| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | flutamide 100.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 4.79214 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 4.67912 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 4.24684 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.448 |
| E2F2 | E2F transcription factor 2 | 3.40614 |
| IL1B | interleukin 1, beta | 3.33619 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.21831 |
| HMGA2 | high mobility group AT-hook 2 | 3.19531 |
| EGR1 | early growth response 1 | 2.93344 |
| GLRX | glutaredoxin (thioltransferase) | 2.7977 |
| CDCA4 | cell division cycle associated 4 | 2.66233 |
| TBX2 | T-box 2 | 2.63957 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.60889 |
| RPL39L | ribosomal protein L39-like | 2.59791 |
| GARS1 | glycyl-tRNA synthetase 1 | 2.57788 |
| COL4A1 | collagen, type IV, alpha 1 | 2.44016 |
| CETN3 | centrin, EF-hand protein, 3 | 2.39716 |
| STX1A | syntaxin 1A (brain) | 2.37946 |
| CADM1 | cell adhesion molecule 1 | 2.37771 |
| NUCB2 | nucleobindin 2 | 2.3617 |
| TRIB3 | tribbles pseudokinase 3 | 2.35851 |
| DUSP4 | dual specificity phosphatase 4 | 2.33767 |
| CDK7 | cyclin-dependent kinase 7 | 2.30385 |
| FHL2 | four and a half LIM domains 2 | 2.2896 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.24363 |
| MYLK | myosin light chain kinase | 2.23622 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | 2.236 |
| RPGR | retinitis pigmentosa GTPase regulator | 2.22406 |
| FAM169A | family with sequence similarity 169, member A | 2.21876 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.19014 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 2.15129 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.11422 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.07764 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.05949 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.05893 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 2.01803 |
| PCDHB11 | protocadherin beta 11 | 2.00118 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.87117 |
| ADRB2 | adrenoceptor beta 2, surface | -3.69129 |
| PRR15L | proline rich 15-like | -3.2304 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -3.21322 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.2127 |
| ATF5 | activating transcription factor 5 | -3.17662 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -3.08962 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -2.99406 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -2.76734 |
| TES | testin LIM domain protein | -2.66889 |
| ABHD4 | abhydrolase domain containing 4 | -2.60304 |
| R3HCC1 | R3H domain and coiled-coil containing 1 | -2.53654 |
| GOLT1B | golgi transport 1B | -2.50983 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -2.40116 |
| TRAPPC2L | trafficking protein particle complex 2-like | -2.36452 |
| ARPC4-TTLL3 | ARPC4-TTLL3 readthrough | -2.32247 |
| CCDC6 | coiled-coil domain containing 6 | -2.32213 |
| KIF14 | kinesin family member 14 | -2.3133 |
| KRABD4 | KRAB domain containing 4 | -2.25948 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.24493 |
| NOP14 | NOP14 nucleolar protein | -2.21186 |
| ANKRD10 | ankyrin repeat domain 10 | -2.17815 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | -2.14322 |
| INTS5 | integrator complex subunit 5 | -2.13947 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.13435 |
| CORO1A | coronin, actin binding protein, 1A | -2.13352 |
| CDC73 | cell division cycle 73 | -2.12116 |
| FAM13B | family with sequence similarity 13, member B | -2.11428 |
| ADI1 | acireductone dioxygenase 1 | -2.07915 |
| TMEM50A | transmembrane protein 50A | -2.0733 |
| RNASE7 | ribonuclease, RNase A family, 7 | -2.05426 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | -2.01848 |
