CRCGN017_MCF10A.TP53.M_24H:C21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mitoxantrone 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

917 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:C21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TICAM1 toll-like receptor adaptor molecule 1 6.34651
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.27634
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 5.16663
TERF2IP telomeric repeat binding factor 2, interacting protein 5.13774
PDGFA platelet-derived growth factor alpha polypeptide 5.11306
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 5.07481
MCOLN1 mucolipin 1 4.99654
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.73487
SNIP1 Smad nuclear interacting protein 1 4.6534
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.51195
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 4.50494
RBKS ribokinase 4.48858
DUSP14 dual specificity phosphatase 14 4.4529
STAT1 signal transducer and activator of transcription 1, 91kDa 4.44815
PLA2G15 phospholipase A2, group XV 4.44497
SAMD9 sterile alpha motif domain containing 9 4.43912
ATF5 activating transcription factor 5 4.33743
KLHL21 kelch-like family member 21 4.28682
TRIB1 tribbles pseudokinase 1 4.11652
CHIC2 cysteine-rich hydrophobic domain 2 3.97135
TBPL1 TBP-like 1 3.95611
TXLNA taxilin alpha 3.92311
NGRN neugrin, neurite outgrowth associated 3.88185
ISG15 ISG15 ubiquitin-like modifier 3.86237
RMC1 regulator of MON1-CCZ1 3.8363
OASL 2'-5'-oligoadenylate synthetase-like 3.81208
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 3.80629
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.77807
TMEM50A transmembrane protein 50A 3.76831
TIMP2 TIMP metallopeptidase inhibitor 2 3.76489
RNF25 ring finger protein 25 3.75885
CCNE2 cyclin E2 3.74747
TLR4 toll-like receptor 4 3.71185
ASTE1 asteroid homolog 1 (Drosophila) 3.68483
ZNF14 zinc finger protein 14 3.67518
ATF3 activating transcription factor 3 3.66415
IGFBP3 insulin-like growth factor binding protein 3 3.63415
MIS12 MIS12 kinetochore complex component 3.61272
TRIM21 tripartite motif containing 21 3.60158
MEA1 male-enhanced antigen 1 3.58611
SKIC2 SKI2 subunit of superkiller complex 3.5475
MISP mitotic spindle positioning 3.54586
FOXO4 forkhead box O4 3.51939
FHL2 four and a half LIM domains 2 3.5065
TRNAU1AP tRNA selenocysteine 1 associated protein 1 3.50608
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 3.49995
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 3.48276
IP6K2 inositol hexakisphosphate kinase 2 3.45917
CCL3L3 chemokine (C-C motif) ligand 3-like 3 3.44182
ALAS1 5'-aminolevulinate synthase 1 3.43727
APOL6 apolipoprotein L, 6 3.42747
IFI27 interferon, alpha-inducible protein 27 3.42396
IRF7 interferon regulatory factor 7 3.41792
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 3.41127
JOSD1 Josephin domain containing 1 3.40611
FURIN furin (paired basic amino acid cleaving enzyme) 3.40558
TSPAN6 tetraspanin 6 3.3722
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.37156
YIPF1 Yip1 domain family, member 1 3.36297
CDPF1 cysteine-rich, DPF motif domain containing 1 3.34664
APOL2 apolipoprotein L, 2 3.33237
MBD1 methyl-CpG binding domain protein 1 3.32822
GADD45B growth arrest and DNA-damage-inducible, beta 3.28237
MUC1 mucin 1, cell surface associated 3.28079
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 3.27764
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 3.26342
LGMN legumain 3.23832
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 3.2382
IER5 immediate early response 5 3.23528
IRF9 interferon regulatory factor 9 3.23053
UBE2A ubiquitin-conjugating enzyme E2A 3.22367
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.21836
CCL23 chemokine (C-C motif) ligand 23 3.21576
TMEM59 transmembrane protein 59 3.21119
CSRNP2 cysteine-serine-rich nuclear protein 2 3.19793
MAPK7 mitogen-activated protein kinase 7 3.18721
CDKN2AIP CDKN2A interacting protein 3.17444
BECN1 beclin 1, autophagy related 3.17409
SLC25A44 solute carrier family 25, member 44 3.17097
CXADR coxsackie virus and adenovirus receptor 3.16549
LIN37 lin-37 DREAM MuvB core complex component 3.16268
CEMIP2 cell migration inducing hyaluronidase 2 3.15333
GOLT1B golgi transport 1B 3.14925
MTCH1 mitochondrial carrier 1 3.14621
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.14333
MAP6D1 MAP6 domain containing 1 3.13944
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 3.12835
PSMC3IP PSMC3 interacting protein 3.10713
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.08512
SPATA2L spermatogenesis associated 2-like 3.08414
FEN1 flap structure-specific endonuclease 1 3.08034
GATA2 GATA binding protein 2 3.07996
TUBB6 tubulin, beta 6 class V 3.0753
CCNE1 cyclin E1 3.07199
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 3.06847
SDF2 stromal cell-derived factor 2 3.06498
AIRIM AFG2 interacting ribosome maturation factor 3.06091
CLDN1 claudin 1 3.03538
DERL2 derlin 2 3.03114
HSPB11 heat shock protein family B (small), member 11 3.02531
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 3.02007
IRF1 interferon regulatory factor 1 2.98617
ERCC3 excision repair cross-complementation group 3 2.97519
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.96673
IFI6 interferon, alpha-inducible protein 6 2.94085
ALDOC aldolase C, fructose-bisphosphate 2.92873
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.92276
DDA1 DET1 and DDB1 associated 1 2.92206
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 2.91429
NPFFR1 neuropeptide FF receptor 1 2.91311
