| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-ethyl-n-nitrosourea 35.87 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.3691 |
| KDM5D | lysine (K)-specific demethylase 5D | 3.48577 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.48095 |
| E2F2 | E2F transcription factor 2 | 3.31212 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.79126 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.71159 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 2.61392 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.58059 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.57004 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.48394 |
| PRM2 | protamine 2 | 2.43144 |
| MTA2 | metastasis associated 1 family, member 2 | 2.3957 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 2.37556 |
| AGR2 | anterior gradient 2 | 2.30234 |
| UTRN | utrophin | 2.2289 |
| BAG4 | BCL2-associated athanogene 4 | 2.15186 |
| ODF1 | outer dense fiber of sperm tails 1 | 2.1441 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.14316 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) | 2.13251 |
| TRIM38 | tripartite motif containing 38 | 2.12134 |
| FER | fer (fps/fes related) tyrosine kinase | 2.10856 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.08965 |
| TADA2A | transcriptional adaptor 2A | 2.0724 |
| CUL2 | cullin 2 | 2.04411 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 2.03452 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | 2.00754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPS2 | mitochondrial ribosomal protein S2 | -4.0415 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.49586 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.47682 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -3.44238 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -3.41155 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.34728 |
| TXNDC9 | thioredoxin domain containing 9 | -3.14045 |
| TBCB | tubulin folding cofactor B | -3.01162 |
| VWA1 | von Willebrand factor A domain containing 1 | -2.78651 |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein | -2.72448 |
| TCTA | T-cell leukemia translocation altered | -2.39056 |
| PUDP | pseudouridine 5'-phosphatase | -2.31717 |
| TUBB6 | tubulin, beta 6 class V | -2.28673 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -2.27007 |
| KRT14 | keratin 14, type I | -2.26676 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -2.25148 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.20752 |
| ZIC1 | Zic family member 1 | -2.16125 |
| RBM42 | RNA binding motif protein 42 | -2.15535 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.12547 |
| IRF9 | interferon regulatory factor 9 | -2.10458 |
| C1QBP | complement component 1, q subcomponent binding protein | -2.10401 |
| LIN37 | lin-37 DREAM MuvB core complex component | -2.09858 |
| CAPNS1 | calpain, small subunit 1 | -2.07394 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -2.06055 |
| ANXA2 | annexin A2 | -2.04015 |
| TUBA4A | tubulin, alpha 4a | -2.02348 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -2.02344 |
| PAEP | progestagen-associated endometrial protein | -2.00192 |
