CRCGN017_MCF10A.TP53.M_24H:C11 Gene Set
Genes
45 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AGR2
|
anterior gradient 2
|
6.61843
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
3.95562
|
|
OXSR1
|
oxidative stress responsive 1
|
3.79887
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
3.76153
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.70089
|
|
NRBF2
|
nuclear receptor binding factor 2
|
3.27408
|
|
E2F2
|
E2F transcription factor 2
|
3.02277
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.83818
|
|
GATA3
|
GATA binding protein 3
|
2.80414
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.60034
|
|
TBPL1
|
TBP-like 1
|
2.55888
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.34762
|
|
RBP4
|
retinol binding protein 4, plasma
|
2.32601
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.25622
|
|
FCHO1
|
FCH domain only 1
|
2.12031
|
|
CCNT1
|
cyclin T1
|
2.1119
|
|
HSD17B3
|
hydroxysteroid (17-beta) dehydrogenase 3
|
2.08065
|
|
FAM168B
|
family with sequence similarity 168, member B
|
2.064
|
|
NXT1
|
nuclear transport factor 2-like export factor 1
|
2.05859
|
|
DCLRE1B
|
DNA cross-link repair 1B
|
2.0547
|
|
PADI3
|
peptidyl arginine deiminase, type III
|
2.04863
|
|
TCEA2
|
transcription elongation factor A (SII), 2
|
2.04485
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.02402
|
|
GRPEL1
|
GrpE-like 1, mitochondrial (E. coli)
|
2.02199
|
|
SOSTDC1
|
sclerostin domain containing 1
|
2.01959
|
|
ABRAXAS2
|
abraxas 2, BRISC complex subunit
|
2.00468
|
|
TMEM185B
|
transmembrane protein 185B
|
2.00385
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMG20B
|
high mobility group 20B
|
-6.65765
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-5.25243
|
|
HOXA5
|
homeobox A5
|
-5.06152
|
|
NUP85
|
nucleoporin 85kDa
|
-3.05083
|
|
KIF14
|
kinesin family member 14
|
-2.93575
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.40626
|
|
TKT
|
transketolase
|
-2.26294
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-2.22043
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-2.21841
|
|
BABAM1
|
BRISC and BRCA1 A complex member 1
|
-2.20905
|
|
PNRC1
|
proline-rich nuclear receptor coactivator 1
|
-2.20646
|
|
LLGL2
|
lethal giant larvae homolog 2 (Drosophila)
|
-2.18455
|
|
DELE1
|
DAP3 binding cell death enhancer 1
|
-2.16043
|
|
SH3GL1
|
SH3-domain GRB2-like 1
|
-2.09904
|
|
ZHX2
|
zinc fingers and homeoboxes 2
|
-2.07938
|
|
LZTR1
|
leucine-zipper-like transcription regulator 1
|
-2.03496
|
|
APBA3
|
amyloid beta (A4) precursor protein-binding, family A, member 3
|
-2.02901
|
|
STK16
|
serine/threonine kinase 16
|
-2.01605
|
