CRCGN017_MCF10A.TP53.M_24H:C12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description lg100268 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.11573
TCEA2 transcription elongation factor A (SII), 2 3.59087
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.7916
KLHL9 kelch-like family member 9 2.49242
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.43791
PRKCH protein kinase C, eta 2.42319
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.07675

decreased expression

Symbol Name Standardized Value
CD58 CD58 molecule -3.2987
KIF14 kinesin family member 14 -2.94376
RXYLT1 ribitol xylosyltransferase 1 -2.54001
HSPA8 heat shock 70kDa protein 8 -2.45651
KRT14 keratin 14, type I -2.12437
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.01222
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.00797