEX10 testis expressed 10 -2.41919
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -2.36729
BAX BCL2-associated X protein -2.36663
PIH1D1 PIH1 domain containing 1 -2.18688
SLC35F2 solute carrier family 35, member F2 -2.18222
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.16462
RPP38 ribonuclease P/MRP 38kDa subunit -2.09619