CRCGN017_MCF10A.TP53.M_24H:B05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.60323
HBA1 hemoglobin, alpha 1 3.62198
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.66114
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.59181
DPY19L1 dpy-19-like 1 (C. elegans) 2.39141
SNAP25 synaptosomal-associated protein, 25kDa 2.15717
AGR2 anterior gradient 2 2.07642
KCTD11 potassium channel tetramerization domain containing 11 2.01176

decreased expression

Symbol Name Standardized Value
DNM1L dynamin 1-like -5.17586
MAPK13 mitogen-activated protein kinase 13 -4.86624
CCDC86 coiled-coil domain containing 86 -4.1686
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -3.93893
KRT14 keratin 14, type I -3.36625
RXYLT1 ribitol xylosyltransferase 1 -3.35318
CORO1A coronin, actin binding protein, 1A -3.27952
LGALSL lectin, galactoside-binding-like -3.11176
KDM3A lysine (K)-specific demethylase 3A -2.75754
PARP2 poly (ADP-ribose) polymerase 2 -2.72816
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.67341
CAPRIN2 caprin family member 2 -2.64335
NT5DC2 5'-nucleotidase domain containing 2 -2.62131
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.53698
LMBR1L limb development membrane protein 1-like -2.35761
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.31542
WASHC3 WASH complex subunit 3 -2.30618
ATP11B ATPase, class VI, type 11B -2.27312
ERGIC2 ERGIC and golgi 2 -2.24791
MED21 mediator complex subunit 21 -2.10773
ZNF165 zinc finger protein 165 -2.107