CRCGN017_MCF10A.TP53.M_24H:B08 Gene Set
Genes
42 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
4.83301
|
|
SPAG4
|
sperm associated antigen 4
|
4.64452
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.30356
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.84594
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.74887
|
|
HOXA5
|
homeobox A5
|
3.63504
|
|
TBPL1
|
TBP-like 1
|
3.49043
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.71422
|
|
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
2.54748
|
|
PRKCH
|
protein kinase C, eta
|
2.49875
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
2.31579
|
|
MMP1
|
matrix metallopeptidase 1
|
2.15325
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.10287
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.08004
|
|
B4GAT1
|
beta-1,4-glucuronyltransferase 1
|
2.05639
|
|
OTUD3
|
OTU deubiquitinase 3
|
2.03961
|
|
CLCC1
|
chloride channel CLIC-like 1
|
2.02979
|
|
EXOSC9
|
exosome component 9
|
2.00579
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-4.64225
|
|
CCNB1
|
cyclin B1
|
-3.98881
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.57016
|
|
GRN
|
granulin
|
-3.28873
|
|
S100A8
|
S100 calcium binding protein A8
|
-3.25393
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.96378
|
|
TUBA4A
|
tubulin, alpha 4a
|
-2.83117
|
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3
|
-2.81929
|
|
PSMG1
|
proteasome (prosome, macropain) assembly chaperone 1
|
-2.76601
|
|
SPAG7
|
sperm associated antigen 7
|
-2.63129
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.62777
|
|
CNKSR1
|
connector enhancer of kinase suppressor of Ras 1
|
-2.4225
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
-2.35146
|
|
ANXA8L1
|
annexin A8-like 1
|
-2.32154
|
|
SDC1
|
syndecan 1
|
-2.32023
|
|
NAGK
|
N-acetylglucosamine kinase
|
-2.27214
|
|
TKT
|
transketolase
|
-2.25462
|
|
TMEM40
|
transmembrane protein 40
|
-2.23927
|
|
ILK
|
integrin-linked kinase
|
-2.23813
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.21509
|
|
RAB25
|
RAB25, member RAS oncogene family
|
-2.20725
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.18736
|
|
CYB5A
|
cytochrome b5 type A (microsomal)
|
-2.10822
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.09741
|
