CRCGN017_MCF10A.TP53.M_24H:A18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description galangin 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4.10137
CCL2 chemokine (C-C motif) ligand 2 3.74119
E2F2 E2F transcription factor 2 3.36332
SQOR sulfide quinone oxidoreductase 3.03123
ACAA1 acetyl-CoA acyltransferase 1 2.59171
COMP cartilage oligomeric matrix protein 2.4194
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.39272
TRIB3 tribbles pseudokinase 3 2.27236
TOMM34 translocase of outer mitochondrial membrane 34 2.24087
SYNGAP1 synaptic Ras GTPase activating protein 1 2.19337
CCDC85B coiled-coil domain containing 85B 2.10816

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.62
NUP85 nucleoporin 85kDa -3.56614
LAP3 leucine aminopeptidase 3 -3.43608
UFM1 ubiquitin-fold modifier 1 -3.33119
SLC35F2 solute carrier family 35, member F2 -3.06437
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.98812
HMG20B high mobility group 20B -2.67348
CTNND1 catenin (cadherin-associated protein), delta 1 -2.5744
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.56425
PCNA proliferating cell nuclear antigen -2.56104
ANXA2 annexin A2 -2.34011
LRP10 low density lipoprotein receptor-related protein 10 -2.10711
HSPA1A heat shock 70kDa protein 1A -2.1069
JPT1 Jupiter microtubule associated homolog 1 -2.07621
SUMO4 small ubiquitin-like modifier 4 -2.06521
DUSP14 dual specificity phosphatase 14 -2.04546
TMEM94 transmembrane protein 94 -2.03022
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.0177