CRCGN017_MCF10A.TP53.M_24H:A21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibenzo[a,l]pyrene 10.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TBPL1 TBP-like 1 4.18499
STK10 serine/threonine kinase 10 3.46332
COMP cartilage oligomeric matrix protein 2.84722
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.83058
TOMM34 translocase of outer mitochondrial membrane 34 2.52593
SNX11 sorting nexin 11 2.44604
SATB1 SATB homeobox 1 2.26835
FUBP3 far upstream element (FUSE) binding protein 3 2.0882
NFIL3 nuclear factor, interleukin 3 regulated 2.08443
NCK1 NCK adaptor protein 1 2.0764

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -5.08084
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.91344
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.73111
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.3093
CANT1 calcium activated nucleotidase 1 -3.28294
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.87455
RHOT2 ras homolog family member T2 -2.69835
RPP38 ribonuclease P/MRP 38kDa subunit -2.54705
GRWD1 glutamate-rich WD repeat containing 1 -2.46153
PCCB propionyl CoA carboxylase, beta polypeptide -2.21911
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -2.1818
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.15576
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.15239
RAD51C RAD51 paralog C -2.14811
KDM3A lysine (K)-specific demethylase 3A -2.09494
EIF3G eukaryotic translation initiation factor 3, subunit G -2.00216