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.89926
ZNF232 zinc finger protein 232 2.89455
GTF2B general transcription factor IIB 2.89419
LHB luteinizing hormone beta polypeptide 2.88459
FASTKD5 FAST kinase domains 5 2.88227
CLEC4M C-type lectin domain family 4, member M 2.88147
NCSTN nicastrin 2.87479
MOCS3 molybdenum cofactor synthesis 3 2.87077
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.86718
ARAF A-Raf proto-oncogene, serine/threonine kinase 2.84621
GAA glucosidase, alpha; acid 2.84233
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.82991
CCNJ cyclin J 2.82749
CAPN1 calpain 1, (mu/I) large subunit 2.81524
IFI44L interferon-induced protein 44-like 2.79944
MAMLD1 mastermind-like domain containing 1 2.79832
CNRIP1 cannabinoid receptor interacting protein 1 2.79793
H2BC12 H2B clustered histone 12 2.79346
RNF103 ring finger protein 103 2.79119
DNAH17 dynein, axonemal, heavy chain 17 2.7896
CANT1 calcium activated nucleotidase 1 2.78948
MON1B MON1 secretory trafficking family member B 2.78629
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.78182
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.76455
IFI44 interferon-induced protein 44 2.76261
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.76182
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.75971
KLK1 kallikrein 1 2.75518
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.75012
CCDC92 coiled-coil domain containing 92 2.74641
TRIM45 tripartite motif containing 45 2.74431
MAD2L1BP MAD2L1 binding protein 2.74069
AUP1 ancient ubiquitous protein 1 2.73515
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.7281
POU4F2 POU class 4 homeobox 2 2.72347
INPP5K inositol polyphosphate-5-phosphatase K 2.7231
TIMELESS timeless circadian clock 2.72272
IL23A interleukin 23, alpha subunit p19 2.71996
DAZL deleted in azoospermia-like 2.71976
GDI1 GDP dissociation inhibitor 1 2.70384
ZNF432 zinc finger protein 432 2.70087
TNF tumor necrosis factor 2.69922
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 2.69898
IL22RA1 interleukin 22 receptor, alpha 1 2.69444
KDM6B lysine (K)-specific demethylase 6B 2.69415
TOR1B torsin family 1, member B (torsin B) 2.6873
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.67984
IL36G interleukin 36, gamma 2.67895
LZTS3 leucine zipper, putative tumor suppressor family member 3 2.67654
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.67156
IFIH1 interferon induced with helicase C domain 1 2.66963
FKRP fukutin related protein 2.66879
ETV7 ets variant 7 2.66649
CCDC93 coiled-coil domain containing 93 2.66503
SMG8 SMG8 nonsense mediated mRNA decay factor 2.66335
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2.6633
S100A13 S100 calcium binding protein A13 2.66153
RECQL RecQ helicase-like 2.65481
USP36 ubiquitin specific peptidase 36 2.6531
SAP30L SAP30-like 2.64988
ZNF646 zinc finger protein 646 2.64981
F8A2 coagulation factor VIII-associated 2 2.64869
EOLA1 endothelium and lymphocyte associated ASCH domain 1 2.64786
PPT1 palmitoyl-protein thioesterase 1 2.64645
ICAM1 intercellular adhesion molecule 1 2.64344
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.64246
FMNL1 formin-like 1 2.63129
SETD1A SET domain containing 1A 2.61898
DEFB126 defensin, beta 126 2.61796
SHFL shiftless antiviral inhibitor of ribosomal frameshifting 2.61736
KRT34 keratin 34, type I 2.61428
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.61337
ASB1 ankyrin repeat and SOCS box containing 1 2.61131
TUFT1 tuftelin 1 2.60841
DOHH deoxyhypusine hydroxylase/monooxygenase 2.60568
ELSPBP1 epididymal sperm binding protein 1 2.58802
BTG3 BTG family, member 3 2.58664
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.57622
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.56551
GPATCH3 G patch domain containing 3 2.56514
CCP110 centriolar coiled coil protein 110kDa 2.56293
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.56028
EIF5A2 eukaryotic translation initiation factor 5A2 2.55977
HTN3 histatin 3 2.54961
FZD7 frizzled class receptor 7 2.54874
KLHL25 kelch-like family member 25 2.54542
PI3 peptidase inhibitor 3, skin-derived 2.544
NRBF2 nuclear receptor binding factor 2 2.54314
MARCKS myristoylated alanine-rich protein kinase C substrate 2.54257
DRC3 dynein regulatory complex subunit 3 2.54101
CCL4 chemokine (C-C motif) ligand 4 2.54057
GNLY granulysin 2.53939
CRIPT cysteine-rich PDZ-binding protein 2.53494
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.53359
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.53037
STMN1 stathmin 1 2.52802
TLR7 toll-like receptor 7 2.5266
PMP22 peripheral myelin protein 22 2.52351
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 2.52045
MUC13 mucin 13, cell surface associated 2.51873
LCAT lecithin-cholesterol acyltransferase 2.51309
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.51293
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.50243
DSCC1 DNA replication and sister chromatid cohesion 1 2.50188
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.50034
TEX14 testis expressed 14 2.4989
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.49413
KLF10 Kruppel-like factor 10 2.49167
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.49103
RSAD2 radical S-adenosyl methionine domain containing 2 2.48672
TYK2 tyrosine kinase 2 2.48177
H2AB2 H2A.B variant histone 2 2.48165
USB1 U6 snRNA biogenesis 1 2.48062
FAM53C family with sequence similarity 53, member C 2.47644
ADAP1 ArfGAP with dual PH domains 1 2.47534
ARID5A AT rich interactive domain 5A (MRF1-like) 2.47334
TMEM140 transmembrane protein 140 2.46693
