CRCGN017_MCF10A.TP53.M_24H:C18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrolein 11.44 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.32939
ZNF134 zinc finger protein 134 3.39298
ZNF586 zinc finger protein 586 3.37582
ACAA1 acetyl-CoA acyltransferase 1 2.98497
ZNF211 zinc finger protein 211 2.94835
TOMM34 translocase of outer mitochondrial membrane 34 2.85938
CNRIP1 cannabinoid receptor interacting protein 1 2.71566
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.60834
CCNA1 cyclin A1 2.58827
GATA3 GATA binding protein 3 2.58428
ZNF329 zinc finger protein 329 2.49934
ZNF304 zinc finger protein 304 2.43346
NOSIP nitric oxide synthase interacting protein 2.41182
ZNF419 zinc finger protein 419 2.12264
COMP cartilage oligomeric matrix protein 2.104
BMP4 bone morphogenetic protein 4 2.06144
RBP4 retinol binding protein 4, plasma 2.05754

decreased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 -4.35811
HMG20B high mobility group 20B -3.98119
CD44 CD44 molecule (Indian blood group) -2.95635
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.64512
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.45725
KDM3A lysine (K)-specific demethylase 3A -2.05074