CRCGN017_MCF10A.TP53.M_24H:A16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description galangin 100.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1238 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 10.0
AARS1 alanyl-tRNA synthetase 1 9.60516
NLRP4 NLR family, pyrin domain containing 4 8.71663
GFPT1 glutamine--fructose-6-phosphate transaminase 1 8.54006
IL1B interleukin 1, beta 8.32711
GLRX glutaredoxin (thioltransferase) 8.02133
PYCR1 pyrroline-5-carboxylate reductase 1 7.75
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 7.74529
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 6.68987
NUCB2 nucleobindin 2 6.66997
CCNA1 cyclin A1 6.61939
XPOT exportin, tRNA 6.51622
ATF4 activating transcription factor 4 6.4713
CTSL cathepsin L 6.42809
GARS1 glycyl-tRNA synthetase 1 6.13908
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 6.09798
TRIB3 tribbles pseudokinase 3 5.98026
SLC35B1 solute carrier family 35, member B1 5.8304
LOC128125814 uncharacterized LOC128125814 5.719
PSAT1 phosphoserine aminotransferase 1 5.64996
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 5.59784
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.5392
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.53718
G0S2 G0/G1 switch 2 5.50491
CARS1 cysteinyl-tRNA synthetase 1 5.40997
VSIG2 V-set and immunoglobulin domain containing 2 5.36647
WFS1 Wolfram syndrome 1 (wolframin) 5.35734
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 5.35225
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 5.34007
STXBP1 syntaxin binding protein 1 5.25517
ALAS1 5'-aminolevulinate synthase 1 5.24934
FYN FYN proto-oncogene, Src family tyrosine kinase 5.24892
CDK7 cyclin-dependent kinase 7 5.247
SARS1 seryl-tRNA synthetase 1 5.24401
GRB10 growth factor receptor-bound protein 10 5.23902
SYNGAP1 synaptic Ras GTPase activating protein 1 5.15224
PHGDH phosphoglycerate dehydrogenase 4.98121
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.97427
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 4.95007
HBA1 hemoglobin, alpha 1 4.93568
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.79852
MARS1 methionyl-tRNA synthetase 1 4.7195
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.69255
TES testin LIM domain protein 4.6633
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 4.6093
FHL2 four and a half LIM domains 2 4.58875
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.56209
NCK2 NCK adaptor protein 2 4.54275
HYOU1 hypoxia up-regulated 1 4.49135
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.48989
RAP1GAP RAP1 GTPase activating protein 4.48244
ACTMAP actin maturation protease 4.43605
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 4.43112
TAOK3 TAO kinase 3 4.40431
IFRD1 interferon-related developmental regulator 1 4.40298
RBP4 retinol binding protein 4, plasma 4.37063
GMPPA GDP-mannose pyrophosphorylase A 4.34165
UPP1 uridine phosphorylase 1 4.33835
HDLBP high density lipoprotein binding protein 4.31543
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.30402
TXNRD1 thioredoxin reductase 1 4.26209
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.22835
PLAUR plasminogen activator, urokinase receptor 4.20276
INTS3 integrator complex subunit 3 4.13195
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.12498
TMEM39A transmembrane protein 39A 4.08398
PYGB phosphorylase, glycogen; brain 4.06704
YARS1 tyrosyl-tRNA synthetase 1 4.02891
METTL25B methyltransferase like 25B 4.02574
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 4.01111
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 3.97807
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3.97717
IL1A interleukin 1, alpha 3.97255
WARS1 tryptophanyl-tRNA synthetase 1 3.96746
HBEGF heparin-binding EGF-like growth factor 3.96014
CALU calumenin 3.93536
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.91467
SPAG4 sperm associated antigen 4 3.90702
HMOX1 heme oxygenase 1 3.87281
ZFAND1 zinc finger, AN1-type domain 1 3.8432
EPRS1 glutamyl-prolyl-tRNA synthetase 1 3.83439
ACTC1 actin, alpha, cardiac muscle 1 3.82885
STX1A syntaxin 1A (brain) 3.82253
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.81257
LARP6 La ribonucleoprotein domain family, member 6 3.80501
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 3.78393
LETMD1 LETM1 domain containing 1 3.75523
INPP1 inositol polyphosphate-1-phosphatase 3.74794
CDK5RAP3 CDK5 regulatory subunit associated protein 3 3.7233
RTCA RNA 3'-terminal phosphate cyclase 3.69957
OARD1 O-acyl-ADP-ribose deacylase 1 3.63904
NPIPB5 nuclear pore complex interacting protein family, member B5 3.63814
STC2 stanniocalcin 2 3.6304
AXIN1 axin 1 3.62992
MANF mesencephalic astrocyte-derived neurotrophic factor 3.61758
HSPA13 heat shock protein 70kDa family, member 13 3.59165
MACF1 microtubule-actin crosslinking factor 1 3.57452
AGR2 anterior gradient 2 3.57159
PPARG peroxisome proliferator-activated receptor gamma 3.56511
GTPBP2 GTP binding protein 2 3.56427
IARS1 isoleucyl-tRNA synthetase 1 3.55179
CTNNA2 catenin (cadherin-associated protein), alpha 2 3.54721
CHMP4B charged multivesicular body protein 4B 3.54537
COPB1 coatomer protein complex, subunit beta 1 3.53325
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3.53067
GSTZ1 glutathione S-transferase zeta 1 3.50932
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 3.50837
CCL3L3 chemokine (C-C motif) ligand 3-like 3 3.46306
VLDLR very low density lipoprotein receptor 3.45291
GOLGA3 golgin A3 3.45151
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.4491
FKBP14 FK506 binding protein 14, 22 kDa 3.40723
TTC17 tetratricopeptide repeat domain 17 3.3991
NBAS neuroblastoma amplified sequence 3.37604
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 3.33772
CXCL3 chemokine (C-X-C motif) ligand 3 3.31803
TMEM258 transmembrane protein 258 3.3178
TBPL1 TBP-like 1 3.31053
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 3.29005
USO1 USO1 vesicle transport factor 3.28811
TRIB1 tribbles pseudokinase 1 3.27214
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 3.27166
NFE2L1 nuclear factor, erythroid 2-like 1 3.26834
UFM1 ubiquitin-fold modifier 1 3.2505
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 3.24944
BCL2A1 BCL2-related protein A1 3.24821
CDPF1 cysteine-rich, DPF motif domain containing 1 3.24509
LGMN legumain 3.24241
PGM3 phosphoglucomutase 3 3.24067
MBD5 methyl-CpG binding domain protein 5 3.23933
PDGFA platelet-derived growth factor alpha polypeptide 3.2388
PRAF2 PRA1 domain family, member 2 3.22253
FOSL1 FOS-like antigen 1 3.21295
CLIP1 CAP-GLY domain containing linker protein 1 3.21118
ARCN1 archain 1 3.21033
SERP1 stress-associated endoplasmic reticulum protein 1 3.2006
NFIL3 nuclear factor, interleukin 3 regulated 3.19049
MID1IP1 MID1 interacting protein 1 3.18973
ENTREP1 endosomal transmembrane epsin interactor 1 3.17903
TARS1 threonyl-tRNA synthetase 1 3.17363
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 3.17301
CHI3L2 chitinase 3-like 2 3.16648
FBN2 fibrillin 2 3.16615
CTBS chitobiase, di-N-acetyl- 3.1648
INHBA inhibin, beta A 3.15986
NARS1 asparaginyl-tRNA synthetase 1 3.15896
GATA3 GATA binding protein 3 3.13722
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.13065
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 3.12814
NUP133 nucleoporin 133kDa 3.12676
UFL1 UFM1-specific ligase 1 3.12581
CRAT carnitine O-acetyltransferase 3.11925
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 3.11573
GOLGA8N golgin A8 family, member N 3.09406
SPAG7 sperm associated antigen 7 3.08969
TPM1 tropomyosin 1 (alpha) 3.0891
KCMF1 potassium channel modulatory factor 1 3.0805
