| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | omeprazole 33.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
91 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:D02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNRIP1 | cannabinoid receptor interacting protein 1 | 5.0 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 4.9255 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.82325 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.89227 |
| CHEK1 | checkpoint kinase 1 | 3.68643 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.325 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.10182 |
| WIF1 | WNT inhibitory factor 1 | 3.06265 |
| CCNA1 | cyclin A1 | 2.99085 |
| VSNL1 | visinin-like 1 | 2.83888 |
| LRRC40 | leucine rich repeat containing 40 | 2.57875 |
| LINC02762 | long intergenic non-protein coding RNA 2762 | 2.55 |
| CCL23 | chemokine (C-C motif) ligand 23 | 2.45762 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 2.44594 |
| STMN2 | stathmin 2 | 2.44022 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 2.4347 |
| NSF | N-ethylmaleimide-sensitive factor | 2.4199 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.34795 |
| FXYD7 | FXYD domain containing ion transport regulator 7 | 2.3318 |
| SYN1 | synapsin I | 2.3296 |
| ADAM23 | ADAM metallopeptidase domain 23 | 2.2715 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.2571 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 2.22735 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 2.22115 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 2.14325 |
| TMEM14B | transmembrane protein 14B | 2.1403 |
| SV2B | synaptic vesicle glycoprotein 2B | 2.1292 |
| PEG3 | paternally expressed 3 | 2.1192 |
| CLEC4M | C-type lectin domain family 4, member M | 2.1154 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 2.10115 |
| WDR41 | WD repeat domain 41 | 2.09775 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2.0861 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | 2.08508 |
| FMNL3 | formin-like 3 | 2.08285 |
| RUNX3 | runt-related transcription factor 3 | 2.07873 |
| SUMO4 | small ubiquitin-like modifier 4 | 2.05555 |
| MPC2 | mitochondrial pyruvate carrier 2 | 2.04385 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.02885 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.01935 |
| EPS8L2 | EPS8-like 2 | 2.01855 |
| KRT19 | keratin 19, type I | 2.013 |
| SUOX | sulfite oxidase | 2.01135 |
| SNX7 | sorting nexin 7 | 2.00925 |
| C1QB | complement component 1, q subcomponent, B chain | 2.0092 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | 2.00515 |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H | 2.0039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -5.5536 |
| TRAPPC3 | trafficking protein particle complex 3 | -5.06055 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -4.7724 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.69455 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.47285 |
| RHOT2 | ras homolog family member T2 | -3.4943 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.93365 |
| NAA60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit | -2.90215 |
| TKT | transketolase | -2.8902 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -2.86905 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.8191 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.7242 |
| ANXA2 | annexin A2 | -2.63322 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -2.6312 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -2.61395 |
| MAP7D1 | MAP7 domain containing 1 | -2.54985 |
| LUC7L | LUC7-like (S. cerevisiae) | -2.54945 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.5319 |
| HMOX2 | heme oxygenase 2 | -2.4774 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -2.42405 |
| PGAP6 | post-GPI attachment to proteins 6 | -2.3538 |
| DEXI | Dexi homolog (mouse) | -2.3467 |
| CDK4 | cyclin-dependent kinase 4 | -2.3344 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.331 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -2.32975 |
| PLCG1 | phospholipase C, gamma 1 | -2.31327 |
| WDR6 | WD repeat domain 6 | -2.30845 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -2.2943 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -2.29355 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | -2.25905 |
| STX11 | syntaxin 11 | -2.25185 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -2.2329 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.23175 |
| UBN1 | ubinuclein 1 | -2.22375 |
| ZNF263 | zinc finger protein 263 | -2.1574 |
| CAPN15 | calpain 15 | -2.1536 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | -2.146 |
| CLASRP | CLK4-associating serine/arginine rich protein | -2.1272 |
| MYT1 | myelin transcription factor 1 | -2.1163 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.1118 |
| JADE1 | jade family PHD finger 1 | -2.0727 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | -2.05315 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q | -2.0514 |
| JPT2 | Jupiter microtubule associated homolog 2 | -2.04447 |
| AGO1 | argonaute RISC catalytic component 1 | -2.00405 |
