CRCGN017_MCF10A.TP53.M_24H:A08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetohexamide 33.57 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

27 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IGHMBP2 immunoglobulin mu binding protein 2 3.75529
ADGRE5 adhesion G protein-coupled receptor E5 3.68276
FSD1 fibronectin type III and SPRY domain containing 1 3.63716
CXCR4 chemokine (C-X-C motif) receptor 4 3.06999
MELK maternal embryonic leucine zipper kinase 2.63661
WDR7 WD repeat domain 7 2.16056
XPO6 exportin 6 2.13833
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 2.12688
LOC100533997 MAGEA10-MAGEA5 readthrough 2.05585
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.02822

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -3.85566
HAT1 histone acetyltransferase 1 -3.43052
TRAPPC3 trafficking protein particle complex 3 -2.91282
SDC1 syndecan 1 -2.72018
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.64107
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.55694
COL8A2 collagen, type VIII, alpha 2 -2.53718
BPHL biphenyl hydrolase-like (serine hydrolase) -2.5233
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.47305
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.45158
VAT1 vesicle amine transport 1 -2.32419
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.29779
NGRN neugrin, neurite outgrowth associated -2.23922
ATP11B ATPase, class VI, type 11B -2.08635
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.07616
COG7 component of oligomeric golgi complex 7 -2.06945
TDP2 tyrosyl-DNA phosphodiesterase 2 -2.01297