CRCGN017_MCF10A.TP53.M_24H:A12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3',4,4'-tetrachloro-1,1'-biphenyl 11.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TLR4 toll-like receptor 4 4.70577
RPL39L ribosomal protein L39-like 3.33425
IDE insulin-degrading enzyme 3.28663
NGRN neugrin, neurite outgrowth associated 3.24392
FGFR4 fibroblast growth factor receptor 4 3.05258
ACAA1 acetyl-CoA acyltransferase 1 3.01911
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.90754
SATB1 SATB homeobox 1 2.58179
ACLY ATP citrate lyase 2.28002
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.19635
RSU1 Ras suppressor protein 1 2.12756
AGR2 anterior gradient 2 2.03842
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.00542
CD302 CD302 molecule 2.00309

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.99095
GDF15 growth differentiation factor 15 -4.25686
HMG20B high mobility group 20B -3.53449
ACOT9 acyl-CoA thioesterase 9 -3.38002
APOO apolipoprotein O -2.30414