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 3.07726
TERF2IP telomeric repeat binding factor 2, interacting protein 3.07652
PLK3 polo-like kinase 3 3.07488
ANO10 anoctamin 10 3.0519
ANKRD11 ankyrin repeat domain 11 3.05123
SEC24D SEC24 family member D 3.04362
CHIC2 cysteine-rich hydrophobic domain 2 3.03612
ACADVL acyl-CoA dehydrogenase, very long chain 3.03206
MLPH melanophilin 3.02182
NPC1 Niemann-Pick disease, type C1 3.00093
HAX1 HCLS1 associated protein X-1 3.00085
CAMTA2 calmodulin binding transcription activator 2 2.98922
CDC25B cell division cycle 25B 2.98498
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.97996
PGR progesterone receptor 2.97859
KCTD5 potassium channel tetramerization domain containing 5 2.97755
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.97523
EFHD1 EF-hand domain family, member D1 2.96629
SLC67A1 solute carrier family 67 member 1 2.96282
SLC75A1 solute carrier family 75 member 1 2.9593
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.95812
EMX2 empty spiracles homeobox 2 2.95778
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.95025
SIL1 SIL1 nucleotide exchange factor 2.93958
MANBA mannosidase, beta A, lysosomal 2.93408
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.9249
NDEL1 nudE neurodevelopment protein 1-like 1 2.91218
KLHDC2 kelch domain containing 2 2.91075
COPZ2 coatomer protein complex, subunit zeta 2 2.90949
PARP6 poly (ADP-ribose) polymerase family, member 6 2.89274
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 2.89153
GCC1 GRIP and coiled-coil domain containing 1 2.89086
FLNB filamin B, beta 2.88597
OLAH oleoyl-ACP hydrolase 2.88295
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.87042
NGLY1 N-glycanase 1 2.86554
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.8626
MTIF2 mitochondrial translational initiation factor 2 2.85392
OMG oligodendrocyte myelin glycoprotein 2.8493
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.84929
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.84813
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.84793
CXCL5 chemokine (C-X-C motif) ligand 5 2.84541
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 2.83493
EIF4A2 eukaryotic translation initiation factor 4A2 2.83284
GRM3 glutamate receptor, metabotropic 3 2.83265
KRT6B keratin 6B, type II 2.82849
USP3 ubiquitin specific peptidase 3 2.82263
S100A12 S100 calcium binding protein A12 2.8196
ATXN3 ataxin 3 2.81897
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.81758
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.81597
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 2.81473
SH3GL3 SH3-domain GRB2-like 3 2.8125
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.812
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.8077
SUCO SUN domain containing ossification factor 2.79726
SEC63 SEC63 homolog (S. cerevisiae) 2.79549
GADD45A growth arrest and DNA-damage-inducible, alpha 2.79142
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.78686
CYB5R2 cytochrome b5 reductase 2 2.78655
MTFR1 mitochondrial fission regulator 1 2.78491
TFF1 trefoil factor 1 2.78424
WIF1 WNT inhibitory factor 1 2.78263
KIZ kizuna centrosomal protein 2.78069
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.77985
PFDN2 prefoldin subunit 2 2.77591
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.77563
OFD1 oral-facial-digital syndrome 1 2.77391
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.76948
AKTIP AKT interacting protein 2.7668
CREB5 cAMP responsive element binding protein 5 2.76024
GID4 GID complex subunit 4 2.75328
STX8 syntaxin 8 2.75193
KDM7A lysine (K)-specific demethylase 7A 2.74969
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.74446
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.74237
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.74053
ANO1 anoctamin 1, calcium activated chloride channel 2.73596
AGTPBP1 ATP/GTP binding protein 1 2.72963
CCDC90B coiled-coil domain containing 90B 2.7216
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.71053
CRELD1 cysteine-rich with EGF-like domains 1 2.70816
CCPG1 cell cycle progression 1 2.70752
MAP1B microtubule-associated protein 1B 2.70627
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.70408
MAN2A1 mannosidase, alpha, class 2A, member 1 2.69701
FZD10 frizzled class receptor 10 2.69314
FKBP11 FK506 binding protein 11, 19 kDa 2.6925
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.68908
TNIP2 TNFAIP3 interacting protein 2 2.68691
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 2.68473
RMC1 regulator of MON1-CCZ1 2.67209
ETNPPL ethanolamine-phosphate phospho-lyase 2.67011
CSP2 CS pseudogene 2 2.66782
NUPR1 nuclear protein, transcriptional regulator, 1 2.66528
LOC102724560 cystathionine beta-synthase 2.66429
ELF5 E74-like factor 5 (ets domain transcription factor) 2.66417
IRS1 insulin receptor substrate 1 2.65996
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.65396
ETHE1 ethylmalonic encephalopathy 1 2.65095
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.64776
SYT1 synaptotagmin I 2.64414
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.63828
SEC23B Sec23 homolog B (S. cerevisiae) 2.63584
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.62366
COG5 component of oligomeric golgi complex 5 2.62246
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2.61822
CREB3L2 cAMP responsive element binding protein 3-like 2 2.6143
ZBTB10 zinc finger and BTB domain containing 10 2.61389
RIPK2 receptor-interacting serine-threonine kinase 2 2.60521
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.60406
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.58799
COL5A3 collagen, type V, alpha 3 2.58226
ZNF365 zinc finger protein 365 2.5768
HDAC4 histone deacetylase 4 2.57559
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.57523
LYRM1 LYR motif containing 1 2.57406
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.57212
ANKRD37 ankyrin repeat domain 37 2.57199
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 2.5719
NOP53 NOP53 ribosome biogenesis factor 2.55592
EIF1 eukaryotic translation initiation factor 1 2.55203
ECH1 enoyl CoA hydratase 1, peroxisomal 2.54998
SEC61G Sec61 gamma subunit 2.54701
AKAP17A A kinase (PRKA) anchor protein 17A 2.53439
GCC2 GRIP and coiled-coil domain containing 2 2.52983
TUFT1 tuftelin 1 2.5279
FGF9 fibroblast growth factor 9 2.52147
ZPR1 ZPR1 zinc finger 2.51881
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.51193
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.50652
RASL11B RAS-like, family 11, member B 2.50394
TMED5 transmembrane emp24 protein transport domain containing 5 2.50284
ERLIN2 ER lipid raft associated 2 2.50273
DVL1 dishevelled segment polarity protein 1 2.49902
DOCK6 dedicator of cytokinesis 6 2.49769
RBKS ribokinase 2.49689
TRAF3IP2 TRAF3 interacting protein 2 2.49509
PSD3 pleckstrin and Sec7 domain containing 3 2.49362
PDZRN3 PDZ domain containing ring finger 3 2.49263
APLNR apelin receptor 2.49237
MYDGF myeloid-derived growth factor 2.49221
CEP290 centrosomal protein 290kDa 2.49084
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.49028
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.48571
CD63 CD63 molecule 2.48412
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2.47669
NDRG1 N-myc downstream regulated 1 2.47624
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.47578
NAMPT nicotinamide phosphoribosyltransferase 2.47021
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.4676
ATP9A ATPase, class II, type 9A 2.46472
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.46387
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.46317
