CRCGN017_MCF10A.TP53.M_24H:A15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pyocyanin 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ALAS1 5'-aminolevulinate synthase 1 3.38988
HDGFL3 HDGF like 3 3.14179
TXNRD1 thioredoxin reductase 1 3.10711
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.52833
HMOX1 heme oxygenase 1 2.36809
LGMN legumain 2.11906
ACAA1 acetyl-CoA acyltransferase 1 2.0701
IGHMBP2 immunoglobulin mu binding protein 2 2.00733

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -3.43451
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.36991
CDC45 cell division cycle 45 -3.06712
PIH1D1 PIH1 domain containing 1 -2.54063
CANT1 calcium activated nucleotidase 1 -2.40185
GOLT1B golgi transport 1B -2.25476
ANXA2 annexin A2 -2.23052