CRCGN017_MCF10A.TP53.M_24H:B22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminodiphenyl 98.46 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.11222
WFS1 Wolfram syndrome 1 (wolframin) 3.9501
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.97691
AGR2 anterior gradient 2 2.89098
KDM5D lysine (K)-specific demethylase 5D 2.67069
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.65382
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.46092
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.38736
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.25436

decreased expression

Symbol Name Standardized Value
CD58 CD58 molecule -4.13797
LYPLA1 lysophospholipase I -3.79595
SMC1A structural maintenance of chromosomes 1A -2.8095
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.47209
KDM3A lysine (K)-specific demethylase 3A -2.45451
KDM5C lysine (K)-specific demethylase 5C -2.37704
UBA1 ubiquitin-like modifier activating enzyme 1 -2.25572
IGSF3 immunoglobulin superfamily, member 3 -2.12952
SDC1 syndecan 1 -2.062