LIN7A lin-7 homolog A (C. elegans) 2.4628
ODR4 odr-4 GPCR localization factor homolog 2.46266
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.45866
ITCH itchy E3 ubiquitin protein ligase 2.45832
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 2.44656
HBB hemoglobin, beta 2.44614
LOC122539214 Zinc finger protein LOC122539214 2.44383
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.44023
AQP9 aquaporin 9 2.44012
MYH9 myosin, heavy chain 9, non-muscle 2.43992
PLIN2 perilipin 2 2.43554
GRAMD2B GRAM domain containing 2B 2.43475
SLC44A1 solute carrier family 44 (choline transporter), member 1 2.43107
ZNF518A zinc finger protein 518A 2.42683
ZNF385D zinc finger protein 385D 2.42636
TFF3 trefoil factor 3 (intestinal) 2.42625
SPG11 spastic paraplegia 11 (autosomal recessive) 2.42612
ITGAV integrin, alpha V 2.42484
STUM stum, mechanosensory transduction mediator homolog 2.41625
PGAP6 post-GPI attachment to proteins 6 2.41408
NSUN5 NOP2/Sun domain family, member 5 2.41266
ARMCX3 armadillo repeat containing, X-linked 3 2.41217
P4HB prolyl 4-hydroxylase, beta polypeptide 2.41103
JMJD1C jumonji domain containing 1C 2.40268
TMEM40 transmembrane protein 40 2.39644
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 2.39427
PLCD1 phospholipase C, delta 1 2.39345
TRIP12 thyroid hormone receptor interactor 12 2.39146
HEMK1 HemK methyltransferase family member 1 2.39016
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.38878
NT5E 5'-nucleotidase, ecto (CD73) 2.38682
STBD1 starch binding domain 1 2.38466
ACVR1 activin A receptor, type I 2.38288
NMRK1 nicotinamide riboside kinase 1 2.37112
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.36616
RNF170 ring finger protein 170 2.36358
SIAH2 siah E3 ubiquitin protein ligase 2 2.36323
MOSPD2 motile sperm domain containing 2 2.3618
P3H1 prolyl 3-hydroxylase 1 2.35975
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.35913
ULBP2 UL16 binding protein 2 2.35645
MATN3 matrilin 3 2.35585
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.35457
LCMT1 leucine carboxyl methyltransferase 1 2.35239
STX5 syntaxin 5 2.34891
SNX6 sorting nexin 6 2.34847
ZNF862 zinc finger protein 862 2.33812
MYO6 myosin VI 2.33647
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough 2.33328
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.33232
TSPAN7 tetraspanin 7 2.32657
IST1 increased sodium tolerance 1 homolog (yeast) 2.32431
MPST mercaptopyruvate sulfurtransferase 2.32196
IL36RN interleukin 36 receptor antagonist 2.32135
STK38L serine/threonine kinase 38 like 2.32122
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.32035
RPN1 ribophorin I 2.31898
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.31819
GYPC glycophorin C (Gerbich blood group) 2.31655
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.31638
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.31552
VEGFA vascular endothelial growth factor A 2.31447
KCTD13 potassium channel tetramerization domain containing 13 2.31265
RGPD8 RANBP2-like and GRIP domain containing 8 2.30988
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.30792
H1-0 H1.0 linker histone 2.30384
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.30382
MZT2B mitotic spindle organizing protein 2B 2.29767
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.29512
PLEK pleckstrin 2.29467
MAN2C1 mannosidase, alpha, class 2C, member 1 2.29305
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.29244
SH3YL1 SH3 and SYLF domain containing 1 2.29033
CDKL3 cyclin-dependent kinase-like 3 2.28989
SEC16A SEC16 homolog A (S. cerevisiae) 2.28736
CXCL2 chemokine (C-X-C motif) ligand 2 2.28587
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.28576
TREM1 triggering receptor expressed on myeloid cells 1 2.28539
AMZ2 archaelysin family metallopeptidase 2 2.28319
LONP2 lon peptidase 2, peroxisomal 2.28213
CLDN4 claudin 4 2.28192
RANBP9 RAN binding protein 9 2.281
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.28065
EGR3 early growth response 3 2.2801
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.27858
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.27479
RIOK3 RIO kinase 3 2.27426
THBS3 thrombospondin 3 2.27263
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 2.26898
CCL4 chemokine (C-C motif) ligand 4 2.26473
SCFD1 sec1 family domain containing 1 2.25966
GABARAPL1 GABA(A) receptor-associated protein like 1 2.25895
RPS25 ribosomal protein S25 2.25478
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.25445
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 2.25434
NPIPB4 nuclear pore complex interacting protein family, member B4 2.25338
PRSS3 protease, serine, 3 2.25273
ACAA1 acetyl-CoA acyltransferase 1 2.25215
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.25132
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.24983
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 2.2497
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.24673
KRT16 keratin 16, type I 2.246
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.24521
DIXDC1 DIX domain containing 1 2.24469
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.24107
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.24082
STYXL1 serine/threonine/tyrosine interacting-like 1 2.23964
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2.23957
GAB2 GRB2-associated binding protein 2 2.23931
GATAD1 GATA zinc finger domain containing 1 2.23686
DNAH7 dynein, axonemal, heavy chain 7 2.23595
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.23072
RMDN1 regulator of microtubule dynamics 1 2.22835
SQSTM1 sequestosome 1 2.22654
LOC127933115 uncharacterized LOC127933115 2.22576
IGFBP1 insulin-like growth factor binding protein 1 2.22517
NT5M 5',3'-nucleotidase, mitochondrial 2.22341
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.22286
PAQR6 progestin and adipoQ receptor family member VI 2.22216
MAGEL2 melanoma antigen family L2 2.22102
TTC28 tetratricopeptide repeat domain 28 2.22043
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.2183
PHYH phytanoyl-CoA 2-hydroxylase 2.21769
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.21586
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.21172
TNNC1 troponin C type 1 (slow) 2.21079
STC1 stanniocalcin 1 2.2075
MAP4 microtubule-associated protein 4 2.20349
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.19944
ABHD4 abhydrolase domain containing 4 2.19815
TECPR2 tectonin beta-propeller repeat containing 2 2.19325
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 2.19223
CD53 CD53 molecule 2.19137
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.19117
RWDD2A RWD domain containing 2A 2.19012
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.18706
ROPN1B rhophilin associated tail protein 1B 2.18152
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.18081
MZT2A mitotic spindle organizing protein 2A 2.18025
R3HDM2 R3H domain containing 2 2.17858
CALCOCO2 calcium binding and coiled-coil domain 2 2.17846
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 2.17609
POT1 protection of telomeres 1 2.17456
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.17413
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.16773
PDIA4 protein disulfide isomerase family A, member 4 2.1675
OXTR oxytocin receptor 2.16747
MYO5A myosin VA (heavy chain 12, myoxin) 2.16358
PROM1 prominin 1 2.16327
MYBPC1 myosin binding protein C, slow type 2.16261
SULF1 sulfatase 1 2.16233
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 2.16078
MSRA methionine sulfoxide reductase A 2.1586
TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase 2.15656
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.15631
