CRCGN017_MCF10A.TP53.M_24H:C14 Gene Set
Genes
42 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TCEA2
|
transcription elongation factor A (SII), 2
|
5.67986
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.61784
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
4.32586
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.27688
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
3.71282
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
3.09581
|
|
HBA1
|
hemoglobin, alpha 1
|
2.87244
|
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa
|
2.66175
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.6109
|
|
FZD7
|
frizzled class receptor 7
|
2.5781
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.56121
|
|
SBNO1
|
strawberry notch homolog 1 (Drosophila)
|
2.54799
|
|
SSR3
|
signal sequence receptor, gamma (translocon-associated protein gamma)
|
2.48394
|
|
NUTF2
|
nuclear transport factor 2
|
2.39968
|
|
IL1B
|
interleukin 1, beta
|
2.35316
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.20184
|
|
EVL
|
Enah/Vasp-like
|
2.18867
|
|
LBR
|
lamin B receptor
|
2.10213
|
|
TBPL1
|
TBP-like 1
|
2.09866
|
|
SRSF6
|
serine/arginine-rich splicing factor 6
|
2.09223
|
|
DBR1
|
debranching RNA lariats 1
|
2.05709
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.52001
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-4.65332
|
|
UFM1
|
ubiquitin-fold modifier 1
|
-4.5742
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.07282
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-3.55801
|
|
KRT14
|
keratin 14, type I
|
-3.27316
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.88716
|
|
MALT1
|
MALT1 paracaspase
|
-2.52661
|
|
ZC2HC1A
|
zinc finger, C2HC-type containing 1A
|
-2.29577
|
|
NRIP2
|
nuclear receptor interacting protein 2
|
-2.24382
|
|
ZNF606
|
zinc finger protein 606
|
-2.22502
|
|
CLDN5
|
claudin 5
|
-2.19495
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.16719
|
|
HSD17B14
|
hydroxysteroid (17-beta) dehydrogenase 14
|
-2.15981
|
|
TOP6BL
|
TOP6B like initiator of meiotic double strand breaks
|
-2.13657
|
|
ROBO4
|
roundabout, axon guidance receptor, homolog 4 (Drosophila)
|
-2.08374
|
|
RBM41
|
RNA binding motif protein 41
|
-2.05748
|
|
ZNF696
|
zinc finger protein 696
|
-2.02978
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.02124
|
|
PELI1
|
pellino E3 ubiquitin protein ligase 1
|
-2.00585
|
|
CDR2L
|
cerebellar degeneration-related protein 2-like
|
-2.00077
|