TTI1 TELO2 interacting protein 1 2.46649
RAD51AP1 RAD51 associated protein 1 2.46318
APOL1 apolipoprotein L, 1 2.46291
PEPD peptidase D 2.46193
DSN1 DSN1, MIS12 kinetochore complex component 2.45996
EGR4 early growth response 4 2.45968
PILRA paired immunoglobin-like type 2 receptor alpha 2.45888
DOK2 docking protein 2, 56kDa 2.45683
PADI2 peptidyl arginine deiminase, type II 2.44461
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.44312
GUSB glucuronidase, beta 2.44227
TUBB2A tubulin, beta 2A class IIa 2.43959
BCOR BCL6 corepressor 2.4383
BSDC1 BSD domain containing 1 2.43799
MARCKSL1 MARCKS-like 1 2.43384
E2F8 E2F transcription factor 8 2.43105
CHUK conserved helix-loop-helix ubiquitous kinase 2.42962
RBM22 RNA binding motif protein 22 2.42593
RTP4 receptor (chemosensory) transporter protein 4 2.41977
TUBB4B tubulin, beta 4B class IVb 2.41897
MAN2A2 mannosidase, alpha, class 2A, member 2 2.41259
KLHL26 kelch-like family member 26 2.40828
FBXL12 F-box and leucine-rich repeat protein 12 2.4076
TOE1 target of EGR1, member 1 (nuclear) 2.40667
G6PC2 glucose-6-phosphatase, catalytic, 2 2.4061
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.40568
ZFP36 ZFP36 ring finger protein 2.40378
IL1B interleukin 1, beta 2.40302
TKTL1 transketolase-like 1 2.40108
MAGEA9B melanoma antigen family A9B 2.3998
IL2RB interleukin 2 receptor, beta 2.39598
PPME1 protein phosphatase methylesterase 1 2.39245
SIRT1 sirtuin 1 2.38642
CARD9 caspase recruitment domain family, member 9 2.3851
NDRG1 N-myc downstream regulated 1 2.38171
ZNF79 zinc finger protein 79 2.38156
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 2.3813
NPTX1 neuronal pentraxin I 2.38032
SMIM10L1 small integral membrane protein 10 like 1 2.38028
KLF4 Kruppel-like factor 4 (gut) 2.37892
SHARPIN SHANK-associated RH domain interactor 2.37816
CD37 CD37 molecule 2.37395
GNAS GNAS complex locus 2.37085
GMPPA GDP-mannose pyrophosphorylase A 2.36825
RAB4B RAB4B, member RAS oncogene family 2.36697
TCHH trichohyalin 2.3662
GPATCH1 G patch domain containing 1 2.3634
KLF11 Kruppel-like factor 11 2.36087
PLAUR plasminogen activator, urokinase receptor 2.35546
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.35491
GALNS galactosamine (N-acetyl)-6-sulfatase 2.3548
ATG13 autophagy related 13 2.34928
ATG2A autophagy related 2A 2.34873
RNF186 ring finger protein 186 2.34438
IL12RB2 interleukin 12 receptor, beta 2 2.33964
COL9A2 collagen, type IX, alpha 2 2.33833
SLC38A3 solute carrier family 38, member 3 2.33764
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.33727
PEG10 paternally expressed 10 2.33587
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.33431
RFC4 replication factor C (activator 1) 4, 37kDa 2.33176
APOL3 apolipoprotein L, 3 2.32956
FAM3A family with sequence similarity 3, member A 2.31648
MX1 MX dynamin-like GTPase 1 2.31593
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.31323
TRIM62 tripartite motif containing 62 2.31248
KIF1A kinesin family member 1A 2.31166
TCN2 transcobalamin II 2.31001
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 2.30843
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.30572
ADGRD2 adhesion G protein-coupled receptor D2 2.30504
CCDC71 coiled-coil domain containing 71 2.30462
KRT85 keratin 85, type II 2.30438
PDIA2 protein disulfide isomerase family A, member 2 2.30386
SLAMF1 signaling lymphocytic activation molecule family member 1 2.30362
PIPOX pipecolic acid oxidase 2.30003
RBL1 retinoblastoma-like 1 2.29989
NPR1 natriuretic peptide receptor 1 2.29731
CCL20 chemokine (C-C motif) ligand 20 2.29627
HAO2 hydroxyacid oxidase 2 (long chain) 2.29495
PINK1 PTEN induced putative kinase 1 2.29448
WRNIP1 Werner helicase interacting protein 1 2.29241
EIF1B eukaryotic translation initiation factor 1B 2.29051
TUBB2B tubulin, beta 2B class IIb 2.28866
YIPF3 Yip1 domain family, member 3 2.28783
PTPRR protein tyrosine phosphatase, receptor type, R 2.28721
ADAM7 ADAM metallopeptidase domain 7 2.28482
THAP10 THAP domain containing 10 2.28481
VCX3A variable charge, X-linked 3A 2.28339
PCDHGA11 protocadherin gamma subfamily A, 11 2.28023
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.28007
GPX4 glutathione peroxidase 4 2.27956
GPR137B G protein-coupled receptor 137B 2.27886
RFWD3 ring finger and WD repeat domain 3 2.27791
CDC6 cell division cycle 6 2.27679
HOXD1 homeobox D1 2.27668
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.27405
AGRP agouti related neuropeptide 2.274
TTI2 TELO2 interacting protein 2 2.27327
CCN3 cellular communication network factor 3 2.27261
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 2.27193
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.27104
ULBP2 UL16 binding protein 2 2.26871
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.26838
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.26789
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.26766
CALCOCO1 calcium binding and coiled-coil domain 1 2.26508
SERF1A small EDRK-rich factor 1A (telomeric) 2.26324
SSR4 signal sequence receptor, delta 2.26199
SARAF store-operated calcium entry-associated regulatory factor 2.2617
CYBRD1 cytochrome b reductase 1 2.25899
SLBP stem-loop binding protein 2.25722
MED9 mediator complex subunit 9 2.25689
CDC25A cell division cycle 25A 2.25613
RBM48 RNA binding motif protein 48 2.25436
SOX4 SRY (sex determining region Y)-box 4 2.25387
PRSS22 protease, serine, 22 2.25323
RUSC2 RUN and SH3 domain containing 2 2.25231
LSR lipolysis stimulated lipoprotein receptor 2.25148
GPR153 G protein-coupled receptor 153 2.25095