NPAS2 neuronal PAS domain protein 2 2.15471
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.15431
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 2.15291
CSNK1E casein kinase 1, epsilon 2.1529
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.1522
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.15213
MPPED2 metallophosphoesterase domain containing 2 2.14646
DPH5 diphthamide biosynthesis 5 2.14546
LRRC2 leucine rich repeat containing 2 2.14534
TSGA10 testis specific, 10 2.14527
PXDC1 PX domain containing 1 2.14517
TPD52L1 tumor protein D52-like 1 2.14431
EIF3H eukaryotic translation initiation factor 3, subunit H 2.14205
CIRSR corepressor of RBPJ and splicing regulator 2.14134
TP53BP2 tumor protein p53 binding protein 2 2.14132
ZNF23 zinc finger protein 23 2.14095
PADI2 peptidyl arginine deiminase, type II 2.13932
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.13847
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.13828
ESRP1 epithelial splicing regulatory protein 1 2.13544
CD44 CD44 molecule (Indian blood group) 2.13312
DAAM1 dishevelled associated activator of morphogenesis 1 2.13248
CDX1 caudal type homeobox 1 2.13247
BET1L Bet1 golgi vesicular membrane trafficking protein-like 2.13247
MSH5 mutS homolog 5 2.1315
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.12224
CEP57 centrosomal protein 57kDa 2.12171
SCRG1 stimulator of chondrogenesis 1 2.12157
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2.12115
LOC114841035 uncharacterized LOC114841035 2.12074
PTPRM protein tyrosine phosphatase, receptor type, M 2.1207
LONP1 lon peptidase 1, mitochondrial 2.12062
IL36G interleukin 36, gamma 2.12034
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.11991
SSR4 signal sequence receptor, delta 2.11793
SNAI1 snail family zinc finger 1 2.11685
CFHR5 complement factor H-related 5 2.11543
TALDO1 transaldolase 1 2.11347
RNF103 ring finger protein 103 2.11342
COL6A3 collagen, type VI, alpha 3 2.11265
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.11114
IER3 immediate early response 3 2.10839
PRSS2 protease, serine, 2 (trypsin 2) 2.10724
CAPRIN2 caprin family member 2 2.10717
ITGA6 integrin, alpha 6 2.1061
IFT88 intraflagellar transport 88 2.10565
BMP6 bone morphogenetic protein 6 2.1056
CLDND1 claudin domain containing 1 2.10472
LAMB3 laminin, beta 3 2.10441
ZDHHC14 zinc finger, DHHC-type containing 14 2.10057
POLI polymerase (DNA directed) iota 2.09939
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.0963
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.09495
KDM6B lysine (K)-specific demethylase 6B 2.0947
MOBP myelin-associated oligodendrocyte basic protein 2.09414
PALLD palladin, cytoskeletal associated protein 2.09408
CDCP1 CUB domain containing protein 1 2.09324
ZNF516 zinc finger protein 516 2.09192
BRD7 bromodomain containing 7 2.08609
CSRNP2 cysteine-serine-rich nuclear protein 2 2.08431
GRB14 growth factor receptor-bound protein 14 2.08254
RUSC2 RUN and SH3 domain containing 2 2.08166
MON1B MON1 secretory trafficking family member B 2.08103
BABAM2 BRISC and BRCA1 A complex member 2 2.08027
SOX10 SRY (sex determining region Y)-box 10 2.07933
TGIF1 TGFB-induced factor homeobox 1 2.07918
PAPPA2 pappalysin 2 2.07875
DUSP5 dual specificity phosphatase 5 2.07864
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 2.07848
DLX5 distal-less homeobox 5 2.07816
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.07801
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.07616
WDR19 WD repeat domain 19 2.07583
INHBE inhibin, beta E 2.07322
FAM114A1 family with sequence similarity 114, member A1 2.07023
RGS10 regulator of G-protein signaling 10 2.06882
AKAP9 A kinase (PRKA) anchor protein 9 2.06836
ARHGAP32 Rho GTPase activating protein 32 2.06739
FICD FIC domain containing 2.06635
TBL1X transducin (beta)-like 1X-linked 2.06579
EREG epiregulin 2.06406
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.06253
ATXN1 ataxin 1 2.06242
IFI6 interferon, alpha-inducible protein 6 2.06242
MRPS33 mitochondrial ribosomal protein S33 2.06172
MFGE8 milk fat globule-EGF factor 8 protein 2.06149
SYT17 synaptotagmin XVII 2.05987
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.05712
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 2.05696
LOC124904395 uncharacterized LOC124904395 2.05519
ERCC1 excision repair cross-complementation group 1 2.05307
CNN1 calponin 1, basic, smooth muscle 2.04976
TTLL1 tubulin tyrosine ligase-like family member 1 2.04749
PTPRE protein tyrosine phosphatase, receptor type, E 2.04747
SMTN smoothelin 2.04682
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.04592
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.04437
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.04325
GOLGA4 golgin A4 2.04073
PABPC3 poly(A) binding protein, cytoplasmic 3 2.03984
BAMBI BMP and activin membrane-bound inhibitor 2.0391
KIF21B kinesin family member 21B 2.03735
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.03616
MACROD1 MACRO domain containing 1 2.03485
MYO18A myosin XVIIIA 2.03468
UBXN4 UBX domain protein 4 2.03452
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.03412
SRP54 signal recognition particle 54kDa 2.03319
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.03271
CST1 cystatin SN 2.03202
S100P S100 calcium binding protein P 2.02995
ERBIN erbb2 interacting protein 2.02968
STX4 syntaxin 4 2.02953
NOD2 nucleotide-binding oligomerization domain containing 2 2.02877
FERMT2 fermitin family member 2 2.02843
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.02734
PDLIM5 PDZ and LIM domain 5 2.02666
TEX14 testis expressed 14 2.02614
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.02446
SMPX small muscle protein, X-linked 2.02361
TSKU tsukushi, small leucine rich proteoglycan 2.02227
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.02216
HOMER1 homer scaffolding protein 1 2.02171
CTAGE8 CTAGE family, member 8 2.01958
AZU1 azurocidin 1 2.01863
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.01667
COL5A2 collagen, type V, alpha 2 2.01617
BCL10 B-cell CLL/lymphoma 10 2.01447
MKRN1 makorin ring finger protein 1 2.01321
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.01274
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 2.01251
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.01177
IRF6 interferon regulatory factor 6 2.01132
MNDA myeloid cell nuclear differentiation antigen 2.01048
ZNF426 zinc finger protein 426 2.00906
BSN bassoon presynaptic cytomatrix protein 2.00643
AHCYL1 adenosylhomocysteinase-like 1 2.00555
LRP10 low density lipoprotein receptor-related protein 10 2.00209

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -9.20064
TMEM50A transmembrane protein 50A -7.3023
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -7.26227
MCM3 minichromosome maintenance complex component 3 -7.09485
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.3422
HOXA5 homeobox A5 -6.31597
S100A4 S100 calcium binding protein A4 -6.09436
ELOVL6 ELOVL fatty acid elongase 6 -6.04073
KIF20A kinesin family member 20A -5.90828
INSIG1 insulin induced gene 1 -5.83435
NSDHL NAD(P) dependent steroid dehydrogenase-like -5.77963
SH3D19 SH3 domain containing 19 -5.7164
CDC45 cell division cycle 45 -5.66279
NUSAP1 nucleolar and spindle associated protein 1 -5.60506
ADI1 acireductone dioxygenase 1 -5.60207
PCNA proliferating cell nuclear antigen -5.57448
DHCR24 24-dehydrocholesterol reductase -5.40819
DCK deoxycytidine kinase -5.25074
TUBB6 tubulin, beta 6 class V -5.13858
MSH2 mutS homolog 2 -5.11604
MCM5 minichromosome maintenance complex component 5 -5.07827
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -5.0276
