| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,3',4,4'-tetrachloro-1,1'-biphenyl 102.01 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 5.3144 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 5.28359 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.28982 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 3.18038 |
| MAMLD1 | mastermind-like domain containing 1 | 3.02078 |
| KIF5C | kinesin family member 5C | 2.87952 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.83696 |
| BMS1 | BMS1 ribosome biogenesis factor | 2.70615 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 2.56019 |
| DENND2D | DENN/MADD domain containing 2D | 2.47888 |
| NEFM | neurofilament, medium polypeptide | 2.33336 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.26841 |
| RPH3A | rabphilin 3A | 2.25091 |
| PLSCR3 | phospholipid scramblase 3 | 2.24712 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.21493 |
| MTA2 | metastasis associated 1 family, member 2 | 2.20799 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.16325 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 2.16134 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 2.16063 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 2.13906 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | 2.13779 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 2.12929 |
| PARN | poly(A)-specific ribonuclease | 2.12437 |
| TNK1 | tyrosine kinase, non-receptor, 1 | 2.11553 |
| FXYD6-FXYD2 | FXYD6-FXYD2 readthrough | 2.11475 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 2.11441 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.11077 |
| PADI1 | peptidyl arginine deiminase, type I | 2.10937 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 2.10844 |
| C1S | complement component 1, s subcomponent | 2.10577 |
| MMP1 | matrix metallopeptidase 1 | 2.09617 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 | 2.08059 |
| SYT2 | synaptotagmin II | 2.01534 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMG20B | high mobility group 20B | -6.71487 |
| GDF15 | growth differentiation factor 15 | -4.3049 |
| TXNDC9 | thioredoxin domain containing 9 | -4.02032 |
| HSPA8 | heat shock 70kDa protein 8 | -3.99975 |
| IFRD2 | interferon-related developmental regulator 2 | -3.6252 |
| PRPF4 | pre-mRNA processing factor 4 | -3.61614 |
| TMEM115 | transmembrane protein 115 | -3.56566 |
| TUBB6 | tubulin, beta 6 class V | -3.55269 |
| APEH | acylaminoacyl-peptide hydrolase | -3.11136 |
| KRT14 | keratin 14, type I | -3.07472 |
| NCLN | nicalin | -3.02803 |
| MATK | megakaryocyte-associated tyrosine kinase | -3.00584 |
| VDAC1 | voltage-dependent anion channel 1 | -2.83938 |
| GOLT1B | golgi transport 1B | -2.83175 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | -2.78362 |
| TUBA4A | tubulin, alpha 4a | -2.7019 |
| CYB561D2 | cytochrome b561 family, member D2 | -2.62602 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -2.51284 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | -2.50247 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -2.47258 |
| AUP1 | ancient ubiquitous protein 1 | -2.45596 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -2.44213 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -2.41535 |
| ANXA1 | annexin A1 | -2.4085 |
| RNF123 | ring finger protein 123 | -2.38802 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.3622 |
| BMP6 | bone morphogenetic protein 6 | -2.34842 |
| ACY1 | aminoacylase 1 | -2.30401 |
| LMAN2L | lectin, mannose-binding 2-like | -2.29668 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -2.28758 |
| TUSC2 | tumor suppressor candidate 2 | -2.21106 |
| LAMP3 | lysosomal-associated membrane protein 3 | -2.20935 |
| VAC14 | Vac14 homolog (S. cerevisiae) | -2.18462 |
| OXCT1 | 3-oxoacid CoA transferase 1 | -2.17828 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like | -2.17529 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | -2.17402 |
| MLH1 | mutL homolog 1 | -2.09421 |
| TBC1D13 | TBC1 domain family, member 13 | -2.08847 |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit | -2.07455 |
| MFSD12 | major facilitator superfamily domain containing 12 | -2.07056 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | -2.06376 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -2.01457 |
| ATG2A | autophagy related 2A | -2.00612 |
