CRCGN017_MCF10A.TP53.M_24H:B15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 4.66529
C2CD2 C2 calcium-dependent domain containing 2 4.63814
SPAG4 sperm associated antigen 4 4.5523
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.65834
MAST2 microtubule associated serine/threonine kinase 2 3.20556
IGHMBP2 immunoglobulin mu binding protein 2 2.58244
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.48799
LTN1 listerin E3 ubiquitin protein ligase 1 2.38892
EVL Enah/Vasp-like 2.09223
TOMM34 translocase of outer mitochondrial membrane 34 2.0741
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.04126
COQ8A coenzyme Q8A 2.02061

decreased expression

Symbol Name Standardized Value
TRAPPC3 trafficking protein particle complex 3 -4.4902
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.47292
ILK integrin-linked kinase -2.15969
MPHOSPH8 M-phase phosphoprotein 8 -2.15839
KIAA0319L KIAA0319-like -2.14562
HSPA1A heat shock 70kDa protein 1A -2.08492