CRCGN017_MCF10A.TP53.M_24H:B18 Gene Set
Genes
43 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AGR2
|
anterior gradient 2
|
3.52771
|
|
SPAG4
|
sperm associated antigen 4
|
3.44008
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
3.34575
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
3.21201
|
|
CDCA4
|
cell division cycle associated 4
|
3.19219
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.18386
|
|
SLC1A4
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
|
3.10245
|
|
MAN2B2
|
mannosidase, alpha, class 2B, member 2
|
2.83933
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.56879
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.43559
|
|
EPCAM
|
epithelial cell adhesion molecule
|
2.3574
|
|
CHEK1
|
checkpoint kinase 1
|
2.34831
|
|
F2R
|
coagulation factor II (thrombin) receptor
|
2.3405
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.17575
|
|
SYBU
|
syntabulin (syntaxin-interacting)
|
2.13593
|
|
SERPINA5
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
|
2.13469
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.0511
|
|
CHSY1
|
chondroitin sulfate synthase 1
|
2.00464
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HAT1
|
histone acetyltransferase 1
|
-3.68381
|
|
PLK1
|
polo-like kinase 1
|
-3.35426
|
|
HMG20B
|
high mobility group 20B
|
-3.33475
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.33456
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-3.10453
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.10357
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-3.03384
|
|
CCNB2
|
cyclin B2
|
-2.696
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-2.54412
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.46929
|
|
BSG
|
basigin (Ok blood group)
|
-2.41973
|
|
COL9A1
|
collagen, type IX, alpha 1
|
-2.37827
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.35817
|
|
PRUNE2
|
prune homolog 2 (Drosophila)
|
-2.30459
|
|
TROAP
|
trophinin associated protein
|
-2.29058
|
|
ACTC1
|
actin, alpha, cardiac muscle 1
|
-2.14764
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.14221
|
|
SNCG
|
synuclein, gamma (breast cancer-specific protein 1)
|
-2.11844
|
|
AK8
|
adenylate kinase 8
|
-2.11348
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.08885
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.06453
|
|
DES
|
desmin
|
-2.05309
|
|
RND1
|
Rho family GTPase 1
|
-2.02816
|
|
FLNC
|
filamin C, gamma
|
-2.02036
|
|
ASCC1
|
activating signal cointegrator 1 complex subunit 1
|
-2.01449
|