CCL15 chemokine (C-C motif) ligand 15 2.25077
DUSP10 dual specificity phosphatase 10 2.24832
KEAP1 kelch-like ECH-associated protein 1 2.24487
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 2.2441
ZNF45 zinc finger protein 45 2.24085
CCR9 chemokine (C-C motif) receptor 9 2.24007
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.23991
PRAF2 PRA1 domain family, member 2 2.23921
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.2392
ANKRD37 ankyrin repeat domain 37 2.23375
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.23339
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.23224
KRT17 keratin 17, type I 2.23133
PWWP3A PWWP domain containing 3A, DNA repair factor 2.23101
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.22914
USP18 ubiquitin specific peptidase 18 2.22697
MYL9 myosin, light chain 9, regulatory 2.22615
LAMP3 lysosomal-associated membrane protein 3 2.22554
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.22434
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.22333
TBC1D31 TBC1 domain family, member 31 2.22179
BRME1 break repair meiotic recombinase recruitment factor 1 2.21991
ESRP2 epithelial splicing regulatory protein 2 2.2193
HOXB5 homeobox B5 2.21494
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.21464
ADA2 adenosine deaminase 2 2.21414
PICK1 protein interacting with PRKCA 1 2.21351
ZNF536 zinc finger protein 536 2.21316
PROX1 prospero homeobox 1 2.21236
CD4 CD4 molecule 2.21121
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 2.21048
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.20998
SLC35B1 solute carrier family 35, member B1 2.20865
RBP4 retinol binding protein 4, plasma 2.20745
CALB1 calbindin 1, 28kDa 2.20435
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.20263
CPTP ceramide-1-phosphate transfer protein 2.20246
SUGP1 SURP and G patch domain containing 1 2.20141
LMTK1 lemur tail kinase 1 2.2008
ZNF222 zinc finger protein 222 2.20015
ZNF180 zinc finger protein 180 2.19923
PLAAT4 phospholipase A and acyltransferase 4 2.19668
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.19602
GP9 glycoprotein IX (platelet) 2.19548
TPM1 tropomyosin 1 (alpha) 2.19539
TOMM34 translocase of outer mitochondrial membrane 34 2.19419
MRM2 mitochondrial rRNA methyltransferase 2 2.19249
ACTL6A actin-like 6A 2.19228
EXO5 exonuclease 5 2.19124
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 2.19087
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.19036
OXCT2 3-oxoacid CoA transferase 2 2.19032
ADORA3 adenosine A3 receptor 2.18939
GPR19 G protein-coupled receptor 19 2.18722
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 2.18494
GRN granulin 2.181
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.17983
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.17935
ADAM8 ADAM metallopeptidase domain 8 2.17653
CTAG2 cancer/testis antigen 2 2.17539
PDCD1LG2 programmed cell death 1 ligand 2 2.17231
NAP1L3 nucleosome assembly protein 1-like 3 2.17177
BLZF1 basic leucine zipper nuclear factor 1 2.17062
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.16924
LOC114841035 uncharacterized LOC114841035 2.16897
PGK2 phosphoglycerate kinase 2 2.16831
FANCI Fanconi anemia, complementation group I 2.16773
FBXO46 F-box protein 46 2.1671
RTL8A retrotransposon Gag like 8A 2.16478
STBD1 starch binding domain 1 2.16318
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.15961
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.15859
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.15815
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.15716
FAM110D family with sequence similarity 110, member D 2.15697
CNGA3 cyclic nucleotide gated channel alpha 3 2.15617
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.15534
CRYBB1 crystallin, beta B1 2.15442
SH2D2A SH2 domain containing 2A 2.15351
SLC35G2 solute carrier family 35, member G2 2.1533
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 2.153
CMKLR1 chemerin chemokine-like receptor 1 2.15295
EYA2 EYA transcriptional coactivator and phosphatase 2 2.15253
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.15217
DRC9 dynein regulatory complex subunit 9 2.15129
PARP12 poly (ADP-ribose) polymerase family, member 12 2.14914
HOXD11 homeobox D11 2.14808
GMEB2 glucocorticoid modulatory element binding protein 2 2.14376
ACHE acetylcholinesterase (Yt blood group) 2.14284
TSGA10 testis specific, 10 2.13957
ALK anaplastic lymphoma receptor tyrosine kinase 2.13849
TJAP1 tight junction associated protein 1 (peripheral) 2.13845
ITPRID2 ITPR interacting domain containing 2 2.13806
RING1 ring finger protein 1 2.13497
CDK2 cyclin-dependent kinase 2 2.13369
SNF8 SNF8, ESCRT-II complex subunit 2.13207
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.1312
NT5M 5',3'-nucleotidase, mitochondrial 2.13081
BGLAP bone gamma-carboxyglutamate (gla) protein 2.13005
TOB1 transducer of ERBB2, 1 2.12972
ABHD4 abhydrolase domain containing 4 2.12944
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough 2.12909
DKK2 dickkopf WNT signaling pathway inhibitor 2 2.12898
CCL5 chemokine (C-C motif) ligand 5 2.12867
CDK11A cyclin-dependent kinase 11A 2.12809
SSTR3 somatostatin receptor 3 2.12466
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.12198
DUSP8 dual specificity phosphatase 8 2.12088
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 2.11927
EFNB1 ephrin-B1 2.11857
TMSB4Y thymosin beta 4, Y-linked 2.11846
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.11762
LMO7 LIM domain 7 2.11467
ARMCX6 armadillo repeat containing, X-linked 6 2.11455
