CRCGN017_MCF10A.TP53.M_24H:B13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 100.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.2301
CARMIL1 capping protein regulator and myosin 1 linker 1 5.19327
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.32038
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.71033
GPER1 G protein-coupled estrogen receptor 1 3.37192
MCUR1 mitochondrial calcium uniporter regulator 1 2.9978
KLHL21 kelch-like family member 21 2.87489
TLCD3A TLC domain containing 3A 2.45917
PLS1 plastin 1 2.27621
ACAA1 acetyl-CoA acyltransferase 1 2.26705
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.14936

decreased expression

Symbol Name Standardized Value
TCTA T-cell leukemia translocation altered -5.3533
HMG20B high mobility group 20B -5.28252
PCNA proliferating cell nuclear antigen -4.81167
CLEC11A C-type lectin domain family 11, member A -2.37102
PCCB propionyl CoA carboxylase, beta polypeptide -2.27029
NGRN neugrin, neurite outgrowth associated -2.17833
BAD BCL2-associated agonist of cell death -2.10753
UFM1 ubiquitin-fold modifier 1 -2.04797