CRCGN017_MCF10A.TP53.M_24H:C09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sr1664 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.99177
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 4.55089
LYN LYN proto-oncogene, Src family tyrosine kinase 3.27071
RBP4 retinol binding protein 4, plasma 2.9824
SNX11 sorting nexin 11 2.85831
BZW2 basic leucine zipper and W2 domains 2 2.82109
TPD52L2 tumor protein D52-like 2 2.68742
CCNF cyclin F 2.62676
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.60346
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.55951
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.31798
SYNGAP1 synaptic Ras GTPase activating protein 1 2.30474
RSF1 remodeling and spacing factor 1 2.21598
AAMDC adipogenesis associated, Mth938 domain containing 2.19657

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -3.39815
LMTK1 lemur tail kinase 1 -2.34537
BPHL biphenyl hydrolase-like (serine hydrolase) -2.20084
DKKL1 dickkopf-like 1 -2.16852
KRT14 keratin 14, type I -2.15977
ZNF76 zinc finger protein 76 -2.06457
TCTA T-cell leukemia translocation altered -2.01848