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.99762
PARP1 poly (ADP-ribose) polymerase 1 -4.834
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.8157
GTPBP8 GTP-binding protein 8 (putative) -4.79986
FEN1 flap structure-specific endonuclease 1 -4.77337
MCM6 minichromosome maintenance complex component 6 -4.7397
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.73876
BID BH3 interacting domain death agonist -4.7099
AURKB aurora kinase B -4.68179
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.65794
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.60292
SHMT1 serine hydroxymethyltransferase 1 (soluble) -4.59294
CENPM centromere protein M -4.55713
SOAT2 sterol O-acyltransferase 2 -4.50842
OIP5 Opa interacting protein 5 -4.42316
BIRC5 baculoviral IAP repeat containing 5 -4.4159
TK1 thymidine kinase 1, soluble -4.36312
NUP85 nucleoporin 85kDa -4.33721
STMN1 stathmin 1 -4.33359
ERCC6L excision repair cross-complementation group 6-like -4.33082
SRSF2 serine/arginine-rich splicing factor 2 -4.30649
ASF1B anti-silencing function 1B histone chaperone -4.28998
SPC25 SPC25, NDC80 kinetochore complex component -4.28766
GMNN geminin, DNA replication inhibitor -4.28217
CCND3 cyclin D3 -4.25382
PRCP prolylcarboxypeptidase (angiotensinase C) -4.20779
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -4.16021
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -4.1499
GINS3 GINS complex subunit 3 (Psf3 homolog) -4.12678
PUF60 poly-U binding splicing factor 60KDa -4.1084
CRYZ crystallin, zeta (quinone reductase) -4.10395
FKBP5 FK506 binding protein 5 -4.08856
CD320 CD320 molecule -4.07176
MCMBP minichromosome maintenance complex binding protein -4.05149
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -4.03436
RFC2 replication factor C (activator 1) 2, 40kDa -4.01826
MVD mevalonate (diphospho) decarboxylase -4.0054
PGRMC1 progesterone receptor membrane component 1 -3.99703
WDR76 WD repeat domain 76 -3.98649
CCNF cyclin F -3.94876
IDI1 isopentenyl-diphosphate delta isomerase 1 -3.94339
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -3.93027
MAT2A methionine adenosyltransferase II, alpha -3.90318
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.90021
SQLE squalene epoxidase -3.88199
HEXIM1 hexamethylene bis-acetamide inducible 1 -3.86008
FASTKD3 FAST kinase domains 3 -3.85277
ALDOC aldolase C, fructose-bisphosphate -3.83458
KIF11 kinesin family member 11 -3.83422
BRCA1 breast cancer 1, early onset -3.77564
MCM7 minichromosome maintenance complex component 7 -3.76991
SRSF3 serine/arginine-rich splicing factor 3 -3.74082
CDK4 cyclin-dependent kinase 4 -3.73942
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -3.72432
CDC25C cell division cycle 25C -3.71363
LCMT2 leucine carboxyl methyltransferase 2 -3.69327
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.69282
HOXA4 homeobox A4 -3.68809
MRPL12 mitochondrial ribosomal protein L12 -3.68673
HAT1 histone acetyltransferase 1 -3.67807
CDCA3 cell division cycle associated 3 -3.67515
NAP1L4 nucleosome assembly protein 1-like 4 -3.64888
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -3.6298
CPNE3 copine III -3.61969
RUSC1 RUN and SH3 domain containing 1 -3.60863
RPA3 replication protein A3, 14kDa -3.60761
DHCR7 7-dehydrocholesterol reductase -3.59279
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.58942
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.57717
EXO1 exonuclease 1 -3.57402
SLC25A46 solute carrier family 25, member 46 -3.57003
HELLS helicase, lymphoid-specific -3.54842
SCD stearoyl-CoA desaturase (delta-9-desaturase) -3.52569
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.52466
MCM10 minichromosome maintenance complex component 10 -3.52269
RRM1 ribonucleotide reductase M1 -3.51407
RAD51AP1 RAD51 associated protein 1 -3.50857
GET3 guided entry of tail-anchored proteins factor 3, ATPase -3.48176
MOCS3 molybdenum cofactor synthesis 3 -3.47476
PRPF31 pre-mRNA processing factor 31 -3.47282
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -3.4645
JPT2 Jupiter microtubule associated homolog 2 -3.4538
OAT ornithine aminotransferase -3.45295
DHFR dihydrofolate reductase -3.45206
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -3.4495
MCM4 minichromosome maintenance complex component 4 -3.42413
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -3.41377
MRPS7 mitochondrial ribosomal protein S7 -3.41049
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.40023
NYNRIN NYN domain and retroviral integrase containing -3.39731
TTC27 tetratricopeptide repeat domain 27 -3.39516
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -3.39497
SREBF1 sterol regulatory element binding transcription factor 1 -3.39294
SREBF2 sterol regulatory element binding transcription factor 2 -3.37778
TMPO thymopoietin -3.35809
TMEM14A transmembrane protein 14A -3.34901
CBR1 carbonyl reductase 1 -3.34553
ATAD2 ATPase family, AAA domain containing 2 -3.3341
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -3.32688
GPD1L glycerol-3-phosphate dehydrogenase 1-like -3.32312
C1QBP complement component 1, q subcomponent binding protein -3.30716
SESN1 sestrin 1 -3.30602
CDC6 cell division cycle 6 -3.30539
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -3.29936
LMBR1 limb development membrane protein 1 -3.29451
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -3.29154
NUP160 nucleoporin 160kDa -3.29071
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -3.28149
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -3.26955
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.26864
ABT1 activator of basal transcription 1 -3.26813
MDH1 malate dehydrogenase 1, NAD (soluble) -3.26181
TRIP13 thyroid hormone receptor interactor 13 -3.25559
NT5DC2 5'-nucleotidase domain containing 2 -3.25037
CYCS cytochrome c, somatic -3.24829
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -3.24481
TXNDC9 thioredoxin domain containing 9 -3.24176
DCTPP1 dCTP pyrophosphatase 1 -3.23901
FLOT2 flotillin 2 -3.22684
PCLAF PCNA clamp associated factor -3.21933
CDC7 cell division cycle 7 -3.2033
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.20277
HARS1 histidyl-tRNA synthetase 1 -3.19439
EBNA1BP2 EBNA1 binding protein 2 -3.18776
BPIFA1 BPI fold containing family A, member 1 -3.17939
EXOSC9 exosome component 9 -3.16259
ZNF180 zinc finger protein 180 -3.15758
JADE2 jade family PHD finger 2 -3.15496
MAT2B methionine adenosyltransferase II, beta -3.14923
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -3.14122
PARPBP PARP1 binding protein -3.14095
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.13615
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -3.13229
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.13161
NCAPD2 non-SMC condensin I complex, subunit D2 -3.12852
MVK mevalonate kinase -3.12678
PGC progastricsin (pepsinogen C) -3.1263
AKT1 v-akt murine thymoma viral oncogene homolog 1 -3.12524
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -3.12488
CDC25A cell division cycle 25A -3.12229
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -3.11908
NELFCD negative elongation factor complex member C/D -3.11629
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.10379
RUVBL1 RuvB-like AAA ATPase 1 -3.10096
ZC3H4 zinc finger CCCH-type containing 4 -3.08589
NASP nuclear autoantigenic sperm protein (histone-binding) -3.07134
RRM2 ribonucleotide reductase M2 -3.06974
ZNF207 zinc finger protein 207 -3.06783
MRM2 mitochondrial rRNA methyltransferase 2 -3.06478
TSPAN3 tetraspanin 3 -3.06455
SOCS5 suppressor of cytokine signaling 5 -3.05669
CCNB1 cyclin B1 -3.05615
TMX1 thioredoxin-related transmembrane protein 1 -3.05085
