CRCGN017_MCF10A.TP53.M_24H:B21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitropyrene 11.01 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.99973
ARID5B AT rich interactive domain 5B (MRF1-like) 4.97741
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.66791
ABHD4 abhydrolase domain containing 4 4.05934
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.74566
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.48149
KDM5D lysine (K)-specific demethylase 5D 2.46619
NSG2 neuronal vesicle trafficking associated 2 2.29076
RFC4 replication factor C (activator 1) 4, 37kDa 2.27852
CDCA4 cell division cycle associated 4 2.22957
GSTZ1 glutathione S-transferase zeta 1 2.14403
KCNIP2 Kv channel interacting protein 2 2.10435
SNX7 sorting nexin 7 2.02394
FKBP14 FK506 binding protein 14, 22 kDa 2.00313
USP9Y ubiquitin specific peptidase 9, Y-linked 2.00102

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.2542
HMG20B high mobility group 20B -5.1529
COG2 component of oligomeric golgi complex 2 -4.64148
KDM3A lysine (K)-specific demethylase 3A -3.37537
CD320 CD320 molecule -3.02115
MSN moesin -2.789
KRT14 keratin 14, type I -2.74959
TEX10 testis expressed 10 -2.41749
POLR1D polymerase (RNA) I polypeptide D, 16kDa -2.35787
YME1L1 YME1-like 1 ATPase -2.28208
NR3C2 nuclear receptor subfamily 3, group C, member 2 -2.18675
PIBF1 progesterone immunomodulatory binding factor 1 -2.07098
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.06321
KIF14 kinesin family member 14 -2.0172
INTS14 integrator complex subunit 14 -2.00794