CRCGN017_MCF10A.TP53.M_24H:B03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 4.3493
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.31465
PDLIM1 PDZ and LIM domain 1 2.89945
TBX2 T-box 2 2.72018
SYNGAP1 synaptic Ras GTPase activating protein 1 2.48795
PLS1 plastin 1 2.10645

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -5.0187
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.6726
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -3.3577
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.81805
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.70387
BASP1 brain abundant, membrane attached signal protein 1 -2.5395
CBR3 carbonyl reductase 3 -2.40765
LOXL1 lysyl oxidase-like 1 -2.3158
SDF2L1 stromal cell-derived factor 2-like 1 -2.31535
LRRC41 leucine rich repeat containing 41 -2.1344
FLCN folliculin -2.11755
STARD8 StAR-related lipid transfer (START) domain containing 8 -2.11245
TCTA T-cell leukemia translocation altered -2.0878
TNN tenascin N -2.0572
BPHL biphenyl hydrolase-like (serine hydrolase) -2.052
SOX2 SRY (sex determining region Y)-box 2 -2.04803