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -3.04783
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -3.04607
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.0431
ZBTB24 zinc finger and BTB domain containing 24 -3.03692
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.03636
STX10 syntaxin 10 -3.02571
ABHD14A abhydrolase domain containing 14A -3.02505
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -3.02187
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.0144
KIF18B kinesin family member 18B -3.00815
ACLY ATP citrate lyase -3.0077
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.0006
SLC61A1 solute carrier family 61 member 1 -3.00024
DSN1 DSN1, MIS12 kinetochore complex component -2.99933
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.99733
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.99436
BEX3 brain expressed X-linked 3 -2.98888
PYDC1 PYD (pyrin domain) containing 1 -2.98754
CCNB2 cyclin B2 -2.98597
FN3KRP fructosamine 3 kinase related protein -2.98281
TMEM177 transmembrane protein 177 -2.97854
CENPI centromere protein I -2.9688
CENPU centromere protein U -2.9673
SPAG5 sperm associated antigen 5 -2.95831
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.9556
SPPL2A signal peptide peptidase like 2A -2.95474
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -2.9519
NUBP2 nucleotide binding protein 2 -2.94887
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.94709
FANCC Fanconi anemia, complementation group C -2.94356
PRR15L proline rich 15-like -2.94322
PAQR4 progestin and adipoQ receptor family member IV -2.93971
UBE2M ubiquitin-conjugating enzyme E2M -2.93884
FARSA phenylalanyl-tRNA synthetase, alpha subunit -2.92783
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.92771
FOXM1 forkhead box M1 -2.9271
RNASE7 ribonuclease, RNase A family, 7 -2.92044
ANKRD10 ankyrin repeat domain 10 -2.91481
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.91355
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.9062
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -2.90533
NDC80 NDC80 kinetochore complex component -2.90243
QRICH1 glutamine-rich 1 -2.89952
NUP62 nucleoporin 62kDa -2.89525
RFC3 replication factor C (activator 1) 3, 38kDa -2.89339
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.88343
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.88198
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.88095
MYO19 myosin XIX -2.87999
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.87841
MRS2 MRS2 magnesium transporter -2.8739
GPS1 G protein pathway suppressor 1 -2.87297
GRWD1 glutamate-rich WD repeat containing 1 -2.86769
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.8538
TUBGCP4 tubulin, gamma complex associated protein 4 -2.83981
FBXO9 F-box protein 9 -2.83593
PNPLA3 patatin-like phospholipase domain containing 3 -2.83421
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -2.83303
WDR77 WD repeat domain 77 -2.83271
BZW2 basic leucine zipper and W2 domains 2 -2.83124
SCARB1 scavenger receptor class B, member 1 -2.83013
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.82211
FGFR3 fibroblast growth factor receptor 3 -2.81605
CISD1 CDGSH iron sulfur domain 1 -2.81207
SMC4 structural maintenance of chromosomes 4 -2.80407
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.79978
PDHB pyruvate dehydrogenase (lipoamide) beta -2.79606
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.79241
RTL10 retrotransposon Gag like 10 -2.79123
TUBA1B tubulin, alpha 1b -2.79015
ZNF274 zinc finger protein 274 -2.78882
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.78864
SNRPC small nuclear ribonucleoprotein polypeptide C -2.78813
ATRIP ATR interacting protein -2.78444
FAM32A family with sequence similarity 32, member A -2.78009
AMDHD2 amidohydrolase domain containing 2 -2.76786
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.76276
CA9 carbonic anhydrase IX -2.76105
IPO9 importin 9 -2.76033
HPS6 Hermansky-Pudlak syndrome 6 -2.75298
PXMP4 peroxisomal membrane protein 4, 24kDa -2.74774
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.73931
HSPB1 heat shock 27kDa protein 1 -2.7353
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.7208
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.71618
DNA2 DNA replication helicase/nuclease 2 -2.7161
TBC1D10C TBC1 domain family, member 10C -2.71402
CENPX centromere protein X -2.71063
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.71055
MICA MHC class I polypeptide-related sequence A -2.7048
RFX5 regulatory factor X, 5 (influences HLA class II expression) -2.70256
ZNF35 zinc finger protein 35 -2.70079
NCAPH non-SMC condensin I complex, subunit H -2.69107
FUS FUS RNA binding protein -2.68771
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.6868
FAM13B family with sequence similarity 13, member B -2.6857
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.68363
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.68291
HSBP1 heat shock factor binding protein 1 -2.68269
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.67982
LAGE3 L antigen family, member 3 -2.67915
CCDC47 coiled-coil domain containing 47 -2.67813
MSH6 mutS homolog 6 -2.67457
RABIF RAB interacting factor -2.67054
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.66337
NOL11 nucleolar protein 11 -2.66209
CLEC16A C-type lectin domain family 16, member A -2.66081
CCNE2 cyclin E2 -2.6605
SRSF1 serine/arginine-rich splicing factor 1 -2.65894
MVP major vault protein -2.6521
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.64585
GDF2 growth differentiation factor 2 -2.64419
KIF18A kinesin family member 18A -2.64412
ZNF629 zinc finger protein 629 -2.63736
LMNB1 lamin B1 -2.63614
TATDN2 TatD DNase domain containing 2 -2.63356
ASTE1 asteroid homolog 1 (Drosophila) -2.63048
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.6292
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.62317
GEMIN4 gem (nuclear organelle) associated protein 4 -2.62007
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.61972
CENPA centromere protein A -2.61891
TMEM9B TMEM9 domain family, member B -2.61769
THUMPD2 THUMP domain containing 2 -2.61639
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -2.61597
CCNA2 cyclin A2 -2.61539
CDCA4 cell division cycle associated 4 -2.61415
HMGB1 high mobility group box 1 -2.61264
RANBP1 RAN binding protein 1 -2.61106
ZNF512B zinc finger protein 512B -2.60817
TUSC2 tumor suppressor candidate 2 -2.60611
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.60488
TEDC2 tubulin epsilon and delta complex 2 -2.60367
SAE1 SUMO1 activating enzyme subunit 1 -2.60117
SLC25A44 solute carrier family 25, member 44 -2.59812
UMPS uridine monophosphate synthetase -2.59285
EAPP E2F-associated phosphoprotein -2.59018
PIMREG PICALM interacting mitotic regulator -2.57888
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.57771
CDKN2AIP CDKN2A interacting protein -2.57398
CCDC51 coiled-coil domain containing 51 -2.57195
ATP5MF ATP synthase membrane subunit f -2.56852
EMP2 epithelial membrane protein 2 -2.56553
TFAM transcription factor A, mitochondrial -2.56444
EIF4A3 eukaryotic translation initiation factor 4A3 -2.56343
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.55617
KIF23 kinesin family member 23 -2.55086
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.5452
E2F8 E2F transcription factor 8 -2.54487
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.54196
PLS1 plastin 1 -2.54061
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.53762
WDR73 WD repeat domain 73 -2.53606
SOD1 superoxide dismutase 1, soluble -2.53255
TMEM160 transmembrane protein 160 -2.53072
