| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ammonium-perfluorocaprylate 98.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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65 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | 4.79022 |
| MAP7 | microtubule-associated protein 7 | 4.25141 |
| APOE | apolipoprotein E | 3.67487 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 3.11037 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.98905 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2.86077 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.7954 |
| FAM20B | family with sequence similarity 20, member B | 2.73483 |
| PLS1 | plastin 1 | 2.67651 |
| CASC3 | cancer susceptibility candidate 3 | 2.47771 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | 2.45499 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 2.33236 |
| RANBP2 | RAN binding protein 2 | 2.33132 |
| GASK1B | golgi associated kinase 1B | 2.26189 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.22838 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 2.22296 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 2.21277 |
| NISCH | nischarin | 2.19005 |
| DUSP14 | dual specificity phosphatase 14 | 2.17414 |
| GSTA4 | glutathione S-transferase alpha 4 | 2.17353 |
| TRIM25 | tripartite motif containing 25 | 2.15737 |
| MORF4L2 | mortality factor 4 like 2 | 2.14452 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 2.13478 |
| POLR1F | RNA polymerase I subunit F | 2.12821 |
| LRRC31 | leucine rich repeat containing 31 | 2.11382 |
| NCBP3 | nuclear cap binding subunit 3 | 2.10099 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 2.0924 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 2.06801 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 2.0554 |
| CYTH1 | cytohesin 1 | 2.037 |
| JMJD1C | jumonji domain containing 1C | 2.02769 |
| ZNF589 | zinc finger protein 589 | 2.02055 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 2.0137 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 2.01269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -5.0616 |
| KIF14 | kinesin family member 14 | -4.10023 |
| CAB39 | calcium binding protein 39 | -4.06717 |
| TUBA4A | tubulin, alpha 4a | -3.72454 |
| CCDC86 | coiled-coil domain containing 86 | -3.677 |
| MTFR1 | mitochondrial fission regulator 1 | -3.50795 |
| BID | BH3 interacting domain death agonist | -3.49993 |
| RPN1 | ribophorin I | -3.39038 |
| PCNA | proliferating cell nuclear antigen | -3.32878 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.21396 |
| PRKX | protein kinase, X-linked | -2.54936 |
| DDRGK1 | DDRGK domain containing 1 | -2.49931 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.49597 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.46302 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.44063 |
| PANK2 | pantothenate kinase 2 | -2.42602 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.42508 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.3894 |
| MT1X | metallothionein 1X | -2.36965 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.34484 |
| ANXA8L1 | annexin A8-like 1 | -2.32177 |
| UMOD | uromodulin | -2.32012 |
| CBR3 | carbonyl reductase 3 | -2.17199 |
| RXYLT1 | ribitol xylosyltransferase 1 | -2.07933 |
| POLH | polymerase (DNA directed), eta | -2.07816 |
| EVPL | envoplakin | -2.04431 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.03625 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.02687 |
| SECTM1 | secreted and transmembrane 1 | -2.0142 |
| LRRC41 | leucine rich repeat containing 41 | -2.01134 |
| SMIM40 | small integral membrane protein 40 | -2.00676 |