VCPKMT valosin containing protein lysine (K) methyltransferase 2.11346
RNF11 ring finger protein 11 2.11111
ADAR adenosine deaminase, RNA-specific 2.11107
SPINK1 serine peptidase inhibitor, Kazal type 1 2.11094
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 2.1105
DDB2 damage-specific DNA binding protein 2, 48kDa 2.10999
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2.10914
CYB5R3 cytochrome b5 reductase 3 2.10886
TMEM106C transmembrane protein 106C 2.10852
ZBP1 Z-DNA binding protein 1 2.10799
C6ORF89 chromosome 6 open reading frame 89 2.10618
SPAG1 sperm associated antigen 1 2.1044
CCDC33 coiled-coil domain containing 33 2.10355
TMED1 transmembrane emp24 protein transport domain containing 1 2.09971
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.09831
MOAP1 modulator of apoptosis 1 2.09572
TLR8 toll-like receptor 8 2.09565
NHLH1 nescient helix loop helix 1 2.09367
ATRIP ATR interacting protein 2.09336
NAPSA napsin A aspartic peptidase 2.09121
CCN2 cellular communication network factor 2 2.08951
DNAI4 dynein axonemal intermediate chain 4 2.08911
SCAMP2 secretory carrier membrane protein 2 2.08891
GINS3 GINS complex subunit 3 (Psf3 homolog) 2.08769
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.08581
NACAD NAC alpha domain containing 2.08529
LMNA lamin A/C 2.08419
ALOX5 arachidonate 5-lipoxygenase 2.08344
PCDHA10 protocadherin alpha 10 2.08211
DLX2 distal-less homeobox 2 2.08071
RYR1 ryanodine receptor 1 (skeletal) 2.08038
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.0795
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 2.0789
CHMP1B charged multivesicular body protein 1B 2.07776
RIGI RNA sensor RIG-I 2.07702
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 2.07573
BBS4 Bardet-Biedl syndrome 4 2.07494
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 2.07378
IZUMO4 IZUMO family member 4 2.07188
TRIM13 tripartite motif containing 13 2.06774
CPT2 carnitine palmitoyltransferase 2 2.06687
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 2.06511
MSLN mesothelin 2.06477
INAVA innate immunity activator 2.06299
RNF122 ring finger protein 122 2.06119
LTA lymphotoxin alpha 2.06104
CXXC4 CXXC finger protein 4 2.06047
MRPL33 mitochondrial ribosomal protein L33 2.05972
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.0594
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.05743
CYSLTR2 cysteinyl leukotriene receptor 2 2.05457
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 2.05341
SRSF11 serine/arginine-rich splicing factor 11 2.05324
EXOSC10 exosome component 10 2.05238
TP53BP2 tumor protein p53 binding protein 2 2.05103
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.05004
STAMBP STAM binding protein 2.0499
BCAS1 breast carcinoma amplified sequence 1 2.04807
STXBP2 syntaxin binding protein 2 2.04502
CEMIP cell migration inducing protein, hyaluronan binding 2.04405
MYD88 myeloid differentiation primary response 88 2.04267
SAP30BP SAP30 binding protein 2.04133
SAFB2 scaffold attachment factor B2 2.03743
IRGQ immunity-related GTPase family, Q 2.03737
KRT75 keratin 75, type II 2.03721
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.03709
NECTIN3 nectin cell adhesion molecule 3 2.03652
GAS2 growth arrest-specific 2 2.03473
SUCO SUN domain containing ossification factor 2.03388
TMEM45A transmembrane protein 45A 2.03253
SYNC syncoilin, intermediate filament protein 2.03188
PLAC1 placenta-specific 1 2.03167
EMC6 ER membrane protein complex subunit 6 2.03009
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.02955
TMEM184C transmembrane protein 184C 2.02932
YIPF4 Yip1 domain family, member 4 2.02922
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.02816
HTN1 histatin 1 2.02762
RLN2 relaxin 2 2.02654
ZNF529 zinc finger protein 529 2.02632
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.0261
FGF1 fibroblast growth factor 1 (acidic) 2.02609
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 2.0247
MARCHF2 membrane associated ring-CH-type finger 2 2.02353
PNPLA2 patatin-like phospholipase domain containing 2 2.0224
SAC3D1 SAC3 domain containing 1 2.02061
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.02002
LRP10 low density lipoprotein receptor-related protein 10 2.01964
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.01928
INKA2 inka box actin regulator 2 2.01685
CIC capicua transcriptional repressor 2.01681
FASLG Fas ligand (TNF superfamily, member 6) 2.01535
BLCAP bladder cancer associated protein 2.01456
JAM2 junctional adhesion molecule 2 2.01391
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.01319
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.01251
CDC45 cell division cycle 45 2.01176
ZBTB39 zinc finger and BTB domain containing 39 2.00991
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 2.00583
TCF15 transcription factor 15 (basic helix-loop-helix) 2.00579
CLIC5 chloride intracellular channel 5 2.00137
IL2RG interleukin 2 receptor, gamma 2.00111
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.00061

decreased expression

Symbol Name Standardized Value
DDIT4 DNA-damage-inducible transcript 4 -10.0
ASCC3 activating signal cointegrator 1 complex subunit 3 -8.16022
CRTAP cartilage associated protein -7.04384
TM9SF3 transmembrane 9 superfamily member 3 -5.73292
LBR lamin B receptor -5.10089
MNAT1 MNAT CDK-activating kinase assembly factor 1 -5.00955
BZW2 basic leucine zipper and W2 domains 2 -4.97953
UBE3C ubiquitin protein ligase E3C -4.79449
NCK2 NCK adaptor protein 2 -4.62887
PSRC1 proline/serine-rich coiled-coil 1 -4.52122
RBM6 RNA binding motif protein 6 -4.42842