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.53061
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.52995
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.52991
COQ3 coenzyme Q3 methyltransferase -2.52798
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.52683
MICB MHC class I polypeptide-related sequence B -2.52544
CKAP2 cytoskeleton associated protein 2 -2.52469
OAZ2 ornithine decarboxylase antizyme 2 -2.5241
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -2.52328
COMMD9 COMM domain containing 9 -2.51928
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.51652
MAD2L1BP MAD2L1 binding protein -2.51598
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -2.51571
GEMIN6 gem (nuclear organelle) associated protein 6 -2.50953
MPC2 mitochondrial pyruvate carrier 2 -2.50709
TRA2B transformer 2 beta homolog (Drosophila) -2.50632
UNG uracil-DNA glycosylase -2.50615
SUMO2 small ubiquitin-like modifier 2 -2.49992
PYCR3 pyrroline-5-carboxylate reductase 3 -2.49848
HMGN2 high mobility group nucleosomal binding domain 2 -2.49746
COX7B cytochrome c oxidase subunit VIIb -2.49468
RBM8A RNA binding motif protein 8A -2.49256
DCAF7 DDB1 and CUL4 associated factor 7 -2.47715
MRPL19 mitochondrial ribosomal protein L19 -2.47583
RITA1 RBPJ interacting and tubulin associated 1 -2.47524
RBL1 retinoblastoma-like 1 -2.47438
LAPTM4B lysosomal protein transmembrane 4 beta -2.47356
XYLT2 xylosyltransferase II -2.47242
GPRC5C G protein-coupled receptor, class C, group 5, member C -2.47184
FAT2 FAT atypical cadherin 2 -2.46973
CENPN centromere protein N -2.46963
NLRP2B NLR family pyrin domain containing 2B -2.46119
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.45919
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.45813
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.45742
SZRD1 SUZ RNA binding domain containing 1 -2.4548
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.452
FOXC1 forkhead box C1 -2.45136
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.44827
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.44347
CYB561D2 cytochrome b561 family, member D2 -2.44308
PFAS phosphoribosylformylglycinamidine synthase -2.44107
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -2.43838
KIF14 kinesin family member 14 -2.42982
CHMP6 charged multivesicular body protein 6 -2.42979
FBXO34 F-box protein 34 -2.42293
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.42231
LIMD2 LIM domain containing 2 -2.42188
FTSJ3 FtsJ homolog 3 (E. coli) -2.42108
DSCC1 DNA replication and sister chromatid cohesion 1 -2.42045
NUP93 nucleoporin 93kDa -2.41571
AQP3 aquaporin 3 (Gill blood group) -2.41569
TSPAN6 tetraspanin 6 -2.41482
CHEK1 checkpoint kinase 1 -2.41156
SCGB1D1 secretoglobin, family 1D, member 1 -2.40015
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.39877
BLTP2 bridge-like lipid transfer protein family member 2 -2.3974
ZNF45 zinc finger protein 45 -2.38854
SPDL1 spindle apparatus coiled-coil protein 1 -2.38832
CASP8AP2 caspase 8 associated protein 2 -2.37849
DDB2 damage-specific DNA binding protein 2, 48kDa -2.37369
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -2.3714
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.36983
CDK1 cyclin-dependent kinase 1 -2.36823
TFDP1 transcription factor Dp-1 -2.36565
ZWINT ZW10 interacting kinetochore protein -2.36561
KREMEN2 kringle containing transmembrane protein 2 -2.3612
THEM6 thioesterase superfamily member 6 -2.3605
ZSCAN5A zinc finger and SCAN domain containing 5A -2.35959
TIPIN TIMELESS interacting protein -2.35863
DUT deoxyuridine triphosphatase -2.35834
ZNF200 zinc finger protein 200 -2.35648
GDAP1 ganglioside induced differentiation associated protein 1 -2.35416
ARRB1 arrestin, beta 1 -2.35377
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.3515
FBXO5 F-box protein 5 -2.3497
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.34816
TOE1 target of EGR1, member 1 (nuclear) -2.34806
VPS26C VPS26 endosomal protein sorting factor C -2.34656
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.34635
LYPLA2 lysophospholipase II -2.34617
KIF22 kinesin family member 22 -2.34363
UNC119 unc-119 homolog (C. elegans) -2.34245
HDAC3 histone deacetylase 3 -2.34015
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.33892
SDF2 stromal cell-derived factor 2 -2.33801
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -2.33593
GTF2A2 general transcription factor IIA, 2, 12kDa -2.3349
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.3344
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.33114
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.33037
BORA bora, aurora kinase A activator -2.32977
STEAP4 STEAP family member 4 -2.32151
BARD1 BRCA1 associated RING domain 1 -2.32092
ZNF557 zinc finger protein 557 -2.3209
CDC23 cell division cycle 23 -2.31894
LOC102724594 splicing factor U2AF 35 kDa subunit -2.31343
RIOX1 ribosomal oxygenase 1 -2.31241
RHOBTB2 Rho-related BTB domain containing 2 -2.31174
CIC capicua transcriptional repressor -2.31125
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.30226
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -2.30196
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.30007
HSPA1A heat shock 70kDa protein 1A -2.29712
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -2.28963
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.27845
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.27817
FTO fat mass and obesity associated -2.27703
KIF4A kinesin family member 4A -2.27559
ORC6 origin recognition complex, subunit 6 -2.27545
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -2.27489
CCDC86 coiled-coil domain containing 86 -2.27446
PSRC1 proline/serine-rich coiled-coil 1 -2.27235
HELZ helicase with zinc finger -2.26939
CDKN3 cyclin-dependent kinase inhibitor 3 -2.26753
CDT1 chromatin licensing and DNA replication factor 1 -2.26458
DPYD dihydropyrimidine dehydrogenase -2.2627
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.26254
SLC12A9 solute carrier family 12, member 9 -2.2624
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.26235
ZNF148 zinc finger protein 148 -2.26234
ZNF324B zinc finger protein 324B -2.26176
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.26116
PBK PDZ binding kinase -2.25447
TSC22D3 TSC22 domain family, member 3 -2.25339
FBXO3 F-box protein 3 -2.25252
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.24987
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.24984
IL27RA interleukin 27 receptor, alpha -2.24958
GRAMD1B GRAM domain containing 1B -2.24877
MSMB microseminoprotein, beta- -2.24792
VBP1 von Hippel-Lindau binding protein 1 -2.24483
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -2.24011
KLHDC3 kelch domain containing 3 -2.23871
KDM3B lysine (K)-specific demethylase 3B -2.23349
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.23327
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.23179
NEK2 NIMA-related kinase 2 -2.22727
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.22184
RPP30 ribonuclease P/MRP 30kDa subunit -2.21988
TMCO1 transmembrane and coiled-coil domains 1 -2.21827
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -2.2182
JRK Jrk homolog (mouse) -2.21696
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.21658
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -2.2165
ARHGAP11A Rho GTPase activating protein 11A -2.21455
SRSF7 serine/arginine-rich splicing factor 7 -2.21163
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.21142
HSPE1 heat shock 10kDa protein 1 -2.20936
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.20884
CSNK1G2 casein kinase 1, gamma 2 -2.20849
