CRCGN017_MCF10A.TP53.M_24H:B10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-ethyl-n-nitrosourea 107.62 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

48 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RTN2 reticulon 2 3.69679
AGR2 anterior gradient 2 2.98678
WIF1 WNT inhibitory factor 1 2.63046
TLR4 toll-like receptor 4 2.60582
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.55436
CNRIP1 cannabinoid receptor interacting protein 1 2.41752
CCNA1 cyclin A1 2.26103
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.25722
SLC25A40 solute carrier family 25, member 40 2.2318
ATP5F1B ATP synthase F1 subunit beta 2.16672
MCUR1 mitochondrial calcium uniporter regulator 1 2.15293
FAR2 fatty acyl CoA reductase 2 2.06615
ADGRE5 adhesion G protein-coupled receptor E5 2.05233
ADCY7 adenylate cyclase 7 2.03412
FAT4 FAT atypical cadherin 4 2.02228

decreased expression

Symbol Name Standardized Value
NUP85 nucleoporin 85kDa -4.42674
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -4.04347
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.90294
MRPL58 mitochondrial ribosomal protein L58 -3.69131
IFRD2 interferon-related developmental regulator 2 -3.5638
MRPS7 mitochondrial ribosomal protein S7 -3.53904
APEH acylaminoacyl-peptide hydrolase -3.19453
ACOX1 acyl-CoA oxidase 1, palmitoyl -3.05143
ATF5 activating transcription factor 5 -2.97958
TIMP1 TIMP metallopeptidase inhibitor 1 -2.85298
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.75827
KCTD2 potassium channel tetramerization domain containing 2 -2.7529
NT5C 5', 3'-nucleotidase, cytosolic -2.63618
TMEM115 transmembrane protein 115 -2.43383
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -2.39197
SAP30BP SAP30 binding protein -2.30165
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.2663
HROB homologous recombination factor with OB-fold -2.23987
TMEM94 transmembrane protein 94 -2.23486
FHIT fragile histidine triad -2.19787
SNAP29 synaptosomal-associated protein, 29kDa -2.19776
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.18942
TCEAL2 transcription elongation factor A (SII)-like 2 -2.16702
SUMO4 small ubiquitin-like modifier 4 -2.15353
SLC38A12 solute carrier family 38 member 12 -2.14894
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.13129
CDR2L cerebellar degeneration-related protein 2-like -2.12846
APOL3 apolipoprotein L, 3 -2.11455
PNMA3 paraneoplastic Ma antigen 3 -2.10947
TKT transketolase -2.06569
TPRA1 transmembrane protein, adipocyte asscociated 1 -2.01884
MGMT O-6-methylguanine-DNA methyltransferase -2.01063
CLDN9 claudin 9 -2.00918