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -4.35694
ECD ecdysoneless homolog (Drosophila) -4.32616
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -4.21975
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -4.01815
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.00275
CPNE3 copine III -3.99158
SQOR sulfide quinone oxidoreductase -3.98755
IARS1 isoleucyl-tRNA synthetase 1 -3.97953
DNM1L dynamin 1-like -3.94016
TAC4 tachykinin 4 (hemokinin) -3.93988
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.89281
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -3.87761
PGM1 phosphoglucomutase 1 -3.76295
TKT transketolase -3.73844
GPHN gephyrin -3.73422
WAPL WAPL cohesin release factor -3.73176
MRPL12 mitochondrial ribosomal protein L12 -3.69929
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -3.64968
TEX10 testis expressed 10 -3.64919
THAP11 THAP domain containing 11 -3.63251
MPZL1 myelin protein zero-like 1 -3.62544
CUL1 cullin 1 -3.58161
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -3.51979
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.50844
PLK1 polo-like kinase 1 -3.49488
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -3.47733
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -3.44733
RHOT1 ras homolog family member T1 -3.4412
SETD5 SET domain containing 5 -3.43007
BACE2 beta-site APP-cleaving enzyme 2 -3.40455
EXOC2 exocyst complex component 2 -3.39065
GPD1L glycerol-3-phosphate dehydrogenase 1-like -3.37226
CLNS1A chloride channel, nucleotide-sensitive, 1A -3.31909
TCERG1 transcription elongation regulator 1 -3.31028
MRPS27 mitochondrial ribosomal protein S27 -3.27857
CDC20 cell division cycle 20 -3.25545
EIF3E eukaryotic translation initiation factor 3, subunit E -3.24868
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -3.2114
ANAPC1 anaphase promoting complex subunit 1 -3.19747
ITGA10 integrin, alpha 10 -3.18246
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.18204
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -3.15537
SCARB1 scavenger receptor class B, member 1 -3.1548
RUVBL1 RuvB-like AAA ATPase 1 -3.14352
NUP43 nucleoporin 43kDa -3.12951
TLK2 tousled-like kinase 2 -3.1294
NUP37 nucleoporin 37kDa -3.12926
CCNC cyclin C -3.10873
TMEM109 transmembrane protein 109 -3.10423
SCMH1 sex comb on midleg homolog 1 (Drosophila) -3.1025
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -3.10249
EIF2D eukaryotic translation initiation factor 2D -3.10242
TULP4 tubby like protein 4 -3.09871
TSC22D3 TSC22 domain family, member 3 -3.09743
SUMF2 sulfatase modifying factor 2 -3.08206
MTREX Mtr4 exosome RNA helicase -3.069
PRKX protein kinase, X-linked -3.04594
GPSM2 G-protein signaling modulator 2 -3.03631
METRN meteorin, glial cell differentiation regulator -3.03041
RBM28 RNA binding motif protein 28 -3.02742
PPA1 pyrophosphatase (inorganic) 1 -3.02122
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.00772
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.99377
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.93994
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -2.93308
CD58 CD58 molecule -2.92836
DCTD dCMP deaminase -2.92494
RAD50 RAD50 homolog (S. cerevisiae) -2.91083
C2CD2 C2 calcium-dependent domain containing 2 -2.90955
ANXA7 annexin A7 -2.89625
ELP4 elongator acetyltransferase complex subunit 4 -2.89252
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.88756
TFB1M transcription factor B1, mitochondrial -2.88528
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -2.88478
PUS1 pseudouridylate synthase 1 -2.87588
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.87506
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.87416
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.86283
IPO7 importin 7 -2.86174
FAF1 Fas (TNFRSF6) associated factor 1 -2.83741
ELOVL6 ELOVL fatty acid elongase 6 -2.83514
INTS8 integrator complex subunit 8 -2.8266
PDS5A PDS5 cohesin associated factor A -2.82577
CCNB2 cyclin B2 -2.81579
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.80302
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.80098
RPIA ribose 5-phosphate isomerase A -2.80091
PUM2 pumilio RNA-binding family member 2 -2.79307
KANK1 KN motif and ankyrin repeat domains 1 -2.76584
ZFAND1 zinc finger, AN1-type domain 1 -2.75748
NAT10 N-acetyltransferase 10 (GCN5-related) -2.75441
RAD23B RAD23 homolog B (S. cerevisiae) -2.74301
UIMC1 ubiquitin interaction motif containing 1 -2.73892
MRPL42 mitochondrial ribosomal protein L42 -2.73587
UFSP2 UFM1-specific peptidase 2 -2.72962
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.72962
NCAPD2 non-SMC condensin I complex, subunit D2 -2.7277
TUBGCP4 tubulin, gamma complex associated protein 4 -2.71693
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -2.70392
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.70046
NIT2 nitrilase family, member 2 -2.69919
BLVRA biliverdin reductase A -2.69319
WDR41 WD repeat domain 41 -2.68985
OAT ornithine aminotransferase -2.68326
LPP LIM domain containing preferred translocation partner in lipoma -2.68092
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.68046
CAB39 calcium binding protein 39 -2.66696
AARS1 alanyl-tRNA synthetase 1 -2.66452
PYCR1 pyrroline-5-carboxylate reductase 1 -2.65183
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -2.65051
RBMX RNA binding motif protein, X-linked -2.649
PIBF1 progesterone immunomodulatory binding factor 1 -2.63632
C1QBP complement component 1, q subcomponent binding protein -2.62935
VRK2 vaccinia related kinase 2 -2.62202