APEH acylaminoacyl-peptide hydrolase -2.20692
TCTN1 tectonic family member 1 -2.20598
RMI1 RecQ mediated genome instability 1 -2.2013
TMT1A thiol methyltransferase 1A -2.1995
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.19929
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.19607
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.19223
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -2.19219
WASHC5 WASH complex subunit 5 -2.1911
IRX5 iroquois homeobox 5 -2.19054
TACC3 transforming, acidic coiled-coil containing protein 3 -2.19026
SYBU syntabulin (syntaxin-interacting) -2.18957
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.18786
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.18743
TMEM106C transmembrane protein 106C -2.18483
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.18299
PRMT1 protein arginine methyltransferase 1 -2.18194
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -2.18129
FANCA Fanconi anemia, complementation group A -2.18007
STEAP3 STEAP family member 3, metalloreductase -2.179
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.17877
RANBP3 RAN binding protein 3 -2.17527
TMEM126B transmembrane protein 126B -2.17513
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -2.17366
SGSH N-sulfoglucosamine sulfohydrolase -2.16798
TUBA1A tubulin, alpha 1a -2.1679
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.16779
PPP5C protein phosphatase 5, catalytic subunit -2.16624
TMEM11 transmembrane protein 11 -2.16534
ZDHHC13 zinc finger, DHHC-type containing 13 -2.16449
ZNF219 zinc finger protein 219 -2.16205
PRCC papillary renal cell carcinoma (translocation-associated) -2.1545
TRAK2 trafficking protein, kinesin binding 2 -2.15436
PPT2 palmitoyl-protein thioesterase 2 -2.15038
RAB20 RAB20, member RAS oncogene family -2.14847
WNT4 wingless-type MMTV integration site family, member 4 -2.1474
PRPF4 pre-mRNA processing factor 4 -2.14658
THAP11 THAP domain containing 11 -2.14446
PSMC3IP PSMC3 interacting protein -2.1433
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.14267
MRPL46 mitochondrial ribosomal protein L46 -2.1355
ASB6 ankyrin repeat and SOCS box containing 6 -2.13526
KIFC1 kinesin family member C1 -2.13408
MEPCE methylphosphate capping enzyme -2.13034
ZNF428 zinc finger protein 428 -2.13011
SKIC8 SKI8 subunit of superkiller complex -2.12713
ZSCAN16 zinc finger and SCAN domain containing 16 -2.12571
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -2.12553
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.12494
SERF1A small EDRK-rich factor 1A (telomeric) -2.12285
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.12218
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 -2.12083
MPDU1 mannose-P-dolichol utilization defect 1 -2.12024
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -2.11944
HMGB3 high mobility group box 3 -2.11459
CD180 CD180 molecule -2.11179
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.11162
BAG3 BCL2-associated athanogene 3 -2.10637
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.10034
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.09916
ERH enhancer of rudimentary homolog (Drosophila) -2.09891
CYREN cell cycle regulator of NHEJ -2.09801
MRPL4 mitochondrial ribosomal protein L4 -2.0969
PEG10 paternally expressed 10 -2.09549
SECTM1 secreted and transmembrane 1 -2.09532
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.09496
UNKL unkempt family zinc finger-like -2.09311
NDRG3 NDRG family member 3 -2.0921
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.08893
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.08887
TRAIP TRAF interacting protein -2.08735
HDAC2 histone deacetylase 2 -2.08697
BAG1 BCL2-associated athanogene -2.0865
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -2.08603
HEATR3 HEAT repeat containing 3 -2.08556
EXOSC2 exosome component 2 -2.08446
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.08317
PMPCA peptidase (mitochondrial processing) alpha -2.08282
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C -2.08142
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.08129
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.07992
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.07658
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.07568
MCM9 minichromosome maintenance complex component 9 -2.07303
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -2.07164
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.07113
DCAF15 DDB1 and CUL4 associated factor 15 -2.0704
ZNF134 zinc finger protein 134 -2.0697
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.06774
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.06506
YJU2 YJU2 splicing factor homolog -2.0647
TSPAN4 tetraspanin 4 -2.06365
MKI67 marker of proliferation Ki-67 -2.06363
C1R complement component 1, r subcomponent -2.06228
ATAD5 ATPase family, AAA domain containing 5 -2.06216
CD4 CD4 molecule -2.06122
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.06094
RIN3 Ras and Rab interactor 3 -2.06025
PEX3 peroxisomal biogenesis factor 3 -2.05808
CERT1 ceramide transporter 1 -2.05716
GPATCH3 G patch domain containing 3 -2.05713
PRMT7 protein arginine methyltransferase 7 -2.05702
CREB1 cAMP responsive element binding protein 1 -2.05627
ASF1A anti-silencing function 1A histone chaperone -2.05562
HSPB11 heat shock protein family B (small), member 11 -2.05119
NCAPD3 non-SMC condensin II complex, subunit D3 -2.05008
PRKD3 protein kinase D3 -2.04535
PPP6R1 protein phosphatase 6, regulatory subunit 1 -2.04413
NDNF neuron-derived neurotrophic factor -2.0431
ZMYM1 zinc finger, MYM-type 1 -2.04297
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -2.04295
AURKA aurora kinase A -2.04206
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.03783
INTS5 integrator complex subunit 5 -2.03766
HYAL2 hyaluronoglucosaminidase 2 -2.03649
RRP1B ribosomal RNA processing 1B -2.0362
SLC44A4 solute carrier family 44, member 4 -2.03602
CBX3 chromobox homolog 3 -2.03306
TLE5 TLE family member 5, transcriptional modulator -2.03243
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.03054
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.02833
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -2.02714
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.02645
SATB1 SATB homeobox 1 -2.02408
FANCI Fanconi anemia, complementation group I -2.02301
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.02242
DOLK dolichol kinase -2.0209
PMF1-BGLAP PMF1-BGLAP readthrough -2.02024
VANGL1 VANGL planar cell polarity protein 1 -2.02006
MTMR14 myotubularin related protein 14 -2.01989
ETF1 eukaryotic translation termination factor 1 -2.01841
HSPA14 heat shock 70kDa protein 14 -2.01804
OSBPL11 oxysterol binding protein-like 11 -2.01768
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.0174
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.0162
ZBTB16 zinc finger and BTB domain containing 16 -2.01612
BORCS6 BLOC-1 related complex subunit 6 -2.01608
QPRT quinolinate phosphoribosyltransferase -2.01392
EML4 echinoderm microtubule associated protein like 4 -2.01391
GALK1 galactokinase 1 -2.01301
ASB13 ankyrin repeat and SOCS box containing 13 -2.0112
TUBA1C tubulin, alpha 1c -2.00955
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.00811
GLO1 glyoxalase I -2.00802
LAS1L LAS1-like (S. cerevisiae) -2.00799
PRUNE1 prune exopolyphosphatase 1 -2.00606
CDK2 cyclin-dependent kinase 2 -2.00583
DEPDC1 DEP domain containing 1 -2.00506
ARHGAP15 Rho GTPase activating protein 15 -2.00378
UFD1 ubiquitin recognition factor in ER associated degradation 1 -2.00247
RAB8A RAB8A, member RAS oncogene family -2.00061