CRCGN017_MCF10A.TP53.M_24H:C16 Gene Set
Genes
44 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
4.79761
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.57335
|
|
BMP4
|
bone morphogenetic protein 4
|
2.85322
|
|
NSG2
|
neuronal vesicle trafficking associated 2
|
2.62651
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.49054
|
|
SYT2
|
synaptotagmin II
|
2.45552
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.38962
|
|
TBPL1
|
TBP-like 1
|
2.33664
|
|
NPY
|
neuropeptide Y
|
2.21315
|
|
MRPL17
|
mitochondrial ribosomal protein L17
|
2.19759
|
|
SYT1
|
synaptotagmin I
|
2.18806
|
|
ATP6V1F
|
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
|
2.17715
|
|
CCNE2
|
cyclin E2
|
2.15478
|
|
SV2B
|
synaptic vesicle glycoprotein 2B
|
2.11985
|
|
DDX39A
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
|
2.10003
|
|
BCS1L
|
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
|
2.06665
|
|
ITGB3BP
|
integrin beta 3 binding protein (beta3-endonexin)
|
2.03602
|
|
ORC6
|
origin recognition complex, subunit 6
|
2.01998
|
|
EVL
|
Enah/Vasp-like
|
2.005
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-7.72824
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-6.7552
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-3.93043
|
|
GPAA1
|
glycosylphosphatidylinositol anchor attachment 1
|
-3.91489
|
|
LDHD
|
lactate dehydrogenase D
|
-3.23126
|
|
KRT14
|
keratin 14, type I
|
-3.1662
|
|
GSDMD
|
gasdermin D
|
-2.97885
|
|
DGAT1
|
diacylglycerol O-acyltransferase 1
|
-2.89097
|
|
PYCR3
|
pyrroline-5-carboxylate reductase 3
|
-2.77784
|
|
SLC52A2
|
solute carrier family 52 (riboflavin transporter), member 2
|
-2.77213
|
|
HSF1
|
heat shock transcription factor 1
|
-2.6725
|
|
THEM6
|
thioesterase superfamily member 6
|
-2.63773
|
|
TLK2
|
tousled-like kinase 2
|
-2.56218
|
|
BOP1
|
block of proliferation 1
|
-2.5029
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.47904
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.46793
|
|
ZNF7
|
zinc finger protein 7
|
-2.43362
|
|
CPSF1
|
cleavage and polyadenylation specific factor 1, 160kDa
|
-2.34346
|
|
PRAME
|
preferentially expressed antigen in melanoma
|
-2.18508
|
|
GCG
|
glucagon
|
-2.1326
|
|
LOC128031832
|
uncharacterized LOC128031832
|
-2.08112
|
|
HPS4
|
Hermansky-Pudlak syndrome 4
|
-2.04479
|
|
ZFTRAF1
|
zinc finger TRAF-type containing 1
|
-2.0251
|
|
ZC3H3
|
zinc finger CCCH-type containing 3
|
-2.01814
|
|
EHBP1L1
|
EH domain binding protein 1-like 1
|
-2.01013
|