TBC1D5 TBC1 domain family, member 5 -2.60804
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -2.60086
PROCR protein C receptor, endothelial -2.60007
NSD1 nuclear receptor binding SET domain protein 1 -2.59696
MSRA methionine sulfoxide reductase A -2.59179
CLTC clathrin, heavy chain (Hc) -2.5854
EPHB2 EPH receptor B2 -2.5845
TSKU tsukushi, small leucine rich proteoglycan -2.58259
KIAA0586 KIAA0586 -2.58175
BLMH bleomycin hydrolase -2.58109
SKIC3 SKI3 subunit of superkiller complex -2.58049
MRPL58 mitochondrial ribosomal protein L58 -2.57876
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.5778
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -2.57676
DERA deoxyribose-phosphate aldolase (putative) -2.57638
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.57537
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.57195
HMGN4 high mobility group nucleosomal binding domain 4 -2.56749
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.56486
GOLGA4 golgin A4 -2.54654
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.54451
SLK STE20-like kinase -2.54287
CDK6 cyclin-dependent kinase 6 -2.54268
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.53938
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -2.53614
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.53425
IDE insulin-degrading enzyme -2.53373
SLC35F2 solute carrier family 35, member F2 -2.52595
PARN poly(A)-specific ribonuclease -2.52175
PUS7 pseudouridylate synthase 7 (putative) -2.51596
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.51325
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.51257
CDK7 cyclin-dependent kinase 7 -2.51227
NHP2 NHP2 ribonucleoprotein -2.51063
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.50537
BRD7 bromodomain containing 7 -2.49551
KIF14 kinesin family member 14 -2.49366
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.49224
RBL2 retinoblastoma-like 2 -2.48342
COMMD10 COMM domain containing 10 -2.482
ZMIZ1 zinc finger, MIZ-type containing 1 -2.47667
EP400 E1A binding protein p400 -2.46919
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.45325
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.44304
XPOT exportin, tRNA -2.44027
LARS1 leucyl-tRNA synthetase 1 -2.43853
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.4373
MEMO1 mediator of cell motility 1 -2.43692
CUTC cutC copper transporter -2.43322
TRIB3 tribbles pseudokinase 3 -2.43246
MRPS35 mitochondrial ribosomal protein S35 -2.42781
MDN1 MDN1, midasin homolog (yeast) -2.42
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -2.4171
HEATR1 HEAT repeat containing 1 -2.4164
PHACTR2 phosphatase and actin regulator 2 -2.41323
FKBP5 FK506 binding protein 5 -2.40834
CHD9 chromodomain helicase DNA binding protein 9 -2.4012
MAP7 microtubule-associated protein 7 -2.39479
TRIM27 tripartite motif containing 27 -2.39216
PCDHB11 protocadherin beta 11 -2.3912
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.38637
FBL fibrillarin -2.38631
TOP2B topoisomerase (DNA) II beta 180kDa -2.38325
ITGA6 integrin, alpha 6 -2.37906
TMEM168 transmembrane protein 168 -2.37591
AMDHD2 amidohydrolase domain containing 2 -2.36871
ATP5PO ATP synthase peripheral stalk subunit OSCP -2.36704
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -2.36648
TBCA tubulin folding cofactor A -2.36227
APIP APAF1 interacting protein -2.35597
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.35581
PTK2 protein tyrosine kinase 2 -2.35395
MED28 mediator complex subunit 28 -2.353
JAK1 Janus kinase 1 -2.35282
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.35244
NCOA3 nuclear receptor coactivator 3 -2.35133
TOMM70 translocase of outer mitochondrial membrane 70 -2.35111
EFR3A EFR3 homolog A (S. cerevisiae) -2.34872
SNUPN snurportin 1 -2.34856
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.3406
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.33434
NPM3 nucleophosmin/nucleoplasmin 3 -2.33327
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -2.32765
MTDH metadherin -2.32156
PHKB phosphorylase kinase, beta -2.31533
ARHGAP10 Rho GTPase activating protein 10 -2.31507
CLOCK clock circadian regulator -2.31069
NTHL1 nth endonuclease III-like 1 (E. coli) -2.30695
MTFR1 mitochondrial fission regulator 1 -2.30369
FAM216A family with sequence similarity 216, member A -2.30246
NGLY1 N-glycanase 1 -2.30175
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -2.29767
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.29764
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.2975
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -2.29296
GAPVD1 GTPase activating protein and VPS9 domains 1 -2.29175
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.28984
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.28948
EIF3D eukaryotic translation initiation factor 3, subunit D -2.28885
LRPPRC leucine-rich pentatricopeptide repeat containing -2.28859
EIF4B eukaryotic translation initiation factor 4B -2.28453
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -2.28192
CLCC1 chloride channel CLIC-like 1 -2.2796
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.2697
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -2.2681
GSTM5 glutathione S-transferase mu 5 -2.26642
ENOPH1 enolase-phosphatase 1 -2.26559
DNM1 dynamin 1 -2.26509
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.26461
SENP6 SUMO1/sentrin specific peptidase 6 -2.26453
LMNB1 lamin B1 -2.26445
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.26438
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.26116
MGA MGA, MAX dimerization protein -2.25793
CDKN3 cyclin-dependent kinase inhibitor 3 -2.25331
DCAF6 DDB1 and CUL4 associated factor 6 -2.2532
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.25154
NBAS neuroblastoma amplified sequence -2.24388
AVL9 AVL9 homolog (S. cerevisiase) -2.24166
LYPLA1 lysophospholipase I -2.2412
IL16 interleukin 16 -2.23789
CEP83 centrosomal protein 83kDa -2.23645
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.22505
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.22443
SAE1 SUMO1 activating enzyme subunit 1 -2.22397
SETD3 SET domain containing 3 -2.22208
KYAT1 kynurenine aminotransferase 1 -2.21996
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -2.21857
YARS1 tyrosyl-tRNA synthetase 1 -2.21595
SPATS2 spermatogenesis associated, serine-rich 2 -2.21211
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -2.21059
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.20715
MAN2A1 mannosidase, alpha, class 2A, member 1 -2.20517
ACOX2 acyl-CoA oxidase 2, branched chain -2.20432
CCSER2 coiled-coil serine-rich protein 2 -2.20296
TMEM135 transmembrane protein 135 -2.20068
CCNG1 cyclin G1 -2.20055
MBNL1 muscleblind-like splicing regulator 1 -2.19988
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.19762
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.18644
SEC24B SEC24 family member B -2.18486
PPARG peroxisome proliferator-activated receptor gamma -2.18389
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -2.18294
SEPTIN9 septin 9 -2.17425
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.17419
APEH acylaminoacyl-peptide hydrolase -2.17358
GET1 guided entry of tail-anchored proteins factor 1 -2.1733
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.17201
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.17111
BARX2 BARX homeobox 2 -2.17094
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.1632
FPGS folylpolyglutamate synthase -2.16301
APOLD1 apolipoprotein L domain containing 1 -2.16254
AURKA aurora kinase A -2.15898
APOO apolipoprotein O -2.15794
XPO1 exportin 1 -2.15381
EVL Enah/Vasp-like -2.15326
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -2.15326
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -2.15044
VWA8 von Willebrand factor A domain containing 8 -2.14745
COPS5 COP9 signalosome subunit 5 -2.14341
TASOR transcription activation suppressor -2.14085
VDAC1 voltage-dependent anion channel 1 -2.13721
POT1 protection of telomeres 1 -2.13342
FOXO3 forkhead box O3 -2.13194
TRH thyrotropin-releasing hormone -2.13127
AVEN apoptosis, caspase activation inhibitor -2.13119
ARID4B AT rich interactive domain 4B (RBP1-like) -2.1292
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.12701
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.1264
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.12621
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.12296
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.11992
COASY CoA synthase -2.11976
CEP290 centrosomal protein 290kDa -2.11875
LOC124907782 dual specificity protein phosphatase 22 -2.11427
TOP2A topoisomerase (DNA) II alpha 170kDa -2.11178
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.1113
ANO10 anoctamin 10 -2.11113
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -2.10653
PPP1R12A protein phosphatase 1, regulatory subunit 12A -2.10637
AP2B1 adaptor-related protein complex 2, beta 1 subunit -2.10335
GDI2 GDP dissociation inhibitor 2 -2.10316
TCF12 transcription factor 12 -2.10251
DENND4C DENN/MADD domain containing 4C -2.10248
UGP2 UDP-glucose pyrophosphorylase 2 -2.10083
ANKRD17 ankyrin repeat domain 17 -2.09616
MSN moesin -2.09175
FER fer (fps/fes related) tyrosine kinase -2.09099
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -2.08665
FMNL3 formin-like 3 -2.08655
THYN1 thymocyte nuclear protein 1 -2.08133
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.07892
NUSAP1 nucleolar and spindle associated protein 1 -2.07854
CCDC91 coiled-coil domain containing 91 -2.07781
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.07338
PARP1 poly (ADP-ribose) polymerase 1 -2.0697
FOXF1 forkhead box F1 -2.06938
FBXL5 F-box and leucine-rich repeat protein 5 -2.06531
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -2.06194
GIN1 gypsy retrotransposon integrase 1 -2.06135
UCK2 uridine-cytidine kinase 2 -2.055
CHEK2 checkpoint kinase 2 -2.05333
MRTFB myocardin related transcription factor B -2.04782
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -2.04424
PFAS phosphoribosylformylglycinamidine synthase -2.04191
SRPK1 SRSF protein kinase 1 -2.0417
SEPTIN7 septin 7 -2.04108
PCDHB16 protocadherin beta 16 -2.0378
GYG1 glycogenin 1 -2.03757
SSBP2 single-stranded DNA binding protein 2 -2.03753
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.03699
TMEM243 transmembrane protein 243, mitochondrial -2.0348
TRIM44 tripartite motif containing 44 -2.03239
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -2.03119
TNIK TRAF2 and NCK interacting kinase -2.03063
SLC38A6 solute carrier family 38, member 6 -2.03059
HAUS4 HAUS augmin-like complex, subunit 4 -2.02856
BBX bobby sox homolog (Drosophila) -2.02767
CDK8 cyclin-dependent kinase 8 -2.02175
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.02117
WDR12 WD repeat domain 12 -2.01855
TAOK3 TAO kinase 3 -2.01615
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.00968
ASXL2 additional sex combs like transcriptional regulator 2 -2.00835
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.00797
DSE dermatan sulfate epimerase -2.0026
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.00209